Results 21 to 30 of about 3,897 (156)

Tolerability and Feasibility of Minimally Invasive Canine Skin Sampling: Excellent Tolerability Meets Transcriptomic Challenges

open access: yesVeterinary Dermatology, Volume 37, Issue 3, Page 375-385, June 2026.
ABSTRACT Background Advances in transcriptomics have driven the demand for minimally invasive, reproducible and high‐yield skin sampling methods, particularly for studying inflammatory skin diseases in companion animals. Hypothesis/Objectives We tested tolerability, feasibility and RNA quantity and quality of three minimally invasive skin sampling ...
Ina Herrmann   +2 more
wiley   +1 more source

基于环境RNA研究西太平洋浅水海山区真核微生物多样性及其与细菌的关系

open access: yesHaiyang yu huzhao
海山遍布大洋海底,由于其特殊海底地形和水文动力环境,孕育了丰富且特殊的生物群落。采用环境RNA技术分析西太平洋M4浅水海山区真核微生物的多样性和分布,并与环境DNA技术检获的结果进行比较,揭示二者的异同。研究发现,RNA和DNA技术检获的表层和DCM层群落结构相似,在200 m以深的水层中群落结构差异较大。共甲藻纲的相对丰度在DNA数据中占比高于RNA数据,因此可能被基于eDNA的技术高估;而甲藻纲和金藻纲则相反,存在被低估的可能性。通过真核微生物与细菌的共现网络 ...
尹 婷婷   +3 more
doaj   +1 more source

Advances in epigenetic mechanisms of lead toxicity [PDF]

open access: yes
Lead is a ubiquitous toxic heavy metal and one of the earliest and most widely used heavy metal elements in human history. Due to its non-degradable nature in the environment and its long biological accumulation effects (lasting up to 30‒50 years) in the
YAN Chonghuai, ZHANG Xinxin
core   +1 more source

Nitrogen deposition does not exacerbate phosphorus limitation of rhizosphere microbes in subalpine forests

open access: yesFunctional Ecology, Volume 40, Issue 5, Page 1428-1442, May 2026.
Read the free Plain Language Summary for this article on the Journal blog. Abstract The stoichiometric imbalance caused by nitrogen (N) deposition typically exacerbates phosphorus (P) limitation in plants. However, it remains unclear whether this effect extends to soil microbes, particularly those in the rhizosphere.
Jipeng Wang   +5 more
wiley   +1 more source

Cancellous Bone‐Like Sr‐Doped Hydroxyapatite/Gelatin Porous Scaffolds With Nanofibrous Architecture and Ion Release for Promoting Osteogenesis

open access: yesRare Metals, Volume 45, Issue 4, April 2026.
ABSTRACT Constructing a porous scaffold with the essential features of natural cancellous bone, including structural architecture and biochemical cues, is one of the pivotal factors for effective bone regeneration. In this study, a biomimetic composite porous Gelatin fibrous scaffold (SrHA/Gelatin) incorporating ultralong strontium‐doped hydroxyapatite
Yin‐Chuan Wang   +8 more
wiley   +1 more source

Multi‐barcoding‐based species identification using a hierarchical attention network with staged curriculum learning

open access: yesMethods in Ecology and Evolution, Volume 17, Issue 4, Page 1143-1160, April 2026.
Abstract DNA barcode‐based species identification has become pivotal in biodiversity research. Current barcoding‐based deep learning methods have advantages in species identification but exhibit significant limitations. By using COI barcoding alone, previous studies were unable to fully capture species identification features. Prior methods showed that
Bin Ye   +4 more
wiley   +1 more source

Genomic responses to increased temperature and pollinator selection in Brassica rapa L.

open access: yesNew Phytologist, Volume 250, Issue 2, Page 1231-1247, April 2026.
Summary Rapid environmental change reshapes both abiotic stress and biotic interactions, yet it remains unclear how these combined forces structure plants' genomic adaptation. In particular, the joint influence of temperature and pollinator identity, two ecological axes undergoing simultaneous global shifts, has rarely been quantified at genomic ...
Yanqian Ding, Florian P. Schiestl
wiley   +1 more source

微小RNA-21和肿瘤抑素在膀胱癌中的表达及其相关性的研究

open access: yesZhongguo shiyan zhenduanxue, 2010
目的探讨膀胱癌中微小RNA-21和肿瘤抑素表达与临床病理特征之间的关系。方法采用SABC法对98例膀胱癌患者分别进行微小RNA-21和肿瘤抑素的免疫组化染色,其与肿瘤临床分期和细胞分级间的关系及微小RNA-21和肿瘤抑素在瘤细胞中的共表达情况。结果膀胱癌患者中微小RNA-21和肿瘤抑素的阳性表达率分别是69.4%和43.9%。与浅表性和分化较好的膀胱癌相比,侵袭性和分化差的癌细胞中微小RNA-21表达上调明显,而肿瘤抑素表达则显著下调,组间比较 ...
李然伟   +5 more
doaj  

Hybrid Probiotic Hydrogel With Curcumin‐Loaded MnO2 Nanoparticles Enhances Diabetic Wound Healing Through Multimodal Microenvironmental Regulation

open access: yesRare Metals, Volume 45, Issue 3, March 2026.
ABSTRACT Skin wound injuries are often accompanied by bacterial infections and severe inflammation. Especially, M1‐type macrophages at the wound site can trigger a cascade of inflammatory responses, mediating a vicious cycle of inflammation. Meanwhile, hypoxia further exacerbates vascular damage and constriction in the wound microenvironment, thereby ...
Xianfeng Wang   +6 more
wiley   +1 more source

An Ultrasmall Strontium‐Loaded Polydopamine Nanoformulation for Near‐Infrared‐Enhanced Periodontitis Therapy via Photodynamic Gas‐Promoted Antibacterial and Bone Repair

open access: yesRare Metals, Volume 45, Issue 3, March 2026.
ABSTRACT Periodontitis is a chronic infectious oral disease triggered by periodontopathogenic bacteria, resulting in the progressive inflammation and destruction of the tissues surrounding teeth. To achieve reprogramming of the infectious microenvironment for periodontitis therapy, a nanoformulation was proposed by loading polydopamine (PDA) with ...
Hao Liang   +14 more
wiley   +1 more source

Home - About - Disclaimer - Privacy