Results 21 to 30 of about 150,074 (154)
Developmental Medicine &Child Neurology, Volume 63, Issue 8, Page e1-e4, August 2021., 2021 目的 探討全基因體定序 (WGS) 對兒童神經疾病的診斷率及治療影響。 方法 從 2016 年 1 月至 2019 年 12 月, 使用全基因體定序對疑似患有遺傳性神經疾病的兒科病人進行評估。符合條件的病人依其臨床表現型分為四組: 神經發展障礙病人、癲癇病人、神經肌肉疾病病人及運動障礙病人。我們描述全基因體定序的診斷率及經全基因體定序確診後對病人治療的影響。 結果 共有 214 例病人 (男性 128 例, 女性 86 例) 接受了全基因體定序檢測, 病人平均 (SD) 發病年齡為 13.8 (27.6) 個月, 範圍為 1 天至 15 年 5 個月, 接受全基因體定序檢測的平均 (SD) 年齡為 71.7 (58.9) 個月, 範圍從 8 天到 18 歲。 43.9 ...
李 秀芬, 遲景 上, 蔡 啟仁
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Veterinary Dermatology, Volume 32, Issue 2, Page 119-e25, April 2021., 2021 Background – Oclacitinib is an effective systemic therapy for dogs with atopic dermatitis (AD). Few studies have evaluated concurrent topical treatment with oclacitinib in dogs. Objectives – To evaluate the efficacy and safety of combination therapy of oclacitinib and 0.0584% hydrocortisone aceponate (HCA) spray in dogs with AD.
Junko Takahashi +9 more
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Gongye shui chuli, 2022 针对源分离尿液富含氮、磷等多种营养元素，且具有较高资源回收潜力的特点，首先概述了源分离尿液的特征，重点总结了源分离尿液的氮、磷回收技术（浓缩脱水技术、吸附技术、化学沉淀技术、生物处理技术、电化学技术），并对各项技术的研究进展进行了阐述；然后分析了源分离尿液在农业生产和同步产电领域的应用价值；最后通过展望源分离尿液的发展趋势，指出未来应进一步提高源分离尿液处理过程中氮、磷资源的回收率并将其应用于实际污水处理，以期为真正实现源分离尿液的资源化、无害化和规模化提供参考。
王舒, 李楠
doaj +2 more sources
, 2023 圈养动物尿液中含有丰富的代谢产物，是代谢组学分析中用以判定动物发情、妊娠、健康状态、应激水平及动物福利的重要生物检材。因采样困难及安全考虑，目前多选择动物离开或转移后采集遗留在圈舍地面的尿液样本，这种样本容易被污染而影响检测结果，因此探索一种低污染、方便且快捷的尿液采集和预处理方法非常必要。针对8只（3♀，5）圈养大熊猫（Ailuropoda melanoleuca）的27份尿液样品，分别采用不做处理（对照组）、0.22 μm滤膜过滤和添加叠氮钠3种预处理方法，然后通过微生物培养 ...
耿珠峰 +12 more
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NMR联用HILIC-UPLC-MS/MS测定TNBS诱导的结肠炎大鼠尿液和血浆代谢物变化 [PDF]
, 2021 目的基于非靶标和靶标代谢组学技术，探讨三硝基苯磺酸（TNBS）诱导的结肠炎模型大鼠尿液以及血浆中内源性代谢物的变化。方法16只雄性SD大鼠随机分成对照组和模型组，每组8只，对模型组大鼠给予TNBS灌肠以建立实验性大鼠结肠炎模型。利用核磁共振氢谱（1H NMR）检测两组大鼠尿液代谢物，同时联用HILIC模式超高效液相色谱串联三重四级杆质谱（HILIC-UPLC-MS/MS）测定以上大鼠尿液以及血浆中氨基酸水平，并通过多元变量统计方法对代谢组学数据进行分析。结果同对照组相比，1H ...
邹宝荣 +7 more
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Veterinary Dermatology, Volume 31, Issue 3, Page 187-e39, June 2020., 2020 Background Bacterial densities likely fluctuate during infection and may exceed the bacterial density used in susceptibility testing. As such, investigation of bacterial killing by antibiotics over a range of varying bacterial densities may provide important differences between compounds and could impact drug selection for therapy.
Joseph M. Blondeau, Shantelle D. Fitch
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Journal of Oncology, Volume 2020, Issue 1, 2020., 2020 Objective. To verify and evaluate the value of CD40 as a noninvasive biomarker of cisplatin‐resistant bladder cancer, we studied the expression of CD40 and the correlation between nucleophosmin (NPM1) and CD40 in cisplatin‐resistant bladder cancer. Methods.
Chenshuo Luo +5 more
wiley +1 more source
A Green Anodic Electrolysis Strategy for Recovering Copper and Selenium From Cuprous Selenide
Rare Metals, Volume 45, Issue 3, March 2026.ABSTRACT Selenium, a rare strategic metal, is essential for advanced technologies and biological systems. Cuprous selenide (Cu2Se), a selenium‐rich compound found in copper anode slime and a promising thermoelectric material, holds great potential for recovery.
Jihua Li +7 more
wiley +1 more source
Salivary gland hypofunction in KK‐Ay type 2 diabetic mice
Journal of Diabetes, Volume 10, Issue 1, Page 18-27, January 2018., 2018 Abstract Background Hypofunction of different organs in the body is associated with diabetes, including in the oral cavity. Diabetes is often associated with xerostomia, but the underlying mechanism is not well characterized. Thus, the mechanisms underlying diabetes‐induced xerostomia were investigated in this study in KK‐A y mice as an experimental ...
Takashi Munemasa +8 more
wiley +1 more source