目的探索人子宫内膜间质细胞纤维化的发生机制,并评估雷洛昔芬(Raloxifene,RAL)阻滞该进程的潜力。方法采用10 ng/mL 转化生长因子β1(Transforming Growth Factor-β,TGF-β1)诱导人子宫内膜间质细胞(human endometrial mesenchymal stromal cells,hESCs)发生纤维化,为TGF-β1组;TGF-β1诱导hESCs后加入RAL,为RAL组;对照组仅加入等量生理盐水。MTT法检测细胞增殖;划痕实验评估细胞迁移;RT ...
臧欢欢 +5 more
doaj
[Application of Kartogenin in cartilage tissue engineering]. [PDF]
Jiang J, Zhang S, Lu W.
europepmc +1 more source
【目的】 初步探讨地塞米松导致VSMCs钙化的分子机制65377; 【方法】 用地塞米松(Dex)诱导血管平滑肌细胞(VSMCs),检测其双链蛋白聚糖(BGN)的表达65377;并通过10-8 mol/L Dex诱导BGN重组腺病毒Ad/BGN感染的VSMCs,分别检测VSMCs钙化程度,BGN65380;osteocalcin65380;cbfa165380;骨形态生成蛋白4(BMP4)的表达65377;实验分4组(n = 3):Ad/Bgl-BGP组:用空载体Ad/Bgl感染细胞;Ad/BGN ...
doaj
[Liver-bone axis: novel mechanisms and strategies for MAFLD regulation]. [PDF]
Wang YW, Yan XZ, You H, Yang AT.
europepmc +1 more source
[The role and mechanism of chemokine network in promoting osteoarthritis progression by regulating synovial macrophage heterogeneity]. [PDF]
Lin Y, Wu L, Chen Q, Shen B.
europepmc +1 more source
[A case of segmental atrophy of the liver in children]. [PDF]
Qiu YL, Mao Y, Lu CL.
europepmc +1 more source
Effects of hirudin for the thrombin-induced expression of adhesive molecules in neutrophils and human umbilical vein endothelial cells [PDF]
Cui, LQ +4 more
core
[Expression of the melanoma 2-mediated pyroptosis pathway in peripheral blood mononuclear cells of patients with idiopathic inflammatory myopathies]. [PDF]
Chu J +6 more
europepmc +1 more source
食管黏膜下肿瘤(submucosal tumors, SMTs)是发生于黏膜下层或固有肌层的突起性病变,被完整的黏膜上皮所覆盖[1]。在已知的食管SMTs中,平滑肌瘤占比最高,达到70%~80%[2],间质瘤约占5%。食管SMT组织病理学诊断为低分化鳞状细胞癌十分罕见。在这里,我们报告了一例食管SMT患者,术后组织病理学检查确诊为低分化鳞状细胞癌。此病例提醒我们,食管SMTs有可能是鳞状细胞癌的一种表现,此类型的SMT预后比其他类型差。
周世平, 李蓥
doaj
[Rosa laevigata Michx. inhibits pulmonary arterial smooth muscle cell proliferation in hypertension by modulating the Src-AKT1 axis]. [PDF]
Yang Z +6 more
europepmc +1 more source

