目的检测微小RNA-92(microRNA-92,miR-92)在上皮性卵巢癌患者及健康人血清中的表达,分析miR-92与上皮性卵巢癌(epithelial ovarian cancer,EOC)病人的分期及预后的关系,为寻找一种新型的、无创的用于EOC患者早期筛查及判断预后的标志物提供理论依据。方法采用实时定量PCR(qRT-PCR)的方法检测50例EOC患者和50例健康人群血清中miR-92表达,应用ROC曲线评价其临床诊断价值,并对miR-92的表达与临床病理特征之间的相关性进行分析 ...
郭凤军 +4 more
doaj
[MicroRNA and Lung Cancer: A Mini Review]. [PDF]
Tuo L, Chu X, Sha S, Zhang X.
europepmc +1 more source
[miR-302a-3p targeting lysosomal-associated membrane protein 5 inhibits the invasion and metastasis of oral squamous cell carcinoma]. [PDF]
Yu L +10 more
europepmc +1 more source
[Research advances on the role of microRNA engineered exosomes in diabetic wounds]. [PDF]
Jian XC, Deng CL.
europepmc +1 more source
尿外泌体非编码RNA在糖尿病肾病发病机制及诊断中的最新研究进展 附视频
糖尿病肾病(diabetic kidney disease,DKD)如今占所有导致终末期肾病(end-stage renal disease ESRD)原发病的近50%[1]。目前糖尿病肾病的诊断及分期主要依靠尿微量白蛋白的检测,其缺点是敏感性和特异性相对较低,而肾穿刺活检术则操作风险较高,尚缺少采集程序无创性的理想检测标志物。外泌体是直径范围40~160nm被脂质双层膜包裹的囊泡,广泛分布于血液、尿液等体液中。尿液中的外泌体是一种易采集的非侵入性生物标志物 ...
doaj +2 more sources
[<i>Poria cocos</i> polysaccharide alleviates cyclophosphamide-induced intestinal barrier dysfunction and inflammation in mice by modulating gut flora]. [PDF]
Zhang Y +10 more
europepmc +1 more source
[Human umbilical cord mesenchymal stem cell grafting alleviates inflammatory response in type 1 diabetic mice by suppressing M1 macrophage polarization through Chi3l1]. [PDF]
Liu X, Xu Y, Sheng H, Liu H.
europepmc +1 more source
[Role of microRNA-17-5p in the pathogenesis of pediatric nephrotic syndrome and related mechanisms]. [PDF]
Zhang YR +4 more
europepmc +1 more source
[Research progress on extracellular vesicles derived from platelet-rich plasma in tissue repair and regeneration]. [PDF]
Han J, Cheng B.
europepmc +1 more source

