海马干细胞来源的外泌体对血管性痴呆大鼠学习记忆能力改善作用及其机制探究 附视频
Zhongguo shiyan zhenduanxue目的 分析海马干细胞来源的外泌体对血管性痴呆大鼠学习记忆能力改善作用及其机制。方法 取新生SD大鼠海马组织，提取海马干细胞外泌体。成年特殊清洁级(SPF)健康雄性SD大鼠90只，随机分为假手术组、模型组及外泌体组，每组30只，检测各组大鼠学习记忆能力、氧化应激因子水平、海马组织病理学变化、海马组织因子、脑微血管密度以及凋亡相关因子变化。结果 透射显微镜观察到海马干细胞来源外泌体结构呈圆形或椭圆形杯状结构的小囊泡，其结构完整，直径50～100 nm之间；特异性标记蛋白CD9、CD63表达阳性 ...
doaj +2 more sources
吗啡对顺铂诱导的鼻咽癌CNE-2细胞裸鼠 移植瘤生长抑制作用的影响
Zhongshan Daxue xuebao. Yixue kexue ban, 2010 【目的】 以人鼻咽癌CNE-2细胞裸鼠移植瘤为模型,探讨吗啡对顺铂抑制肿瘤生长作用的影响及其机制65377;【方法】 建立CNE-2细胞裸鼠移植瘤模型20只,随机分为4组,对照组,单纯顺铂用药组65380;单纯吗啡用药组和吗啡联合顺铂用药组,每组5只65377;吗啡5 mg/kg每天给药1次,顺铂3 mg/kg每3 d给药2次,均为腹腔注射65377;用药14 d后处死动物,完整剥离肿瘤,记净瘤质量65377;TUNEL染色计算细胞凋亡数,免疫组化染色检测肿瘤组织Bax,Bcl-2,cleaved ...
doaj
[Research progress in diagnosis and treatment of non-tumorous salivary gland diseases]. [PDF]
Beijing Da Xue Xue Bao Yi Xue BanCong X, Su J, Wu L, Ding C, Li W, Yu G.
europepmc +1 more source
[Endodontic retreatment of a maxillary second molar with chronic apical periodontitis and separated instrument: A case report]. [PDF]
Beijing Da Xue Xue Bao Yi Xue BanZang H, Liang Y.
europepmc +1 more source
[A case of segmental atrophy of the liver in children]. [PDF]
Zhonghua Gan Zang Bing Za ZhiQiu YL, Mao Y, Lu CL.
europepmc +1 more source
[Determination of 30 homologues of phosphatidylcholines and lysophosphatidylcholines in human serum by liquid chromatography-tandem mass spectrometry and their correlation analysis with coronary artery disease]. [PDF]
Se PuLi WY +6 more
europepmc +1 more source
糖尿病视网膜病变UWFA量化分析及其与糖尿病黄斑水肿的关联研究
Zhongshan Daxue xuebao. Yixue kexue ban目的量化糖尿病视网膜病变（DR）患者超广角荧光素眼底血管造影（UWFA）图像中不同视网膜区域的病灶参数，探讨其与中心凹受累的糖尿病黄斑水肿（CI-DME）的相关性。方法回顾性分析2022年6月至2024年6月于广东省人民医院初诊的76例DR患者（共101眼）在同一天拍摄的UWFA及光学相干断层扫描（OCT）图像。根据OCT测量的中央视网膜厚度（CST）将患眼分为CI-DME组与非CI-DME组。手动标注UWFA图像中微血管瘤、无灌注区、渗漏区、视盘和中心凹，量化计算黄斑区、后极部、中周部 ...
梁慧琳, 徐智聪, 张良, 曹丹
doaj
[Medical treatment standards for emergency burn wounded (2025 edition)]. [PDF]
Zhongguo Xiu Fu Chong Jian Wai Ke Za ZhiNational Health Commission Of The People's Republic Of China.
europepmc +1 more source
[Indole-3-acetic acid alleviates <i>Cryptococcus neoformans</i>-induced pyroptosis in cerebral microvascular endothelial cells by regulating stress granule-mediated NLRP3 inflammasome activation]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoChen J +5 more
europepmc +1 more source
[Management of accidental tooth root displacement into the mandibular canal during tooth extraction]. [PDF]
Hua Xi Kou Qiang Yi Xue Za ZhiSu L, Zhao J.
europepmc +1 more source