Results 11 to 20 of about 7,139 (162)

Plasma mitochondrial DNA is elevated in maternal serum at first trimester and may serve as a biomarker for prediction of gestational diabetes mellitus 血浆线粒体DNA在妊娠早期孕妇血清中升高,可能成为预测妊娠期糖尿病的生物标志物

open access: yesJournal of Diabetes, Volume 15, Issue 12, Page 1095-1102, December 2023., 2023
Highlights In the first trimester, the plasma mitochondrial DNA (mtDNA) was higher in women who developed gestational diabetes mellitus (GDM) than in women who did not develop GDM during their pregnancy. The increased levels of plasma mtDNA were independent of age and fasting plasma glucose levels in the first trimester.
Dushyant Kumar Sahu, Jessy Abraham
wiley   +1 more source

Associations of blood biomarkers with arterial stiffness in patients with diabetes mellitus: A population‐based study 糖尿病患者血液生物标志物与动脉硬化的关系: 一项基于人群的研究

open access: yesJournal of Diabetes, Volume 15, Issue 10, Page 853-865, October 2023., 2023
Highlights Few studies have investigated the association of large‐scale biomarkers and pulse wave velocity (PWV) among diabetic patients. This study investigates the relationships of serum laboratory tests with PWV and explored the associations between PWV and all‐cause mortality among diabetic patients.
Yong‐Qi Liang   +9 more
wiley   +1 more source

Protective effects of nattokinase against microvasculopathy and neuroinflammation in diabetic retinopathy 纳豆激酶对糖尿病视网膜病变微血管病变和神经炎症的保护作用

open access: yesJournal of Diabetes, Volume 15, Issue 10, Page 866-880, October 2023., 2023
Highlights Nattokinase rescued endothelial dysfunction and pericyte loss in the diabetic retina. Nattokinase attenuated diabetes‐induced retinal inflammation and neurodegeneration. High mobility group box 1 signaling was involved in nattokinase‐mediated retinal protection.
Zijing Huang   +11 more
wiley   +1 more source

Ceramide changes in abdominal subcutaneous and visceral adipose tissue among diabetic and nondiabetic patients 糖尿病和非糖尿病患者腹部皮下和内脏脂肪组织神经酰胺的变化

open access: yesJournal of Diabetes, Volume 14, Issue 4, Page 271-281, April 2022., 2022
Highlights The gender‐specific role of sphingolipids in obesity‐related metabolic dysfunctions is unclear. The aim of this study is to identify ceramide species by liquid chromatography‐mass spectrometry that accumulate in central fat in relation to status of diabetes and gender for subjects with a body mass index ≥40 kg/m2 or > 35 kg/m2 with ...
Michelle Brusatori   +7 more
wiley   +1 more source

Percutaneous fetoscopic spina bifida repair: effect on ambulation and need for postnatal cerebrospinal fluid diversion and bladder catheterization

open access: yesUltrasound in Obstetrics &Gynecology, Volume 58, Issue 4, Page 582-589, October 2021., 2021
Abstract Objective A trial comparing prenatal with postnatal open spina bifida (OSB) repair established that prenatal surgery was associated with better postnatal outcome. However, in the trial, fetal surgery was carried out through hysterotomy. Minimally invasive approaches are being developed to mitigate the risks of open maternal–fetal surgery.
D. A. Lapa   +9 more
wiley   +1 more source

全基因體定序對兒童神經疾病的診斷率和治療影響

open access: yesDevelopmental Medicine &Child Neurology, Volume 63, Issue 8, Page e1-e4, August 2021., 2021
目的 探討全基因體定序 (WGS) 對兒童神經疾病的診斷率及治療影響。 方法 從 2016 年 1 月至 2019 年 12 月, 使用全基因體定序對疑似患有遺傳性神經疾病的兒科病人進行評估。符合條件的病人依其臨床表現型分為四組: 神經發展障礙病人、癲癇病人、神經肌肉疾病病人及運動障礙病人。我們描述全基因體定序的診斷率及經全基因體定序確診後對病人治療的影響。 結果 共有 214 例病人 (男性 128 例, 女性 86 例) 接受了全基因體定序檢測, 病人平均 (SD) 發病年齡為 13.8 (27.6) 個月, 範圍為 1 天至 15 年 5 個月, 接受全基因體定序檢測的平均 (SD) 年齡為 71.7 (58.9) 個月, 範圍從 8 天到 18 歲。 43.9 ...
李 秀芬, 遲景 上, 蔡 啟仁
wiley   +1 more source

Efficacy and safety of 0.0584% hydrocortisone aceponate topical spray and systemic oclacitinib combination therapy in dogs with atopic dermatitis: a randomized, double‐blinded, placebo‐controlled trial

open access: yesVeterinary Dermatology, Volume 32, Issue 2, Page 119-e25, April 2021., 2021
Background – Oclacitinib is an effective systemic therapy for dogs with atopic dermatitis (AD). Few studies have evaluated concurrent topical treatment with oclacitinib in dogs. Objectives – To evaluate the efficacy and safety of combination therapy of oclacitinib and 0.0584% hydrocortisone aceponate (HCA) spray in dogs with AD.
Junko Takahashi   +9 more
wiley   +1 more source

In vitro killing of canine strains of Staphylococcus pseudintermedius and Escherichia coli by cefazolin, cefovecin, doxycycline and pradofloxacin over a range of bacterial densities

open access: yesVeterinary Dermatology, Volume 31, Issue 3, Page 187-e39, June 2020., 2020
Background Bacterial densities likely fluctuate during infection and may exceed the bacterial density used in susceptibility testing. As such, investigation of bacterial killing by antibiotics over a range of varying bacterial densities may provide important differences between compounds and could impact drug selection for therapy.
Joseph M. Blondeau, Shantelle D. Fitch
wiley   +1 more source

CD40 is Positively Correlated with the Expression of Nucleophosmin in Cisplatin‐Resistant Bladder Cancer

open access: yesJournal of Oncology, Volume 2020, Issue 1, 2020., 2020
Objective. To verify and evaluate the value of CD40 as a noninvasive biomarker of cisplatin‐resistant bladder cancer, we studied the expression of CD40 and the correlation between nucleophosmin (NPM1) and CD40 in cisplatin‐resistant bladder cancer. Methods.
Chenshuo Luo   +5 more
wiley   +1 more source

Abstracts

open access: yes, 2022
Cancer Science, Volume 113, Issue S1, Page 1-1874, February 2022.
wiley   +1 more source

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