Results 1 to 10 of about 6,137 (162)
目的: 有报道糖皮质激素( GCs)亦可加重肾脏病蛋白尿。本课题旨在探讨 GCs 是否加重激素不敏感肾病综合征 ( NS)蛋白尿及其机制, 以指导临床合理使用 GCs。方法: 19 例对激素不敏感的 NS 患儿予泼尼松每日 1. 5~ 2 mg/kg 隔日早上 08∶ 00顿服。同时检测激素日和无激素日的尿蛋白及其成分、白蛋白和免疫球蛋白 G 及肌酐的清除率、肾有效血浆流量 ( ERPF)、尿前列腺素等并进行比较。结果: 与无激素日比较, 激素日尿蛋白明显增加( 2. 4 g±0. 5 g vs 1.
莫 樱 陈述枚
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Multiplemyeloma onset with kidney failure:one case report
病例资料王某,男,56岁,因"多饮、多尿2个月,水肿、发现肾功能异常10d"入我院,既往健康。入院检查,血压:120/75mmHg(1mmHg=0.133kPa),贫血貌,双下肢略水肿,心肺及腹部无明显阳性体征。化验血肌酐(Scr)401μmol/L;血尿酸472μmol/L;尿常规:尿蛋白+++,隐血+++;24h尿总蛋白1 620mg/d,24h尿白蛋白265mg/d;血红蛋白:81g/L;血白蛋白39.4g/L,球蛋白:21.2g/L;IgA:0.45g/L,IgM:0.37g/L,IgG:8 ...
YANG Shu-miao +2 more
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目的观察低血糖生成指数(low glycemic index,LGI)饮食联合丹参川芎嗪注射液对糖尿病肾病血糖、血脂、蛋白尿及肾功能的影响。方法将50例合并糖尿病肾病的2型糖尿病患者采用随机数字法随机分为治疗组(n=25)和对照组(n=25)。两组患者均采用正规胰岛素治疗,在严格执行LGI饮食、低盐低脂优质低蛋白饮食基础上,治疗组给予丹参川芎嗪注射液静滴;对照组不使用丹参川芎嗪注射液,连续4周。比较两组患者治疗前后空腹血糖、餐后2 h血糖、三酰甘油、胆固醇、24 h尿蛋白定量、尿白蛋白排泄率 ...
WANG Wen-jin +2 more
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EZSCAN风险评分在肾功能轻度损伤人群中的筛查价值 [PDF]
目的自主神经功能障碍是慢性肾脏病(CKD)患者常见严重的并发症,且在CKD早期就会发生。汗腺功能障碍已被视为自主神经功能紊乱的初始组成部分。通过反向离子电渗疗法和计时电流法测量电化学皮肤电导(ESC)来评估汗腺功能,可能会检测出健康体检人群中轻度肾功能不全的患者,以便给予早期干预与治疗,延缓肾功能进一步恶化。方法EZSCAN分数 (0~100) 是基于计时电流分析的专有算法计算得出的。本研究入组了2020年1月至10月浙江大学医学院附属第二医院体检中心健康体检的6 661名受试者,包括肾功能下降 ...
孙婷, 沈国丽, 蔡如意, 邵敏
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Relationships of Skin AGEs and Serum CN-1 with Microvascular Complications in Type 2 Diabetes Mellitus [PDF]
BackgroundHyperglycemia plays a significant role in the development and progression of diabetic complications. While carnosine is a putative scavenger of advanced glycation end products (AGEs) , its availability in tissue is limited by the activity of ...
YANG Guang, XU Xin, ZHANG Yu, XU Juan, JIANG Shujuan, XIA Li, ZHANG Yang, WANG Yikun, LI Zhongsheng, ZHANG Shiqi
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Renal protective effect and mechanism research of hypoxia inducible factor-1α inhibitor YC-1 in diabetic nephropathy mice [PDF]
Objective·To investigate the effect of hypoxia inducible factor-1α (HIF-1α) inhibitor YC-1 on the progression of diabetic nephropathy (DN) in mice and the potential mechanism.Methods·Ten-week-old male db/db mice (DN model) and their nondiabetic wild-type
FAN Ying +5 more
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Differences of Community Health Service Quality Evaluation in China and Abroad:a Systematic Review [PDF]
BackgroundIn China, the assessment of community health services has been increasingly valued as the development of such services advances, but relevant research is still at the exploratory stage. Therefore, establishing a community health service quality
ZHANG Qianqian, JIN Hua, YU Dehua
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【目的】了解广东省1型糖尿病(T1DM)患者糖尿病肾病(DN)的现况并探讨其危险因素?【方法】 通过广东省T1DM临床研究数据库登记2000年1月1日及以后就诊的T1DM患者人口学资料和临床资料,收集随访患者的全血及尿液标本进行糖化血红蛋白(HbA1c)及尿白蛋白/肌酐(UACR)的中心化检测?根据UACR将患者分为正常白蛋白尿组,微量白蛋白尿组及大量白蛋白尿组?用秩和检验和Logistic回归分析DN与各因素的相关性?【结果】 2010年8月至2011年3月共纳入814例患者,中位年龄29.4岁 ...
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Study of the correlation between ApoB/ApoA1 and vitreous hemorrhage secondary to diabetic retinopathy [PDF]
Objective To investigate the correlation between ApoB/ApoA1 and vitreous hemorrhage (VH) secondary to diabetic retinopathy (DR). Methods 187 patients with DR from August 2021 to December 2022 were recruited and divided into VH (n=96) and non-VH groups (n=
Dan Yujiao, Zhang Ling, Chen Bin
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Research progress in the role of gut microbiota in the pathogenesis and treatment of IgA nephropathy [PDF]
As the most common form of glomerulonephritis worldwide, IgA nephropathy (IgAN) is characterized by the diffuse deposition of immune complexes formed by glycosylation-deficient IgA1 (Gd-IgA1) and its specific antibodies (Gd-IgA1-IgG) in the glomerular ...
LI Junru, OUYANG Yan, XIE Jingyuan
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