Results 41 to 50 of about 1,890 (194)
Annexin5、ET-1、vWF在子痫前期患者胎盘中的表达
Zhongguo shiyan zhenduanxue, 2014 目的研究子痫前期患者胎盘中Annexin5、ET-1、vWF的表达水平,并探讨子痫前期发病机制。方法采用免疫组化方法检测子痫前期患者84例（轻度29例、早发重度型27例、晚发重度型28例）及对照组29例胎盘组织中Annexin5、ET-1、vWF的表达水平。结果①胎盘中Annexin 5在子痫前期各组表达强度明显低于对照组,差异均有统计学意义（P0.05）。②胎盘中ET-1在子痫前期各组表达强度明显高于对照组,差异有统计学意义（P晚发型>轻度子痫前期患者,差异仍有统计学意义 ...
任春丽, 唐兴国, 任磊
doaj
血清TLR4及MFG-E8与子痫前期患者表达及发生早期肾损伤的关系
Zhongguo shiyan zhenduanxue, 2020 目的研究子痫前期患者外周血中TLR4和MFG-E8在子痫前期患者中的表达与诊断意义,并探讨其与子痫前期发生早期肾损伤的关系。方法用酶联免疫吸附法对妊娠期高血压患者30例,轻度子痫前期患者30例、重度子痫前期30例以及正常妊娠30例患者外周血中TLR4和MFG-E8表达水平。结果①外周血TLR4表达水平随病情加重呈逐渐升高趋势,sPE>mPE>GH>NP组;外周血MFG-E8表达水平随病情加重呈逐渐降低趋势 ...
任春丽 +3 more
doaj
Maternal ethnicity and socioeconomic deprivation: influence on adverse pregnancy outcomes
Ultrasound in Obstetrics &Gynecology, Volume 64, Issue 2, Page 187-192, August 2024.ABSTRACT Objective To evaluate the relative importance of ethnicity and socioeconomic deprivation in determining the likelihood and prevalence of placentally derived composite of adverse pregnancy outcomes (CAPO) and composite of severe adverse pregnancy outcomes (CAPO‐S).
M. Minopoli +5 more
wiley +1 more source
血浆sCD40L、sICAM-1及血管内皮损伤相关细胞与子痫前期严重程度的相关性分析
Zhongguo shiyan zhenduanxue, 2017 目的探讨血浆白细胞分化抗原可溶性CD40配体（sCD40L）、可溶性细胞间粘附因子-1（sICAM-1）及血管内皮损伤相关细胞与子痫前期严重程度的相关性。方法选择年龄、BMI、检测孕周等临床一般资料相匹配的重度子痫前期、轻度子痫前期患者以及健康孕妇（对照组）各45例作为研究对象,采用ELISA法检测血浆sCD40L、sICAM-1水平,采用流式细胞仪检测内皮祖细胞（EPC）、血管生成性T细胞（Tang）含量,比较并分析其相关性。结果子痫前期组的血浆sICAM-1、sCD40L水平均明显高于对照组 ...
薛峰, 颜源, 何攀
doaj
Analysis of risk factors of adverse pregnancy outcomes in patients with chronic kidney disease [PDF]
Objective·To find out the risk factors leading to adverse pregnancy outcome by analyzing the correlation of clinical data and adverse pregnancy outcomes in patients with pregnancy complicated with chronic kidney disease.Methods·The clinical data before ...
LI Yu, ZHANG Yu
core +1 more source
Performance of machine‐learning approach for prediction of pre‐eclampsia in a middle‐income country
Ultrasound in Obstetrics &Gynecology, Volume 63, Issue 3, Page 350-357, March 2024.ABSTRACT Objective Pre‐eclampsia (PE) is a serious complication of pregnancy associated with maternal and fetal morbidity and mortality. As current prediction models have limitations and may not be applicable in resource‐limited settings, we aimed to develop a machine‐learning (ML) algorithm that offers a potential solution for developing accurate and ...
J. Torres‐Torres +10 more
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2018 目的检测早发型先兆子痫妇女胎盘中坍塌反应调节蛋白-1(CRMP-1)的表达,分析其与先兆子痫临床特点的关系。方法收集30例早发型先兆子痫、30例迟发型先兆子痫孕妇作为研究对象,另选取同时期因各种原因终止妊娠的健康孕妇60例,将其按照孕周进行匹配分别作为早发型先兆子痫的对照组A、迟发型先兆子痫的对照组B。采用免疫组化法检测各组孕妇胎盘组织中CRMP-1的表达情况,并进行各分组间的分析。结果健康孕妇胎盘组织中CRMP-1的表达量随孕周呈下降趋势,妊娠早期CRMP-1的强阳性表达量明显高于妊娠晚期 ...
袁银花, 冯双苗, 张化莲
doaj
Characteristics of imprinted differentially methylated regions in preeclampsia placenta [PDF]
ObjectiveTo investigate the characteristics of imprinted differentially methylated regions (iDMRs) in placentas and their correlation with preeclampsia (PE).
Huijun TANG +3 more
core +1 more source
孕妇外周血中游离胎儿DNA 浓度与不良妊娠结局的关系 [PDF]
, 2020 【目的】探讨游离胎儿DNA 浓度（FF）与不良妊娠结局的关系。【方法】对2017 年1 月至2018 年10 月在中山大学附属第三医院产科行无创产前检测并住院分娩的中国籍产妇 1 231 例进行回顾性分析，其中妊娠期高血压病（HDP）组、胎儿生长受限（FGR）组及早产组分别为 84、57 和 59 例作为病例组；将无妊娠并发症的孕妇1 031 例作为对照组。分析FF 与年龄、采血孕周、体质量指数（BMI）的相关性，比较病例组与对照组FF 的差异。【结果】行 NIPT 的 1031 例正常孕妇中 ...
侯红瑛 +3 more
core
Ultrasound in Obstetrics &Gynecology, Volume 63, Issue 2, Page 164-172, February 2024.ABSTRACT Objective Most of the published literature on selective fetal growth restriction (sFGR) has focused on monochorionic twin pregnancies. The aim of this systematic review was to report on the outcome of dichorionic diamniotic (DCDA) twin pregnancies complicated by sFGR.
F. D'Antonio +4 more
wiley +1 more source