Results 1 to 10 of about 36,283 (168)

Decreased in n‐3 DHA enriched triacylglycerol in small extracellular vesicles of diabetic patients with cardiac dysfunction 糖尿病合并心脏功能障碍患者细胞外小囊泡中n‐3 DHA 富集的三酰甘油减少

Journal of Diabetes, Volume 15, Issue 12, Page 1070-1080, December 2023., 2023
Highlights Lipid profiles of small extracellular vesicles (sEVs) in patients with diabetes or diabetic cardiovascular disease are rarely reported. n‐3 docosahexaenoic acid (DHA)‐enriched triacylglycerol (TG) was found to decrease in sEVs from serum of patients with diabetic cardiovascular disease (DM‐CAD).
Wei Ding, Xuejuan Zhang, Dandan Xiao, Wenguang Chang   +3 more
wiley   +1 more source

Fatty acid β‐oxidation and mitochondrial fusion are involved in cardiac microvascular endothelial cell protection induced by glucagon receptor antagonism in diabetic mice 脂肪酸β‐氧化和线粒体融合参与胰高血糖素受体拮抗剂对糖尿病小鼠心脏微血管内皮细胞的保护作用

Journal of Diabetes, Volume 15, Issue 12, Page 1081-1094, December 2023., 2023
Highlights Glucagon receptor (GCGR) monoclonal antibody (mAb) improves cardiac function and attenuates microvascular damage in db/db mice. GCGR mAb ameliorates the oxidative stress of cardiac microvascular endothelial cells in diabetic mice. GCGR mAb counteracts the diabetes‐induced upregulation of carnitine palmitoyltransferase 1B, optic atrophy type ...
Peng Wang, Rui Wei, Xiaona Cui, Zongzhe Jiang, Jin Yang, Lingyun Zu, Tianpei Hong   +6 more
wiley   +1 more source

Sensitivity of a Hymenoptera serological immunoglobulin (Ig)E assay for the diagnosis of venom hypersensitivity in dogs

Veterinary Dermatology, Volume 34, Issue 6, Page 543-553, December 2023., 2023
Background – Hymenoptera envenomation with honey bee (Apis mellifera) and paper wasp (Polistes spp.) may cause life‐threatening anaphylaxis in dogs. In human patients, clinical history, intradermal testing (IDT) and measurement of allergen‐specific serological immunoglobulin (Ig)E (sIgE) are used to support a diagnosis of Hymenoptera venom ...
Hilary H. Chan, Amanda K. Burrows, Giselle Hosgood, Rudayna Ghubash   +3 more
wiley   +1 more source

Exosomal miR‐let‐7c‐5p is involved in the cognitive function of type 2 diabetes mellitus patients by interleukin 10: A cross‐sectional study 外泌体miR‐let‐7c‐5p通过白细胞介素10参与2型糖尿病患者的认知功能:一项横断面研究

Journal of Diabetes, Volume 15, Issue 11, Page 978-986, November 2023., 2023
Highlights Both interleukin‐10 levels and exosomal miR‐let‐7c‐5p levels are correlated with cognitive function in patients with type 2 diabetes mellitus. There is a negative association between interleukin‐10 levels and exosomal miR‐let‐7c‐5p levels in the plasma of patients with type 2 diabetes mellitus. Abstract Background Interleukin (IL)‐10 plays a
Hui Zhang, Shufang Yang, Wenwen Zhu, Tong Niu, Jue Wang, Mingyue Yang, Enlin Liu, Jumei Wang, Sumei Li, Haoqiang Zhang   +9 more
wiley   +1 more source

老年急性白血病患者临床和实验室特征分析

Zhongguo shiyan zhenduanxue, 2023
白血病在全球范围内发病率呈逐年上升趋势[1],据我国国家癌症中心最新统计，我国白血病发病率为6.21/10万，死亡率达4.03/10万，预后极差[2]。我国成年人白血病以急性白血病(AL)为主，年龄越大，预后越差。目前我国人口老龄化程度加剧，老年人口规模庞大，60岁及以上人口达2.67亿人，老年急性白血病患者逐年增多，已成为成人急性白血病群体的核心人群。老年人身体各脏器机能衰退，体能状态差，骨髓造血储备功能减退，且易合并高血压、糖尿病、
赵晶晶, 王晓柔, 王亚南, 宋琛, 戴许阳, 鲁广建, 焦路阳   +6 more
doaj  

