Results 11 to 20 of about 6,137 (162)

Correlation of ACR and TcPO2 in diabetic kidney disease patients: A pilot study. [PDF]

open access: yesJ Diabetes, 2023
Highlights Transcutaneous oxygen pressure (TcPO2) could be used to assess microcirculation, which revealed endothelial injury. As endothelial injury is a cause of albuminuria in diabetic kidney disease (DKD), albuminuria and creatinine (ACR) might be employed to assess microcirculation in DKD patients in rural hospital where TcPO2 is not available. Our
Sun J   +7 more
europepmc   +2 more sources

Combined detection of urinary biomarkers noninvasively predicts extent of renal injury in patients with early diabetic kidney disease with kidney qi deficiency syndrome: A retrospective investigation

open access: yesThe Anatomical Record, Volume 306, Issue 12, Page 2945-2957, December 2023., 2023
Abstract Incipient diagnosis and noninvasive forecasts using urinary biomarkers are important for preventing diabetic kidney disease (DKD) progression, but they are also controversial. Previous studies have shown a potential relationship between urinary tubular biomarkers (UTBs) and traditional Chinese medicine (TCM) syndrome in patients with DKD. Thus,
Wei Wu   +11 more
wiley   +1 more source

Decreased in n‐3 DHA enriched triacylglycerol in small extracellular vesicles of diabetic patients with cardiac dysfunction 糖尿病合并心脏功能障碍患者细胞外小囊泡中n‐3 DHA 富集的三酰甘油减少

open access: yesJournal of Diabetes, Volume 15, Issue 12, Page 1070-1080, December 2023., 2023
Highlights Lipid profiles of small extracellular vesicles (sEVs) in patients with diabetes or diabetic cardiovascular disease are rarely reported. n‐3 docosahexaenoic acid (DHA)‐enriched triacylglycerol (TG) was found to decrease in sEVs from serum of patients with diabetic cardiovascular disease (DM‐CAD).
Wei Ding   +3 more
wiley   +1 more source

Fatty acid β‐oxidation and mitochondrial fusion are involved in cardiac microvascular endothelial cell protection induced by glucagon receptor antagonism in diabetic mice 脂肪酸β‐氧化和线粒体融合参与胰高血糖素受体拮抗剂对糖尿病小鼠心脏微血管内皮细胞的保护作用

open access: yesJournal of Diabetes, Volume 15, Issue 12, Page 1081-1094, December 2023., 2023
Highlights Glucagon receptor (GCGR) monoclonal antibody (mAb) improves cardiac function and attenuates microvascular damage in db/db mice. GCGR mAb ameliorates the oxidative stress of cardiac microvascular endothelial cells in diabetic mice. GCGR mAb counteracts the diabetes‐induced upregulation of carnitine palmitoyltransferase 1B, optic atrophy type ...
Peng Wang   +6 more
wiley   +1 more source

Associations of blood biomarkers with arterial stiffness in patients with diabetes mellitus: A population‐based study 糖尿病患者血液生物标志物与动脉硬化的关系: 一项基于人群的研究

open access: yesJournal of Diabetes, Volume 15, Issue 10, Page 853-865, October 2023., 2023
Highlights Few studies have investigated the association of large‐scale biomarkers and pulse wave velocity (PWV) among diabetic patients. This study investigates the relationships of serum laboratory tests with PWV and explored the associations between PWV and all‐cause mortality among diabetic patients.
Yong‐Qi Liang   +9 more
wiley   +1 more source

Protective effects of nattokinase against microvasculopathy and neuroinflammation in diabetic retinopathy 纳豆激酶对糖尿病视网膜病变微血管病变和神经炎症的保护作用

open access: yesJournal of Diabetes, Volume 15, Issue 10, Page 866-880, October 2023., 2023
Highlights Nattokinase rescued endothelial dysfunction and pericyte loss in the diabetic retina. Nattokinase attenuated diabetes‐induced retinal inflammation and neurodegeneration. High mobility group box 1 signaling was involved in nattokinase‐mediated retinal protection.
Zijing Huang   +11 more
wiley   +1 more source

Association between serum LDL‐C concentrations and risk of diabetes: A prospective cohort study 血清低密度脂蛋白胆固醇浓度与糖尿病风险之间的关联: 一项前瞻性队列研究

open access: yesJournal of Diabetes, Volume 15, Issue 10, Page 881-889, October 2023., 2023
Highlights Serum low‐density lipoprotein cholesterol (LDL‐C) levels were positively and significantly associated with a high risk of incident diabetes. Even in participants with normal LDL‐C levels (<130 mg/dL), a 1‐SD increase in LDL‐C levels was significantly associated with a higher risk of diabetes development.
Jiaojiao Huang   +13 more
wiley   +1 more source

Development and validation of a multivariable risk prediction model for identifying ketosis‐prone type 2 diabetes 酮症倾向2型糖尿病多变量风险预测模型的建立与验证

open access: yesJournal of Diabetes, Volume 15, Issue 9, Page 753-764, September 2023., 2023
Highlights Ketosis‐prone type 2 diabetes mellitus (T2DM) is a novel type of diabetes mellitus, distinguished from type 1 diabetes mellitus and T2DM. Its clinical characteristics are complex and there is a lack of auxiliary tools for differential diagnosis.
Jia Zheng   +7 more
wiley   +1 more source

Increased glutamate in type 2 diabetes in the Korean population is associated with increased plasminogen levels 韩国2型糖尿病患者谷氨酸升高与纤溶酶原水平升高有关

open access: yesJournal of Diabetes, Volume 15, Issue 9, Page 777-786, September 2023., 2023
Highlights Increased glutamate is associated with the development of diabetes. Glutamate increases plasminogen (PLG) levels through glutamate metabotropic receptor 5 activation with various insulin resistance‐related stresses. Glutamate inhibits the conversion of PLG to plasmin by increasing plasminogen activator inhibitor‐1.
Hyo Jung Lee   +7 more
wiley   +1 more source

The impact of health literacy interventions on glycemic control and self‐management outcomes among type 2 diabetes mellitus: A systematic review 健康素养干预对2型糖尿病患者血糖控制和自我管理结果的影响:一项系统综述

open access: yesJournal of Diabetes, Volume 15, Issue 9, Page 724-735, September 2023., 2023
Highlights Health literacy (H)L‐driven interventions were effective in controlling glycemic levels and improving diabetes self‐management outcomes. The level of glycemic control and self‐management skills were improved better through individual and telephone‐based intervention, respectively, in comparing group intervention.
Jamila Butayeva   +3 more
wiley   +1 more source

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