Results 1 to 10 of about 3,939 (118)
Rare Metals, Volume 45, Issue 2, February 2026.ABSTRACT This study introduces novel nonequiatomic TiZrCoCrMoCux (x = 0, 5, 10; at%) medium‐entropy alloys (MEAx) tailored for orthopedic implants, synergistically combining the biocompatibility of Ti‐based alloys, the wear resistance of CoCrMo alloys, and the antibacterial/osteogenic attributes of Cu. The alloy's microstructure, mechanical properties,
Hang Yu +9 more
wiley +1 more source
Advanced Science, Volume 13, Issue 3, 14 January 2026.Conceptual diagram and schematic illustration of microenvironmental changes in individuals with ASBO before and after treatment. BMSC@Gel therapy transforms the ASBO microenvironment from an inflammatory, fibrotic state with aberrant matrix deposition and barrier dysfunction to a regenerative state with reduced inflammation and improved structural ...
Lihong Zheng * +7 more
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2017 MicroRNA（微小RNA,miRNA）是一类大小约19-25nt的短链非编码RNA,人类已发现1000多种miRNA,参与调节了人60%以上的人类基因[1]。MiRNA由RNA20polymeraseⅡ转录成较长的初级产物pri-miRNA,然后在Drosha和DGCR8酶的作用下,剪切为约70nt并具有独特发卡结构的premiRNA ...
王小昆, 张玉成, 吴晓冬
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Rare Metals, Volume 45, Issue 1, January 2026.ABSTRACT Articular cartilage regeneration remains a significant challenge because of its limited intrinsic healing capacity and the inadequacy of conventional treatments for restoring structural and functional integrity. In this study, a novel injectable composite hydrogel scaffold was designed to mimic the extracellular matrix (ECM) of native ...
Zhong‐Lian Wu +13 more
wiley +1 more source
Zhongshan Daxue xuebao. Yixue kexue ban, 2002 【目的】探讨一氧化氮(NO)在舌鳞癌血管生成中的作用。【方法】原位杂交检测68 例舌鳞癌活检组织常规石 蜡包埋标本中诱导型一氧化氮合酶(iNOS)m RNA 的表达, 分别以血管内皮生长因子(VEGF)多克隆抗体、Ⅷ 因子单克隆抗体 免疫组化检测上述舌鳞癌标本中VEGF 的表达和微血管密度(M VD)。【结果】①舌鳞癌iNOS mRNA 表达阳性组微血管密度 显著高于阴性组(P
曾曙光
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Veterinary Dermatology, Volume 36, Issue 5, Page 668-678, October 2025.Background – Erythemato‐ceruminous otitis externa (ECOE) is commonly associated with Malassezia spp. and microbial imbalance. Hypothesis/Objective – To assess the clinical performance of an ear cleaner in dogs suffering from ECOE associated with Malassezia spp. overgrowth and to measure its impact on the microbiota. Conclusions and Clinical Relevance –
Amaury Briand +11 more
wiley +1 more source
Implications of Tobacco Use on Pathogen‐Driven Diseases: A Public Health and Policy Perspective
World Medical &Health Policy, Volume 17, Issue 3, Page 468-474, September 2025.ABSTRACT The tobacco epidemic remains one of the most significant global public health challenges, responsible for over 8 million deaths annually, with a substantial portion occurring among non‐smokers exposed to second‐hand smoke. While cigarette smoking remains the most prevalent form of tobacco use worldwide, the rise of electronic nicotine delivery
Nadine Kabbani, James L. Olds
wiley +1 more source
Updated insights into the molecular pathogenesis of canine atopic dermatitis
Veterinary Dermatology, Volume 36, Issue 4, Page 375-384, August 2025.Abstract Atopic dermatitis (AD) is a common and chronic inflammatory skin disease with frequent relapses. The genomics revolution has greatly contributed and revolutionised our knowledge of human AD; understanding the molecular skin fingerprint of AD and associated pathogenic immune pathways has led to preclinical assessments of several novel ...
Frane Banovic
wiley +1 more source
Veterinary Dermatology, Volume 36, Issue 1, Page 14-23, February 2025.Background – Bacterial identification and antimicrobial susceptibility testing is an important step in timely therapeutic decisions for canine superficial bacterial folliculitis (SBF), commonly caused by Staphylococcus pseudintermedius. Next‐generation sequencing (NGS) offers the appeal of potentially expedited results with complete detection of ...
Kimberly Smart +4 more
wiley +1 more source
microRNA-218通过靶向HOXA10抑制肝癌细胞的实验研究
Zhongguo shiyan zhenduanxue, 2019 微小RNA(microRNA,miRNAs)是一类长约22个核苷酸的单链非编码RNA,通过与靶mRNAs完全或不完全互补配对,导致靶基因降解或抑制其翻译,从而在基因的表达调控中发挥着重要作用。研究表明microRNAs参与了肝癌的发生、发展和侵袭转移的全过程[1,2]但是有关miR-218在肝癌(HCC)的生物学功能仍然未知 ...
肖钟迪, 王雅丽, 付凯
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