Results 21 to 30 of about 1,006 (120)

妊娠晚期血脂水平与不同类型子痫前期相关性分析

Zhongshan Daxue xuebao. Yixue kexue ban, 2016
摘 要: 【目的】 通过比较子痫前期不同发病类型患者妊娠晚期血脂指标的变化,探讨血脂代谢异常与不同发病类型子痫前期的发生发展的相关性? 【方法】 收集子痫前期患者198例:轻度子痫前期108例,晚发型重度子痫前期54例,早发型重度子痫前期36例?选择同期无妊娠并发症的健康孕妇200例为对照组?检测血清总胆固醇(TC)?甘油三脂( TG)?高密度脂蛋白( HDLC)?低密度脂蛋白( LDLC)?载脂蛋白 A( ApoA)?载脂蛋白 B( ApoB)?计算AI?LDLC/HDLC?ApoB/ApoA进行比较?
苏秀梅
doaj  

Effect of aspirin on maternal hemodynamics in Chinese women at high risk for preterm pre‐eclampsia: longitudinal study

Ultrasound in Obstetrics &Gynecology, Volume 66, Issue 5, Page 621-630, November 2025.
ABSTRACT Objectives To compare the maternal hemodynamics of Chinese women at low and at high risk for preterm pre‐eclampsia (PE) and assess the differences in hemodynamic parameters between high‐risk women with or without prophylactic aspirin. Methods This was a prospective longitudinal case–control study of 857 Chinese women with a singleton pregnancy
X. Wang, J. Lin, Y. Chen, I. S. Wong, J. Liu, F. Liu, S. L. Lau, Q. Zhang, X. Xu, D. S. Sahota, A. P. W. Lee, L. C. Poon   +11 more
wiley   +1 more source

Role of aspirin therapy in modulating uterine artery resistance and placental growth between first and second trimesters of pregnancy

Ultrasound in Obstetrics &Gynecology, Volume 66, Issue 5, Page 641-648, November 2025.
ABSTRACT Objective To evaluate the impact of low‐dose aspirin (LDA) on placental size and uterine artery pulsatility index (UtA‐PI) by analyzing longitudinal changes between the first and second trimesters in pregnancies at high risk for early‐onset pre‐eclampsia (PE).
C. Trilla, J. Platero, J. Mora, M. N. Nan, C. Medina, O. Alejos, J. Parra, E. Llurba   +7 more
wiley   +1 more source

Annexin5、ET-1、vWF在子痫前期患者胎盘中的表达

Zhongguo shiyan zhenduanxue, 2014
目的研究子痫前期患者胎盘中Annexin5、ET-1、vWF的表达水平,并探讨子痫前期发病机制。方法采用免疫组化方法检测子痫前期患者84例（轻度29例、早发重度型27例、晚发重度型28例）及对照组29例胎盘组织中Annexin5、ET-1、vWF的表达水平。结果①胎盘中Annexin 5在子痫前期各组表达强度明显低于对照组,差异均有统计学意义（P0.05）。②胎盘中ET-1在子痫前期各组表达强度明显高于对照组,差异有统计学意义（P晚发型>轻度子痫前期患者,差异仍有统计学意义 ...
任春丽, 唐兴国, 任磊
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Aspirin delays preterm birth in pregnancies at high risk for preterm pre‐eclampsia: evidence from randomized clinical trial in Asia

Ultrasound in Obstetrics &Gynecology, Volume 66, Issue 1, Page 24-32, July 2025.
ABSTRACT Objectives To investigate the impact of aspirin administration on the incidence of preterm birth, according to the type of delivery and gestational age at preterm birth, and to examine the hypothesis that aspirin delays preterm delivery. Methods This was a secondary analysis of a multicenter stepped‐wedge cluster randomized trial of a first ...
H. H. Y. Leung, I. Papastefanou, Y. Chen, L. Nguyen‐Hoang, D.‐A. Nguyen, L. T. Dinh, R. K. Pooh, A. Shiozaki, M. Zheng, Y. Hu, Y. Wu, A. Kusuma, P. Yapan, A. Gosavi, A. Sekizawa, S. Luewan, T.‐Y. Chang, N. Chaiyasit, T. Nanthakomon, H. Liu, S. W. Shaw, W. C. Leung, A. S. Mohamad, A. Aguilar, S. L. Lau, N. M. W. Lee, J. Lin, D. S. Sahota, M. K. C. Chong, L. C. Poon   +29 more
wiley   +1 more source

