Results 11 to 20 of about 3,939 (118)
微粒体在缺血性卒中的作用 The Role of Microparticles in Ischemic Stroke
Zhongguo cuzhong zazhi, 2019 【摘要】 在血管内皮功能障碍、急慢性血管炎症和高凝状态下均可发现由血小板、白细胞和内皮细胞释放的微粒体。不同种类的微粒体在缺血性卒中病理过程中的作用有所不同：缺血性卒中患者外周血白细胞微粒升高，高水平的白细胞微粒体能加重血管内皮细胞损伤，血浆中长期及高水平的血小板微粒体可诱导微血管血栓形成。另外，不同种类的微粒体均能反映血管内皮损伤的程度，诱导内皮细胞功能失调，加重内皮功能障碍，同时微粒体中携带的信使RNA和微小核糖核酸等能促进内皮细胞增殖，促进动脉粥样硬化斑块内新生血管生成，使斑块更易破裂出血。
周蕾，吴冬雨，姚小梅，时彦莹，朱宪策，黄晶，王春雪，张宁
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主动脉夹层患者血清中miR-20、miR-15a水平与预后关系
Zhongguo shiyan zhenduanxue, 2021 目的探究微小RNA-20(miR-20)、微小RNA-15a(miR-15a)在主动脉夹层患者血清中的表达水平及两者与预后的关系。方法选取2015年4月至2018年7月于本院确诊的109例主动脉夹层患者为研究对象,称患病组,并将同期106例健康体检者作为对照,为健康组。以实时荧光定量PCR法检查所有受试者血清中miR-20、miR-15a表达水平;分析两组不同预后患者一般资料及血清中miR-20、miR-15a水平;采用Logistic回归分析影响主动脉夹层预后的因素;利用受试者工作特征曲线(ROC ...
李亮 +6 more
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Harnessing Trace Elements: Novel Radiosensitization Strategies for Enhanced Cancer Radiotherapy
Rare Metals, Volume 45, Issue 6, June 2026.ABSTRACT Radiotherapy (RT) is one of the core methods of comprehensive cancer treatment. Globally, more than 40% of cancer patients rely on radiotherapy to achieve tumor control, cure or palliative relief. However, radiation resistance, immunosuppression and normal tissue injury limit its clinical application.
Yuhuan Zhang +6 more
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基于环境
Haiyang yu huzhao海山遍布大洋海底，由于其特殊海底地形和水文动力环境，孕育了丰富且特殊的生物群落。采用环境RNA技术分析西太平洋M4浅水海山区真核微生物的多样性和分布，并与环境DNA技术检获的结果进行比较，揭示二者的异同。研究发现，RNA和DNA技术检获的表层和DCM层群落结构相似，在200 m以深的水层中群落结构差异较大。共甲藻纲的相对丰度在DNA数据中占比高于RNA数据，因此可能被基于eDNA的技术高估；而甲藻纲和金藻纲则相反，存在被低估的可能性。通过真核微生物与细菌的共现网络 ...
尹 婷婷 +3 more
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Rare Metals, Volume 45, Issue 6, June 2026.ABSTRACT The poor soft tissue integration around titanium implants creates a microgap that serves as a pathway for pathogen invasion, resulting in infection, inflammation, and the progression of peri‐implantitis. As the implant’s transmucosal component, the abutment determines the degree of peri‐implant soft tissue attachment.
Xuan Li +7 more
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Veterinary Dermatology, Volume 37, Issue 3, Page 353-364, June 2026.ABSTRACT Background Canine atopic dermatitis (cAD) is a multifactorial, inherited skin disease, estimated to affect ≤ 15% of dogs. Studies of skin messenger mRNA in cAD currently use invasive methods, including blood sampling and biopsy collection, whilst advances in human atopic dermatitis study methodology have demonstrated reliable use of minimally ...
Xavier Langon +5 more
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Veterinary Dermatology, Volume 37, Issue 3, Page 375-385, June 2026.ABSTRACT Background Advances in transcriptomics have driven the demand for minimally invasive, reproducible and high‐yield skin sampling methods, particularly for studying inflammatory skin diseases in companion animals. Hypothesis/Objectives We tested tolerability, feasibility and RNA quantity and quality of three minimally invasive skin sampling ...
Ina Herrmann +2 more
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Functional Ecology, Volume 40, Issue 5, Page 1428-1442, May 2026.Read the free Plain Language Summary for this article on the Journal blog. Abstract The stoichiometric imbalance caused by nitrogen (N) deposition typically exacerbates phosphorus (P) limitation in plants. However, it remains unclear whether this effect extends to soil microbes, particularly those in the rhizosphere.
Jipeng Wang +5 more
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Zhongguo shiyan zhenduanxue, 2010 目的探讨膀胱癌中微小RNA-21和肿瘤抑素表达与临床病理特征之间的关系。方法采用SABC法对98例膀胱癌患者分别进行微小RNA-21和肿瘤抑素的免疫组化染色,其与肿瘤临床分期和细胞分级间的关系及微小RNA-21和肿瘤抑素在瘤细胞中的共表达情况。结果膀胱癌患者中微小RNA-21和肿瘤抑素的阳性表达率分别是69.4%和43.9%。与浅表性和分化较好的膀胱癌相比,侵袭性和分化差的癌细胞中微小RNA-21表达上调明显,而肿瘤抑素表达则显著下调,组间比较 ...
李然伟 +5 more
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Rare Metals, Volume 45, Issue 4, April 2026.ABSTRACT Constructing a porous scaffold with the essential features of natural cancellous bone, including structural architecture and biochemical cues, is one of the pivotal factors for effective bone regeneration. In this study, a biomimetic composite porous Gelatin fibrous scaffold (SrHA/Gelatin) incorporating ultralong strontium‐doped hydroxyapatite
Yin‐Chuan Wang +8 more
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