Results 21 to 30 of about 1,996 (175)

宫腔镜检查在子宫内膜癌临床诊断中的应用价值

open access: greenZhongguo shiyan zhenduanxue, 2010
目的探讨宫腔镜诊断子宫内膜癌的临床价值。方法回顾性分析了65例子宫内膜癌患者的临床资料,以手术病理结果为金标准,将术前分段诊刮和宫腔镜检查结果分别与手术病理结果对照分析。结果(1)33例宫腔镜组患者诊断为子宫内膜癌30例,诊断符合率为90.9%;32例诊刮术组患者诊断为子宫内膜癌17例,诊断符合率为53.1%,两组比较有显著性差异 ...
尹德娥, 李玉
doaj   +1 more source

ER和PR在子宫内膜癌和宫颈癌中表达比较及意义

open access: greenZhongguo shiyan zhenduanxue, 2017
目的探讨雌激素受体(ER)、孕激素受体(PR)在子宫内膜癌和宫颈癌组织中的表达率比较及其临床意义。方法应用EnVision两步法免疫组化技术对59例子宫内膜癌和61例宫颈癌组织进行ER、PR检测,回顾分析临床及病理特征。结果子宫内膜癌中ER和PR在的阳性表达率和子宫颈癌的阳性表达率无显著差异,两者的阳性表达都和组织学分级密切相关,组织学分级越高,它的激素阳性表达率越低,有统计学意义(P0.05)。结论雌孕激素ER、PR水平的病理表达是可以作为判断子宫内膜癌和宫颈癌的指标 ...
杨旭红   +3 more
doaj   +1 more source

Versican、CTGF、TGFβ1在子宫内膜样腺癌及子宫内膜上皮内瘤变中的表达和意义

open access: greenZhongguo shiyan zhenduanxue, 2016
目的探讨多功能蛋白聚糖(Versican)、结缔组织生长因子(CTGF)、转化生长因子β1(TGFβ1)在子宫内膜样腺癌(EA)及子宫内膜上皮内瘤变(EIN)中的表达及三者相关性。方法采用免疫组织化学方法对76例EA和35例EIN中Versican、CTGF、TGFβ1的表达情况进行了分析,阐述其在EA及EIN中的表达特征及相互关系。结果在76例EA中Versican、CTGF、TGFβ1阳性表达率分别为75%,65.8%,69.7%,在35例EIN中阳性表达率分别为42.9%,37.1%,37.1 ...
汪锋   +6 more
doaj   +1 more source

DEPDC1B及CDK1在子宫内膜癌中的表达及临床意义

open access: greenZhongguo shiyan zhenduanxue
目的探讨DEP结构域蛋白1B(DEPDC1B)和周期蛋白依赖性激酶1(CDK1)在子宫内膜癌中的表达及临床意义。方法利用GEPIA2数据库分析DEPDC1B和CDK1在子宫内膜癌中的表达情况;收集哈尔滨医科大学附属第四医院于2022年6月至2024年9月收治的86例患者的临床资料及石蜡标本(包括正常子宫内膜20例、子宫内膜非典型增生20例及子宫内膜癌46例),采用免疫组织化学法检测DEPDC1B和CDK1在不同子宫内膜组织中的表达水平,分析两者在子宫内膜癌中表达的相关性及与临床病理特征的关系 ...
张迪, 张帅丰, 成荣杰
doaj   +1 more source

Microsatellite Instability and Its Clinical Significance in Endometrial Carcinoma [PDF]

open access: yes, 2022
BackgroundThe role of microsatellite instability in the progression of endometrial cancer, a common cancer in women, has obtained increasing attentions in recent years.
XIAO Jing, WU Ying
core   +1 more source

Three‐dimensional transvaginal ultrasound vs magnetic resonance imaging for preoperative staging of deep myometrial and cervical invasion in patients with endometrial cancer: systematic review and meta‐analysis

open access: yesUltrasound in Obstetrics &Gynecology, Volume 60, Issue 5, Page 604-611, November 2022., 2022
ABSTRACT Objectives To evaluate and compare the diagnostic test accuracy (DTA) of three‐dimensional transvaginal ultrasound (3D‐TVS) and magnetic resonance imaging (MRI) for deep myometrial infiltration (DMI) and cervical invasion for preoperative staging and surgery planning in patients with endometrial cancer (EC).
G. Spagnol   +9 more
wiley   +1 more source

Chinese expert consensus on immunotherapy for gynecological malignant tumors (2023 edition) [PDF]

open access: yes, 2023
Immunotherapy, as the fourth largest anti-tumor treatment method, has made breakthrough progress in the field of cancer treatment. Checkpoint inhibitors have been widely used in the treatment of various malignant tumors, and a lot of clinical evidence ...
Society of Onco-Endocrinology of Chinese Anti-Cancer Association
core   +1 more source

The latest progress and prospect of gynecological tumor treatment at 2023 ESMO [PDF]

open access: yes, 2023
Many major research achievements have been made in the past year in the field of gynecologic oncology (cervical cancer, ovarian cancer and endometrial cancer), including surgical treatment, local advanced treatment mode and exploration of new treatments ...
XIA Lingfang, ZHU Jun, WU Xiaohua
core   +1 more source

肿瘤相关糖类抗原Tn在子宫内膜癌中异常表达及其生物学意义

open access: greenZhongguo shiyan zhenduanxue
目的 探索肿瘤相关糖类抗原Tn在子宫内膜癌病人中的表达及其生物学意义。方法 首先采用免疫组化染色(IHC)技术检测人子宫内膜癌组织、子宫内膜非典型增生组织和正常子宫内膜组织的Tn抗原表达状况;然后采用CRISPR/Cas9技术特异性敲除人子宫内膜癌细胞(Ishikawa、HEC-1B)的Cosmc基因以诱导Tn抗原表达;应用流式细胞技术检测Tn抗原的表达,并采用Transwell实验检测Tn抗原异常表达对子宫内膜癌细胞迁移和侵袭能力的影响;最后采用western ...
茹晓莉, 曹广明, 刘崇东
doaj   +1 more source

Expert consensus on genetic counseling in gynecological oncology (2023 edition) [PDF]

open access: yes, 2023
With the increasing applications of high-throughput genome sequencing technology, there is a growing recognition of the important roles of genetic factors in the occurrence and development of gynecological tumors.

core   +1 more source

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