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Ecological Solutions and Evidence, Volume 6, Issue 3, July–September 2025.Over the past three decades, a large number of natural wild soybean populations have been declining inexplicably or even have disappeared and their distribution area has significantly decreased in China, and population losses continue unabated. Therefore, this study investigated 20 herbaceous communities of wild soybeans in various habitats in ...
Ke‐Jing Wang, Xiang‐Hua Li
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RNA 干扰 mPGES-1 基因对 K562/A 细胞增殖及凋亡的影响
Zhongshan Daxue xuebao. Yixue kexue ban, 2020 【目的】探讨RNA干扰膜结合型前列腺素E2合酶1（mPGES-1）对阿霉素耐药的人红白血病细胞株K562/A细胞增殖、凋亡及耐药性的影响及其可能的机制。【方法】通过RNA干扰技术抑制K562/A细胞中mPGES-1表达。分组：①未处理组（K562/A），②干扰后的阴性对照组（K562/A-NC），③干扰组（K562/A-KD），④干扰后加入外源性PGE2组（K562/A-KD+PGE2）；CCK-8法检测细胞活力；流式细胞术检测细胞凋亡；ELISA法检测PGE2浓度；Western blot检测蛋白水平。
邱梦 +7 more
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Experimental Study on the Effects of Ciji Hua’Ai BaoSheng Decoction on Cytokines of Tumor Chemotherapy Model Mouse with H22 Hepatoma Carcinoma Cells [PDF]
, 2015 背景：癌症是一类严重危害人类生命健康的致死性疾病。化疗(Chemotherapy)是癌症临床治疗的经典方法之一，但化疗药物无选择性杀伤肿瘤细胞的同时，也杀伤正常细胞，带来较严重的副作用，严重影响患者生存质量及预后。慈济化癌保生汤(CHBF)是导师王彦晖教授临床多年诊治癌症所创立的经验方，该方用于癌症患者化疗后的长期调理，具有提高生存质量，改善体质、降低复发率及延长生存期的作用。前期研究证实[1]：慈济化癌保生颗粒能延长移植瘤和腹水瘤化疗模型小鼠的生存期，有一定的抑制化疗后移植瘤生长的作用 ...
GUAN JIE LOY
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Journal of Animal Ecology, Volume 94, Issue 4, Page 745-759, April 2025.Our study reveals how top predators influence mammalian interaction networks by increasing complexity and redistributing interactions through indirect effects. These findings imply the important role of top predators in structuring communities, offering novel insights into the conservation and management of mammal communities in northeastern China ...
Wen She +5 more
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Dizhen xuebao我国地震地电场观测时的漏电干扰问题会影响到观测质量和地震监测效能。针对这一实际问题，本文提出了点源干扰源定位方法。该方法首先建立地表点源对地电场观测影响模型，根据模型计算点源对地电场观测的干扰幅度，然后求解干扰源相对于中心电极的位置。将定位方法应用于高邮地震台和汉王地震台实际干扰源排查工作中，定位结果与实际干扰源位置基本一致，测区外干扰源定位误差小于2%，测区内干扰源定位误差小于20 m，并对影响计算误差的因素进行了分析。两个台站的实际应用表明 ...
Yu Zhang +4 more
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Molecular mechanism of Receptor-Interacting Protein 3 (RIP3) Enhancing Type I Interferons Production [PDF]
, 2016 2009以来，随着受体相互作用蛋白3（RIP3）介导细胞坏死信号通路的发现，跟RIP3相关的功能研究逐渐成为细胞生物学领域的研究热点。我们最近的研究发现RIP3能够显著促进I型干扰素的分泌，特别是促进双链DNA（dsDNA）诱导的I型干扰素的分泌。然而，RIP3是否参与调控DNA病毒诱导的I型干扰素的产生，并且RIP3是如何促进I型干扰素的分泌的，目前还不清楚。本项目拟通过利用CRISPR-Cas9介导的基因敲除技术构建RIP3敲除的细胞系 ...
梁耀极
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Veterinary Dermatology, Volume 35, Issue 6, Page 736-744, December 2024.Background – Topical therapy is preferred for otitis externa (OE) in dogs, and otic products commonly contain glucocorticoids that can be systemically absorbed and possibly interfere with diagnostic tests such as intradermal testing (IDT). Hypothesis/Objectives – To determine the effect of a long‐lasting otic solution containing mometasone furoate (MF)
Jennifer L. Clegg +2 more
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Veterinary Dermatology, Volume 35, Issue 6, Page 595-604, December 2024.Background – Mycobacterium cell wall fraction (MCWF) is derived from nonpathogenic Mycobacterium phlei and is used as an immunomodulatory compound in clinical practice, yet its mode‐of‐action requires further research. Objective – To evaluate the host response to MCWF in canine peripheral blood mononuclear cells (PBMCs) by using enzyme‐linked ...
Robert Ward +9 more
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慢性HCV感染者外周血单个核细胞IL-18和IFNAR1检测的临床意义
Zhongguo shiyan zhenduanxue, 2006 目的分析慢性丙肝（CHC）患者外周血单个核细胞（PBMC）白细胞介素18（IL18）mRNA的诱导表达及α干扰素受体1（IFNαreceptor1,IFNAR1）表达,评价慢性丙肝患者PBMC细胞免疫功能。方法脂多糖（LPS）体外刺激正常对照组和慢性丙型肝炎病毒（HepatitisCvirus,HCV）感染组病人PBMC,RTPCR检测干扰素治疗前后PBMCIL18mRNA水平的变化。同时RTPCR检测不同组PBMCIFNAR1mRNA水平的差异。结果治疗前干扰素应答组病人（n=12）和无应答组病人（n=
卢银平, 董继华, 刘朝, 管世鹤
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Gaoya dianqi, 2022 随着柱式开关、环网柜等一二次融合配电开关设备的推广应用，对配电开关设备入网检测方案和关键影响因素分析需求迫切。文中根据一二次融合配电开关设备的结构组成原理，分析环境温度、电磁干扰和局部放电等因素对一二次融合设备可靠性和准确性的影响原因。利用高低温环境模拟箱、雷电冲击发生装置和局放测试仪等设备实验研究上述因素对配电开关一二次融合影响规律，提出串联滤波电路用于提高设备的抗强电磁干扰能力，降低了互感器输入端高频干扰的影响，为配电开关一二次融合入网检测和关键指标考核提供参考。
徐铭铭 +4 more
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