Results 31 to 40 of about 1,006 (120)

CRMP-1在早发型先兆子痫妇女胎盘中的表达水平及临床意义

Zhongguo shiyan zhenduanxue, 2018
目的检测早发型先兆子痫妇女胎盘中坍塌反应调节蛋白-1(CRMP-1)的表达,分析其与先兆子痫临床特点的关系。方法收集30例早发型先兆子痫、30例迟发型先兆子痫孕妇作为研究对象,另选取同时期因各种原因终止妊娠的健康孕妇60例,将其按照孕周进行匹配分别作为早发型先兆子痫的对照组A、迟发型先兆子痫的对照组B。采用免疫组化法检测各组孕妇胎盘组织中CRMP-1的表达情况,并进行各分组间的分析。结果健康孕妇胎盘组织中CRMP-1的表达量随孕周呈下降趋势,妊娠早期CRMP-1的强阳性表达量明显高于妊娠晚期 ...
袁银花, 冯双苗, 张化莲
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Screening for pre‐eclampsia using pregnancy‐associated plasma protein‐A or placental growth factor measurements in blood samples collected at 8–14 weeks' gestation

Ultrasound in Obstetrics &Gynecology, Volume 65, Issue 5, Page 567-574, May 2025.
ABSTRACT Objectives To assess the value of pregnancy‐associated plasma protein‐A (PAPP‐A) in screening for preterm pre‐eclampsia (PE) (delivery < 37 weeks' gestation) measured in maternal blood samples collected before 11 weeks, and to compare the screening performance of PAPP‐A with that of placental growth factor (PlGF) from blood samples collected ...
L. Rode, A. Wright, D. Wright, M. Overgaard, L. Sperling, P. Sandager, P. Nørgaard, F. S. Jørgensen, H. Zingenberg, I. Riishede, A. Tabor, C. K. Ekelund, the PRESIDE Study Group, M. R. Andersen, L. Bathum, C. A. Juel Jensen, C. S. Knudsen, N. G. Pedersen, K. Pihl, C. Vedel, H. Skov, S. R. Wagner   +21 more
wiley   +1 more source

N‐terminal pro B‐type natriuretic peptide as biomarker to predict pre‐eclampsia and maternal–fetal complications

Ultrasound in Obstetrics &Gynecology, Volume 65, Issue 4, Page 447-455, April 2025.
ABSTRACT Objective A soluble fms‐like tyrosine kinase‐1 (sFlt‐1)‐to‐placental growth factor (PlGF) ratio cut‐off of 38 is currently considered optimal for ruling out pre‐eclampsia (PE); however, implementation of this ratio in clinical practice is limited.
M. N. Nan, C. Garrido‐Giménez, Á. Garcia‐Osuna, P. Garcia Manau, J. Ullmo, J. Mora, O. Sanchez‐Garcia, J. Platero, M. Cruz‐Lemini, E. Llurba, on behalf of the EuroPE working group, M. Vila‐Cortés, M. J. Pelegay, M. Ricart, B. Muñoz‐Abellana, X. Gabaldó Barrios   +15 more
wiley   +1 more source

Association of maternal body mass index with hemodynamic and vascular alterations at 35–37 weeks' gestation

Ultrasound in Obstetrics &Gynecology, Volume 65, Issue 3, Page 303-310, March 2025.
ABSTRACT Objective Globally, one in four pregnant women is classified as overweight or obese, based on their prepregnancy body mass index (BMI). Obese pregnant women are at increased risk of adverse pregnancy outcomes and long‐term cardiovascular disease that occurs earlier in life.
M. Charakida, C. Chatzakis, L. A. Magee, A. Syngelaki, T. Mansukhani, P. von Dadelszen, K. H. Nicolaides   +6 more
wiley   +1 more source

Prediction of pre‐eclampsia using maternal hemodynamic parameters at 12 + 0 to 15 + 6 weeks

Ultrasound in Obstetrics &Gynecology, Volume 65, Issue 2, Page 173-182, February 2025.
ABSTRACT Objectives To compare the maternal hemodynamic profile at 12 + 0 to 15 + 6 weeks' gestation in women who subsequently developed pre‐eclampsia (PE) and those who did not, and to assess the screening performance of maternal hemodynamic parameters for PE in combination with the Fetal Medicine Foundation (FMF) triple test, including maternal ...
X. Wang, D. S. Sahota, L. Wong, L. Nguyen‐Hoang, Y. Chen, A. S. T. Tai, F. Liu, S. Ling Lau, A. P. W. Lee, L. C. Poon   +9 more
wiley   +1 more source