VEGF、α-HBDH和β2-微球蛋白在儿童急性白血病诊断及预后中的价值

Zhongguo shiyan zhenduanxue, 2023
白血病是我国儿童发病率最高的恶性肿瘤，达4.3/10万人，且呈逐年上升趋势[1],每年在治的病患人数约4.5万，是儿童第2位的死亡病因，造成了严重的疾病和经济负担。儿童白血病患中90%以上为急性白血病，其中急性淋巴细胞白血病(ALL)占比约2/3。目前儿童急性白血病发病机制和发病原因不详，早期诊断与尽早干预治疗是改善预后和降低死亡率的关键措施。有研究显示，血管内皮生长因子(VEGF)、
赵晶晶, 张敏, 林志强, 张华丽, 鲁广健   +4 more
doaj  

Predictive performance of Fetal Medicine Foundation first‐trimester screening algorithm for pre‐eclampsia according to conception mode

Ultrasound in Obstetrics &Gynecology, Volume 67, Issue 6, Page 806-814, June 2026.
ABSTRACT Objective To investigate the incidence of pre‐eclampsia (PE) and the predictive performance of the Fetal Medicine Foundation (FMF) first‐trimester PE screening algorithm across pregnancies conceived using assisted reproductive technology (ART), after ovulation induction (OI) and through spontaneous conception (SC).
A. S. L. Kjaer, I. Riishede, L. Rode, R. B. Jensen, K. Pihl, L. Sperling, M. Overgaard, N. G. Pedersen, A. C. Roslev, P. Sandager, A. Tabor, A. Pinborg, C. K. Ekelund, the PRESIDE Study Group, P. Nørgaard, C. Vedel, H. Skov, S. R. Wagner, H. J. Zingenberg, M. R. Andersen, L. Bathum, T. Hilling, C. S. Knudsen, F. S. Jørgensen   +23 more
wiley   +1 more source

Predictive value of gB2 antibodies for maternal–fetal transmission after primary cytomegalovirus infection treated with valacyclovir

Ultrasound in Obstetrics &Gynecology, Volume 67, Issue 4, Page 455-460, April 2026.
ABSTRACT Objective To estimate the residual risk of maternal–fetal transmission after primary cytomegalovirus (CMV) infection in the periconceptional period or the first trimester in women treated with valacyclovir, and to assess whether the presence of glycoprotein B2 (gB2)‐specific immunoglobulin (Ig)‐G antibodies on immunoblot analysis refines fetal
K. O. Kagan, A. L. Bissinger, O. Roth, J. Sonek, M. Hoopmann, Y. Ville, M. Enders   +6 more
wiley   +1 more source

Roles of TIF1β in Leukemic Stem Cell Through SETDB1‐Dependent and Independent Mechanisms

Cancer Science, Volume 117, Issue 4, Page 896-903, April 2026.
In leukemic stem cell, BCR::ABL cooperates with TIF1β to open chromatin at oncogenes and close chromatin at differentiation regulators, driving leukemic reprogramming. In TIF1β‐deficient stem cell, the loss of TIF1β inverts this balance, showing closed chromatin at oncogenes and open chromatin at differentiation regulators.
Mariko Morii, Sho Kubota, Goro Sashida
wiley   +1 more source

World Association for Veterinary Dermatology Consensus Statement for Diagnosis, and Evidence‐Based Clinical Practice Guidelines for Treatment and Prevention of Canine Leishmaniosis

Veterinary Dermatology, Volume 36, Issue 6, Page 723-787, December 2025.
Hyperkeratosis of (a) the footpads and (b) the nasal planum. ABSTRACT Background Canine leishmaniosis (CanL) due to Leishmania infantum remains common, and veterinarians do not always follow scientifically sound approaches for diagnosis, treatment and prevention. Objectives To provide consensus guidelines for diagnosis and evidence‐based guidelines for
Manolis N. Saridomichelakis, Gad Baneth, Silvia Colombo, Filipe Dantas‐Torres, Lluís Ferrer, Alessandra Fondati, Guadalupe Miró, Laura Ordeix, Domenico Otranto, Chiara Noli   +9 more
wiley   +1 more source