Results 11 to 20 of about 3,077 (160)

The relationship between serum IL⁃33,vWF,G⁃CSF and prognosis of acute massive hemorrhage patients with transfusion⁃related acute lung injury [PDF]

open access: yes
Objective To explore the predictive value of serum interleukin⁃33(IL⁃33),von Willebrand factor(vWF),and granulocyte colony⁃stimulating factor(G⁃CSF)for the prognosis of acute massive hemorrhage patients withtransfusion⁃related acute lung injury(TRALI ...
DU Dan*,WEI Ge,WANG Lingxue,LIU Hongbin
core   +2 more sources

ICAM-1对脓毒症所致急性肺损伤与呼吸窘迫综合征的临床诊断和预后评估作用

open access: yesZhongguo shiyan zhenduanxue, 2020
目的探讨ICAM-1对脓毒症所致急性肺损伤与呼吸窘迫综合征的临床诊断和预后评估作用。方法选取2018年2月-2019年9月我院收治的脓毒症患者76例,根据其症状表现将其分为单纯脓毒症组43例,合并急性肺损伤组21例,以及同时合并急性肺损伤、呼吸窘迫综合征组12例,分析其ICAM-1水平对于疾病诊断以及预后评估的价值。结果同时合并肺损伤与呼吸窘迫综合征组患者ICAM-1水平以及SOFA评分均高于脓毒症组以及合并肺损伤组 ...
王晓林, 李静, 黄艳丽
doaj  

The effect of glucocorticoids combined with ulinastatin on IL⁃6/IL⁃10 balance and oxygenation index in patients with early acute lung injury after trauma [PDF]

open access: yes
Objective To investigate the clinical efficacy of glucocorticoid combined with ulinastatin in patients with early acute lung injury(ALI)after trauma. Methods A total of 100 patients with early ALI after trauma who admitted to Shengjing Hospital of China ...
LI Tang,WANG Yudong,LI Wenchao
core   +2 more sources

Effects and mechanisms of Pd-Ia on LPS-induced acute lung injury in mice [PDF]

open access: yes, 2016
目的:随着环境的不断恶化,空气质量越来越差,并且已经严重影响到了人们的身体健康,雾霾已经遍布中国的众多城市,使得呼吸系统疾病的发病率日渐升高。急性肺损伤(ALI)/急性呼吸窘迫综合征(ARDS)都是比较常见的临床呼吸系统疾病,ARDS对于临床疾病来说,可谓是灾难性的,属于严重的呼吸衰竭,目前无有效的药物治疗措施。ALI是ARDS的早期阶段,其特点是弥漫性的炎症损伤,目前研究发现中药白花前胡根中提取出的活性成分白花前胡甲素(Pd-Ia)在LPS诱导的内皮细胞炎症损伤中具有良好的抗炎效果 ...
周晓霞
core  

Relationship between Th1/ Th2 cytokines and severity of acute lung injury secondary to sepsis [PDF]

open access: yes
"Objective To analyze the effects of helper T cells(Th)1 and Th2 cytokines on the severity of acute lung injury(ALI)secondary to sepsis and to analyze their roles in evaluating the occurrence of ALI secondary to sepsis.Methods Clinical data of 206 ...
FU Daoliang,CHEN Dejian,REN Lei,HOU Xiaolin
core   +2 more sources

Expressions of IL-1α, IL-1β and IL-13 mRNA in Lung Tissue and Serum of Rats Drown in Fresh Water [PDF]

open access: yes, 2018
Objective To detect the changes of (interleukin, IL) -1α, IL-1β and IL-13 mRNA in lung tissue and serum of drown rats, and to explore the potential value for the diagnosis of drowning in forensic practice.
JIANG Mei-ling, LIU Zhi-jie, PAN Jing,et al
core   +1 more source

急性纤维素性机化性肺炎1例

open access: yesZhongguo shiyan zhenduanxue, 2023
急性纤维素性机化性肺炎(AFOP)是一种罕见的急性/亚急性肺损伤病理类型,属于特发性间质性肺炎的一个特殊类别,主要病理表现为肺泡内纤维蛋白球以及机化的疏松结缔组织[1]。主要临床表现为呼吸困难、咳嗽、咯血、胸痛、发热等,影像学主要表现为肺部弥漫、斑片状分布的实变影。与许多疾病密切相关,并具有相同的临床影像学和病理学特征[2]。AFOP临床诊断较为困难,且容易被误诊为其他多种症状相似的肺部疾病,
刘嘉斌, 张晓华
doaj  

涎液化糖链抗原-6在脓毒症相关性ARDS中的研究进展

open access: yesZhongguo shiyan zhenduanxue, 2023
急性呼吸窘迫综合征(ARDS)是一种急性弥漫性炎症性肺损伤,以肺泡炎症、肺泡-毛细血管屏障破坏为主要特征,典型的临床表现为进行性加重的低氧血症且难以纠正,其影像学可见双肺非均一性的浸润状阴影[1]。ARDS的发病机制尚不明确,但发现各种直接或间接的原因可导致上皮细胞或毛细血管内皮细胞受损,屏障功能的破坏令细胞通透性增加,肺间质和肺泡内逐渐积聚大量液体,形成肺水肿,而肺表面活性物质也会在短时间内被消耗殆尽,诱导肺不张形成,致使肺顺应性下降,最终导致难以纠正的低氧血症,严重时可危及生命[2]。
韩露晴, 王帅, 连德德, 赵忠岩
doaj  

Research progress on the pathogenesis of acute lung injury in sepsis [PDF]

open access: yes
Sepsis is a systemic inflammatory response syndrome caused by severe infection leading to host dysfunction,often involving multiple organs and causing functional failure.
WANG Qin,YU Xu,LI Qingying,LU Yibin
core   +2 more sources

急性肺损伤实验动物模型的特征和评价方法

open access: yesZhongguo shiyan zhenduanxue, 2017
急性肺损伤(ALI)和急性呼吸窘迫综合征(ARDS)是指心源性以外的各种肺内、外致病因素导致的急性、进行性、缺氧性急性呼吸衰竭。急性肺损伤最严重的情况就是急性呼吸窘迫综合征[1]。流行病学调查显示ALI/ARDS是临床常见危重症,其发病机制目前尚不清楚,缺少敏感、特异的指标,使得治疗上的总体预后改善并不大,因此动物模型为研究急性肺损伤提供了较大帮助。目前研究急性肺损伤的动物模型有鼠类、兔、犬、猪、绵羊、山羊及灵长类等动物,但由于动物和人的肺部解剖结构和对抗损伤的防御机制不同 ...
刘泽茹, 宋磊, 李丹
doaj  

Home - About - Disclaimer - Privacy