Intermanufacturer assessment of diagnostic performance of angiogenic ratio vs glycosylated fibronectin in women with suspected pre‐eclampsia

Ultrasound in Obstetrics &Gynecology, Volume 64, Issue 5, Page 620-625, November 2024.
ABSTRACT Objective To compare the diagnostic performance of different manufacturers' immunoassays for the soluble fms‐like tyrosine kinase‐1 (sFlt‐1)‐to‐placental growth factor (PlGF) ratio with that of a point‐of‐care (PoC) test for glycosylated fibronectin (GlyFn) in women with suspected pre‐eclampsia (PE).
I. Y. M. Wah, D. S. Sahota, N. K. L. Wong, N. M. W. Lee, C. J. Liu, C. S. L. Lau, H. H. Y. Leung, L. C. Poon   +7 more
wiley   +1 more source

Maternal ethnicity and socioeconomic deprivation: influence on adverse pregnancy outcomes

Ultrasound in Obstetrics &Gynecology, Volume 64, Issue 2, Page 187-192, August 2024.
ABSTRACT Objective To evaluate the relative importance of ethnicity and socioeconomic deprivation in determining the likelihood and prevalence of placentally derived composite of adverse pregnancy outcomes (CAPO) and composite of severe adverse pregnancy outcomes (CAPO‐S).
M. Minopoli, L. Noël, A. Dagge, G. Blayney, A. Bhide, B. Thilaganathan   +5 more
wiley   +1 more source

Performance of machine‐learning approach for prediction of pre‐eclampsia in a middle‐income country

Ultrasound in Obstetrics &Gynecology, Volume 63, Issue 3, Page 350-357, March 2024.
ABSTRACT Objective Pre‐eclampsia (PE) is a serious complication of pregnancy associated with maternal and fetal morbidity and mortality. As current prediction models have limitations and may not be applicable in resource‐limited settings, we aimed to develop a machine‐learning (ML) algorithm that offers a potential solution for developing accurate and ...
J. Torres‐Torres, J. R. Villafan‐Bernal, R. J. Martinez‐Portilla, J. A. Hidalgo‐Carrera, G. Estrada‐Gutierrez, R. Adalid‐Martinez‐Cisneros, L. Rojas‐Zepeda, S. Acevedo‐Gallegos, D. M. Camarena‐Cabrera, M. Y. Cruz‐Martínez, S. Espino‐y‐Sosa   +10 more
wiley   +1 more source

Selective fetal growth restriction in dichorionic diamniotic twin pregnancy: systematic review and meta‐analysis of pregnancy and perinatal outcomes

Ultrasound in Obstetrics &Gynecology, Volume 63, Issue 2, Page 164-172, February 2024.
ABSTRACT Objective Most of the published literature on selective fetal growth restriction (sFGR) has focused on monochorionic twin pregnancies. The aim of this systematic review was to report on the outcome of dichorionic diamniotic (DCDA) twin pregnancies complicated by sFGR.
F. D'Antonio, S. Prasad, L. Masciullo, N. Eltaweel, A. Khalil   +4 more
wiley   +1 more source

miRNA在重度子痫前期与正常妊娠胎盘组织中差异表达的研究

Zhongguo shiyan zhenduanxue, 2015
目的分别检测重度子痫前期和正常妊娠妇女胎盘组织中微小RNA(miRNA)的表达情况,并初步探讨miRNA的差异表达在重度子痫前期发生发展过程中的意义。方法在我院住院剖宫产分娩的产妇中,选取5例重度子痫前期患者(实验组),5例正常妊娠孕妇(对照组),通过miRNA芯片技术检测实验组与对照组胎盘组织中miRNA的表达情况。结果本实验共检测了391个miRNA的表达谱,实验组与对照组组间比较,差异表达的miRNA共有81个,其中表达上调的有80个,表达下调的有1个,主要涉及细胞分化、血管重塑 ...
蒋涛涛, 孙波, 沈梅, 董洁, 骆琦   +4 more
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