[Efficacy and safety of venetoclax-cytarabine-homoharringtonine-based cytoreductive therapy before allogeneic hematopoietic stem cell transplantation in refractory/relapsed acute myeloid leukemia with RUNX1::RUNX1T1: a retrospective study]. [PDF]
Zhonghua Xue Ye Xue Za ZhiZhang ZL +7 more
europepmc +1 more source
Zhongshan Daxue xuebao. Yixue kexue ban动脉粥样硬化（AS）是一种缓慢而复杂的疾病，涉及多种因素，包括脂质代谢紊乱、氧自由基产生、炎性细胞浸润以及局部血栓形成等。近年来铜死亡作为一种新发现的、依赖于铜离子的程序性细胞死亡方式而备受关注，其主要因过多的铜离子与硫辛酰化蛋白结合导致三羧酸循环（TCA）紊乱，破坏铁硫簇蛋白，影响相关酶和蛋白的正常功能，多途径引发细胞死亡。以往研究发现，铜死亡与AS的发生发展密切相关，铜死亡可以促进氧自由基产生、通过芬顿反应引发脂质过氧化、诱导炎症反应、干扰线粒体TCA循环等，影响巨噬细胞 ...
张子路, 秦合伟
doaj
[The role and mechanism of chemokine network in promoting osteoarthritis progression by regulating synovial macrophage heterogeneity]. [PDF]
Zhongguo Xiu Fu Chong Jian Wai Ke Za ZhiLin Y, Wu L, Chen Q, Shen B.
europepmc +1 more source
[Allergens induce activation of blood CCR3<sup>+</sup> granulocyte subsets in patients with perennial allergic rhinitis]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoWang Q +5 more
europepmc +1 more source
[CAR-T cell therapy bridging to allogeneic hematopoietic stem cell transplantation for diffuse large B-cell Richter syndrome: a case report and literature review]. [PDF]
Zhonghua Xue Ye Xue Za ZhiWang Y +5 more
europepmc +1 more source
Linchuang shenzangbing zazhi铜稳态在肾脏疾病的发生和发展中具有重要意义。铜死亡已在包括肾细胞癌的肿瘤领域广为研究，但其在急性肾损伤和慢性肾脏病中鲜见报道。铜死亡相关基因脂酰转移酶1显示了对IgA肾病的预测价值；晚期慢性肾脏病患者血铜升高，在动物模型中证实铜螯合剂可以抑制肾脏纤维化。线粒体功能障碍是铜死亡的标志。肾小管细胞富含线粒体易受活性氧簇攻击，且高表达铜转运蛋白，在药物的摄取和转运中发挥重要作用。因此，本文旨在总结铜死亡在肾脏疾病中的研究进展并探寻铜死亡与急性肾损伤的潜在联系，以期为肾脏疾病的治疗提供新思路。
doaj
[Chronic myelomonocytic leukemia complicated with T-lymphoblastic lymphoma: a case report and literature review]. [PDF]
Zhonghua Xue Ye Xue Za ZhiYang YZ, Xu WY, Jiao YJ, Guo ZX.
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Zhongshan Daxue xuebao. Yixue kexue ban, 2008 【目的】 探讨非清髓性异基因造血干细胞移植(Allo*9鄄HSCT)治疗重型再生障碍性贫血(SAA)的近期疗效及其并发症?【方法】 9例确诊的年轻SAA患者接受了同胞HLA全相合外周造血干细胞(PBSC)移植,预处理方案为:环磷酰胺(50 mg· kg-1·d-1,移植前5 d至移植前2 d静滴)+兔抗人胸腺细胞球蛋白(antithymocyte globulin, 2.5 mg·kg-1·d-1,移植前5 d至移植前3 d静滴)?观察移植后临床造血重建时间及近期并发症,并于移植后40 d?180 ...
doaj
[Research progress on the correlation between Akkermansia muciniphila and cardiovascular diseases]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoJiang S, Gong L, Zheng H.
europepmc +1 more source
[Chinese guidelines for diagnosis and treatment of myelodysplastic neoplasms (2026)]. [PDF]
Zhonghua Xue Ye Xue Za ZhiChinese Society of Hematology +1 more
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