Results 11 to 20 of about 992 (149)
错配修复蛋白hMLH1在子宫内膜癌表达的临床意义 [PDF]
Zhongshan Daxue xuebao. Yixue kexue ban, 2005 【目的】 探讨错配修复蛋白hMLH1在子宫内膜癌(endometrial carcinoma，EC)的失表达情况及其临床意义。【方法】 用免疫组化S-P方法检测hMLH1蛋白在61例子宫内膜癌组织的失表达情况，并分析hMLH1蛋白失表达与子宫内膜癌临床病理的关系。【结果】 子宫内膜癌组织存在hMLH1蛋白失表达，其失表达率为29.5％。hMLH1失表达子宫内膜癌细胞分化较好(P=0.047)，临床预后较好(OR=5.458，P=0.025)，hMLH1失表达为子宫内膜癌独立预后因素(Cox多因素分析，P=
林美芳
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Zhongshan Daxue xuebao. Yixue kexue ban, 2019 目的】探讨异常子宫出血（AUB）的子宫内膜病理类型及其与患者的年龄、体质量指数、腰围、臀围和腰臀比等因素相关关系。【方法】收集2017年1月至6月在中山大学附属第三医院日间手术室因AUB进行诊断性刮宫或宫腔镜检查并子宫内膜活检的206名病人资料，包括年龄、身高、体质量、腰围、臀围、子宫内膜病理等，进行相关统计分析。【结果】①子宫内膜病理类型有增殖期或分泌期子宫内膜（NE），子宫内膜部分增殖、部分分泌改变（DPE），子宫内膜息肉（EP），子宫内膜增生改变和（或）增生过长（EHwithoutatypia ...
张宇, 成娟, 叶青剑, 李小毛
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Microsatellite Instability and Its Clinical Significance in Endometrial Carcinoma [PDF]
, 2022 BackgroundThe role of microsatellite instability in the progression of endometrial cancer, a common cancer in women, has obtained increasing attentions in recent years.
XIAO Jing, WU Ying
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Ultrasound in Obstetrics &Gynecology, Volume 60, Issue 5, Page 604-611, November 2022., 2022 ABSTRACT Objectives To evaluate and compare the diagnostic test accuracy (DTA) of three‐dimensional transvaginal ultrasound (3D‐TVS) and magnetic resonance imaging (MRI) for deep myometrial infiltration (DMI) and cervical invasion for preoperative staging and surgery planning in patients with endometrial cancer (EC).
G. Spagnol +9 more
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The latest progress and prospect of gynecological tumor treatment at 2023 ESMO [PDF]
, 2023 Many major research achievements have been made in the past year in the field of gynecologic oncology (cervical cancer, ovarian cancer and endometrial cancer), including surgical treatment, local advanced treatment mode and exploration of new treatments ...
XIA Lingfang, ZHU Jun, WU Xiaohua
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Chinese expert consensus on immunotherapy for gynecological malignant tumors (2023 edition) [PDF]
, 2023 Immunotherapy, as the fourth largest anti-tumor treatment method, has made breakthrough progress in the field of cancer treatment. Checkpoint inhibitors have been widely used in the treatment of various malignant tumors, and a lot of clinical evidence ...
Society of Onco-Endocrinology of Chinese Anti-Cancer Association
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Expert consensus on genetic counseling in gynecological oncology (2023 edition) [PDF]
, 2023 With the increasing applications of high-throughput genome sequencing technology, there is a growing recognition of the important roles of genetic factors in the occurrence and development of gynecological tumors.
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Mechanism of METTL14-mediated ERα m6A regulation of endometrial cancer metastasis [PDF]
, 2023 Background and purpose: Aberrant N6-methyladenosine (m6A) modification caused by dysregulation of methyltransferase-like factor 14 (METTL14) plays an important role in the progression of various cancers, and it is unclear whether it is involved in the ...
ZHAO Manying, WU Dongyue, DU Ruiting, YIN Lu, LUO Yulu
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Study on the Mediating Effect of Intimate Relationship between Dyadic Coping and Quality of Life in Gynecological Cancer Patients' Couples [PDF]
, 2022 BackgroundDyadic coping are associated with quality of life in gynecologic cancer patients, but the mechanism path of action is still unclear.ObjectiveTo explore the mechanism of intimate relationship between dyadic coping and quality of life in ...
YE Huihui, GE Lina, ZANG Shuang, HU Shuang
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The Inhibitory Effect of GSNO to Endometrial Cancer and Preliminary Study of the Mechanisms [PDF]
, 2017 目的：近年来子宫内膜癌发病率不断上升，严重影响女性健康，目前子宫内膜癌治疗手段仍以传统的手术治疗为主，辅以放疗、化疗、内分泌治疗等，毒副作用大，对患者的生活质量及恢复造成不良影响。分子靶向治疗药物具有特异性强，毒副作用小等优势，成为目前肿瘤治疗界的研究热点。S-亚硝基谷胱甘肽（GSNO）已被证实对多种恶性肿瘤有治疗作用。本课题拟通过体内外实验，探究GSNO对子宫内膜癌细胞生长的抑制作用，并对其可能的作用机制进行初步探讨，为子宫内膜癌的分子靶向治疗提供新的思路。 方法 ...
李清
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