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诊断轻链型心脏淀粉样变的超声心动图新进展

open access: yesZhongguo shiyan zhenduanxue
轻链型心脏淀粉样变(Amyioid light-chain cardiac amyloidosis,AL-CA)是一种浸润性限制型心肌病,是由浆细胞异常增殖产生单克隆免疫球蛋白轻链,其错误折叠形成不可溶的淀粉样蛋白纤维沉积于心肌细胞间质和血管周围,导致心脏结构和功能的素乱。其临床表现无特异性,病程进展迅速,预后极差。因此,早期诊断并及时启动治疗意义重大。超声心动图作为诊断 AL-CA 的首选影像学手段,通过斑点追踪技术、压力-应变环分析、多参数评估、衍生参数及人工智能的辅助,为临床提供了更多敏感指标 ...
张赫展, 付启航, 张冬雪, 徐卉
doaj  

[Advances on efficacy and mechanisms of acid fibroblast growth factor for promoting injured tissue repair]. [PDF]

open access: yesZhongguo Xiu Fu Chong Jian Wai Ke Za Zhi
Zhu F   +5 more
europepmc   +1 more source

[Research progress on the quercetin target role and signaling pathway in anti-liver fibrosis]. [PDF]

open access: yesZhonghua Gan Zang Bing Za Zhi
Zhao RQ   +9 more
europepmc   +1 more source

[The potential role of calnexin in the activation of cardiac fibroblasts]. [PDF]

open access: yesSheng Wu Yi Xue Gong Cheng Xue Za Zhi, 2020
Tian G   +5 more
europepmc   +1 more source

己酮可可碱在阿霉素心肌病大鼠中的抗炎症作用

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 2016
摘 要: 【目的】探讨己酮可可碱在阿霉素心肌病大鼠模型中的作用及机制研究? 【方法】 6周龄雄性SD大鼠30只,随机分为3组:①生理盐水组;②阿霉素(ADR)组;③阿霉素(ADR)+己酮可可碱(PTX)组?动物药物处理3周后,取大鼠的心脏组织作病理学分析并提取RNA检测炎症因子TNF-α?IL-1β?IL-10的表达情况;同时研磨心肌组织,提取蛋白,ELISA检测TNF-α?IL-1β?IL-10的表达情况?并且采用高频多普勒超声检测评价实验中各组心脏收缩功能?
doaj  

[Analysis of serum lipidomics for a spontaneous hepatic fibrosis mouse model]. [PDF]

open access: yesZhonghua Gan Zang Bing Za Zhi
Zheng JH, Wu K, Wang K, Tang N.
europepmc   +1 more source

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