Forensic Analysis of 43 Medical Disputes Caused by Death after Cardiac Surgery [PDF]
, 2021 Objective To explore the causes and characteristics of medical disputes caused by death after cardiac surgery and to analyze the pathological changes after cardiac surgery and the key points of forensic anatomy, thus to provide pathological evidence for ...
DAI Yun- da, CHEN Yan- chang, SHI Rui- juan, et al.
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Zhongguo cuzhong zazhi, 2023 儿童卒中是临床常见的危急症，是儿童致残和死亡的主要原因之一，病因复杂多样，其中心源性卒中不容忽视。三尖瓣下移畸形是一种少见的先天性心脏病，主要累及三尖瓣和右心室，少数可合并房间隔缺损或卵圆孔未闭引起矛盾栓塞，导致心源性卒中发生。本文报道1例由三尖瓣下移畸形合并房间隔缺损引起儿童卒中的病例，超声心动图技术有助于该类疾病的明确诊断、严重度评估以及其他异常的识别。 Abstract: Childhood stroke is a common critical disease, and is one of
周怡希，李永佳，兰亭玉，程令刚，何文，杜丽娟
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Effect of potential pathogenic gene PDX1 variants of total anomalous pulmonary venous connection on its gene function [PDF]
, 2023 Objective·To explore the possible pathogenic gene of total anomalous pulmonary venous connection (TAPVC) by whole exon sequencing and verify its function.Methods·One hundred TAPVC children (case group) and one hundred and twenty healthy children (control
FENG Weiqi +4 more
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Role of oxidative stress in trichloroethylene-induced toxicity [PDF]
, 2022 Trichloroethylene (TCE) is a common industrial organic solvent and environmental contaminant. People are exposed to TCE through occupational contact or environmental pollution, which leads to serious human health hazards.
Jinfeng ZHAO +4 more
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Bioinformatics analysis of pathological mechanism of degenerated tendon via stress deprivation [PDF]
, 2023 Objective·To explore relevant molecular mechanisms of the stress deprivation model of newborn rats by using bioinformatics analysis.Methods·A total of 60 SD rats (10 d post-natal) were enrolled in the study.
LI Qinglin, LIU Wei, WANG Wenbo
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Perfluorooctanoic acid induces abnormal heart development via aryl hydrocarbon receptor-mediated oxidative stress and apoptosis in zebrafish larvae [PDF]
BackgroundIn recent years, a growing number of studies have indicated that perfluorooctanoic acid (PFOA) exposure can impact heart development, though the specific mechanisms remain elusive. The aryl hydrocarbon receptor (AHR) is a critical environmental
Kang WANG +4 more
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四腔心与三血管气管切面联合HD-flow筛查早孕期胎儿心血管畸形的应用价值
Zhongshan Daxue xuebao. Yixue kexue ban, 2022 目的评估在未经选择人群中应用四腔心切面（Four-chamber view，4CV）与三血管气管切面（3VTV）联合高分辨率血流显像技术（HD-flow）筛查早孕期（11~13+6周）胎儿心血管畸形的诊断价值。方法2018年5月至2019年12月期间，在我院进行早孕期（11~13+6周）超声检查的胎儿1 145例，应用HD-flow对胎儿4CV、3VTV进行观察分析，记录检查结果和妊娠结局，通过对照引产后尸解或出生后超声心动图诊断结果，比较以上两个切面及联合切面筛查早孕期胎儿心血管畸形的敏感性、特异性 ...
黄羽君 +5 more
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Effects of hexabromocyclododecane (HBCD) on cardiac development in zebrafish embryos (Danio rerio): the mechanisms involved [PDF]
, 2015 六溴环十二烷（1,2,5,6,9,10-Hexabromocyclododecane，HBCD）是被运用最广泛的阻燃剂之一，在全球的用量仅次于四溴双酚A和多溴联苯醚。HBCD具有持久性、生物累积性和生物放大效应，因而被定义为持久性有机污染物（persistentorganicpollutants，POPs）。已有研究表明HBCD具有发育毒性、神经毒性、内分泌毒性和生殖毒性，但对心脏发育毒性的研究十分有限，尤其缺乏对心脏发育毒性机制的研究。本研究以斑马鱼和H9C2细胞系为实验模型，采用低浓度HBCD（0 ...
吴美芳
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Ultrasound in Obstetrics &Gynecology, Volume 66, Issue 2, Page 200-209, August 2025.Abstract Objectives Neonates with critical congenital heart disease (CCHD) are at risk for adverse early brain development and long‐term neurodevelopmental sequelae. Insulin‐like growth factor‐1 (IGF‐1) and insulin‐like growth factor binding protein‐3 (IGFBP‐3) are essential contributors to brain growth and maturation.
M. Nijman +33 more
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Prenatal Exposure to Airborne Particulate Matter on the Development of Heart in Rat Fetus [PDF]
, 2015 大气颗粒物（ParticulateMatter，PM）是指悬浮在大气中的固体、液体颗粒物的总称。不同来源的颗粒物形成条件不同，其粒径分布、化学组成也不同。目前国际公认的对人类健康危害较大且研究较多的大气颗粒污染物是PM2.5（FineParticulateMatter）和PM10（InhalableParticulateMatter）[1]。越来越多的证据表明，PM严重威胁着人体的健康，更对孕妇及胎儿的发育产生不良影响，导致出生缺陷儿增多，使出生人口质量下降，增加死亡率。因此 ...
龙燕
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