血浆sCD40L、sICAM-1及血管内皮损伤相关细胞与子痫前期严重程度的相关性分析

Zhongguo shiyan zhenduanxue, 2017
目的探讨血浆白细胞分化抗原可溶性CD40配体（sCD40L）、可溶性细胞间粘附因子-1（sICAM-1）及血管内皮损伤相关细胞与子痫前期严重程度的相关性。方法选择年龄、BMI、检测孕周等临床一般资料相匹配的重度子痫前期、轻度子痫前期患者以及健康孕妇（对照组）各45例作为研究对象,采用ELISA法检测血浆sCD40L、sICAM-1水平,采用流式细胞仪检测内皮祖细胞（EPC）、血管生成性T细胞（Tang）含量,比较并分析其相关性。结果子痫前期组的血浆sICAM-1、sCD40L水平均明显高于对照组 ...
薛峰, 颜源, 何攀
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血清TLR4及MFG-E8与子痫前期患者表达及发生早期肾损伤的关系

Zhongguo shiyan zhenduanxue, 2020
目的研究子痫前期患者外周血中TLR4和MFG-E8在子痫前期患者中的表达与诊断意义,并探讨其与子痫前期发生早期肾损伤的关系。方法用酶联免疫吸附法对妊娠期高血压患者30例,轻度子痫前期患者30例、重度子痫前期30例以及正常妊娠30例患者外周血中TLR4和MFG-E8表达水平。结果①外周血TLR4表达水平随病情加重呈逐渐升高趋势,sPE>mPE>GH>NP组;外周血MFG-E8表达水平随病情加重呈逐渐降低趋势 ...
任春丽, 唐兴国, 张玉芳, 袁晓明   +3 more
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Assessment of risk for pre‐eclampsia at mid‐gestation to define subsequent care

Ultrasound in Obstetrics &Gynecology, Volume 65, Issue 6, Page 694-702, June 2025.
ABSTRACT Objective To stratify pregnancy care based on the estimated risk of pre‐eclampsia (PE) from screening at 19–24 weeks' gestation by combinations of maternal risk factors, estimated fetal weight (EFW), mean arterial pressure (MAP) and uterine artery pulsatility index (UtA‐PI).
S. Adjahou, V. Logdanidis, A. Wright, A. Syngelaki, R. Akolekar, K. H. Nicolaides   +5 more
wiley   +1 more source

syncytin在妊娠期高血压疾病胎盘滋养细胞中的表达研究

Zhongguo shiyan zhenduanxue, 2011
目的检测胎盘滋养细胞中syncytin的表达,探讨其在妊娠期高血压疾病发病中的意义。方法采用West-ern blot法测定syncytin蛋白表达强度,其中妊娠期高血压10例,重度子痫前期15例,轻度子痫前期15例,子痫组5例;正常晚期妊娠20例。结果五组均检测到syncytin蛋白的表达;子痫组syncytin蛋白表达强度最低（8.58±0.81）,重度子痫前期组（9.11±0.43）,轻度子痫前期组（10.64±0.36）,妊娠期高血压组为（11.30±2.23）,均明显低于正常晚期妊娠组（20 ...
邬俏璇, 罗炳德, 王晨虹, 周璐
doaj  

Placental biomarker and fetoplacental Doppler abnormalities are strongly associated with placental pathology in pregnancies with small‐for‐gestational‐age fetus: prospective study

Ultrasound in Obstetrics &Gynecology, Volume 65, Issue 6, Page 749-760, June 2025.
ABSTRACT Objective Placental dysfunction can result in small‐for‐gestational age (SGA) or fetal growth restriction (FGR). The aim of this prospective cohort study was to assess the association of the cerebroplacental ratio (CPR) and other more conventional fetoplacental Doppler indices, circulating placental growth factor (PlGF) levels and soluble fms ...
J. Hong, K. Crawford, E. Cavanagh, V. Clifton, F. da Silva Costa, A. V. Perkins, S. Kumar   +6 more
wiley   +1 more source