Results 21 to 30 of about 29,747 (166)
Ultrasound in Obstetrics &Gynecology, Volume 66, Issue 2, Page 200-209, August 2025.Abstract Objectives Neonates with critical congenital heart disease (CCHD) are at risk for adverse early brain development and long‐term neurodevelopmental sequelae. Insulin‐like growth factor‐1 (IGF‐1) and insulin‐like growth factor binding protein‐3 (IGFBP‐3) are essential contributors to brain growth and maturation.
M. Nijman +33 more
wiley +1 more source
Ultrasound in Obstetrics &Gynecology, Volume 65, Issue 4, Page 447-455, April 2025.ABSTRACT Objective A soluble fms‐like tyrosine kinase‐1 (sFlt‐1)‐to‐placental growth factor (PlGF) ratio cut‐off of 38 is currently considered optimal for ruling out pre‐eclampsia (PE); however, implementation of this ratio in clinical practice is limited.
M. N. Nan +15 more
wiley +1 more source
伴有髓系抗原标记的儿童急性B淋巴细胞白血病患者血液形态学、流式免疫表型特点研究
Zhongguo shiyan zhenduanxue, 2021 急性B淋巴细胞白血病是临床上高发的儿童恶性肿瘤疾病,一般占儿童恶性肿瘤疾病发病率的20%以上,发病率近年来呈逐年增加的趋势[1-2]。急性B淋巴细胞白血病是急性白血病最常见的类型,但是由于该疾病涉及数十种特异染色体异位形成一种融合基因,而多种融合基因也导致了急性B淋巴细胞白血病发病机制的复杂性,从而给临床医师治疗形成了巨大的困难[3-4]。本次研究分析伴有髓系抗原标记的儿童急性B淋巴细胞白血病患者血液形态学、流式免疫表型特点,为临床医师治疗急性B淋巴细胞白血病患儿提供理论依据,现报道如下。
焦聿墨, 马林通, 王鼎, 赵鹏
doaj
Analysis of Hes1 mediated development and maintenance of leukemic stem cells for myeloid leukemia [PDF]
, 2013 科学研究費助成事業(学術研究助成基金助成金)研究成果報告書：若手研究(B)2011-2012 課題番号：23791068research ...
坂田（柳元） 麻実子
core
記憶型T幹細胞を頂点とした成人T細胞白血病の階層構造の解明 [PDF]
, 2015 京都大学0048新制・課程博士博士(医学)甲第19267号医博第4031号新制||医||1011(附属図書館)32269京都大学大学院医学研究科医学専攻(主査)教授 小川 誠司, 教授 生田 宏一, 教授 松岡 雅雄学位規則第4条第1項該当Doctor of Medical ScienceKyoto ...
Nagai, Yuya
core +1 more source
Zhongshan Daxue xuebao. Yixue kexue ban, 2002 【目的】探讨细胞间黏附分子-1(CD54)在恶性血液病的表达。【方法】用免疫荧光方法检测19 例急性髓系白血 病, 34 例急性淋巴细胞白血病, 10 例慢性粒细胞白血病, 15 例多发性骨髓瘤, 21 例非霍奇金淋巴瘤和16 例正常人骨髓单个核 细胞表达CD54 。【结果】①除多发性骨髓瘤、慢性粒细胞性白血病外, 急性髓性白血病细胞、非霍奇金淋巴瘤、急性淋巴细胞 白血病患者骨髓单个核细胞表面CD54表达低于正常人。②CD54在急性早幼粒细胞白血病(M3)表达高于在其它类型急性髓 ...
童秀珍 +5 more
doaj
Veterinary Dermatology, Volume 35, Issue 6, Page 595-604, December 2024.Background – Mycobacterium cell wall fraction (MCWF) is derived from nonpathogenic Mycobacterium phlei and is used as an immunomodulatory compound in clinical practice, yet its mode‐of‐action requires further research. Objective – To evaluate the host response to MCWF in canine peripheral blood mononuclear cells (PBMCs) by using enzyme‐linked ...
Robert Ward +9 more
wiley +1 more source
Huli yanjiu, 1988 科护士长 今天讨论1例急性粒细胞性白血病病人的护理。我先介绍一下白血病的病因: 白血病的发病目前认为与病毒感染有关,在实验中发现一种C型核糖核酸肿瘤病毒能使动物产生白血病或淋巴瘤,认为C型肿瘤病毒可能就是白血病发生的原因。 白血病的发生还受物理因素影响。电离辐射可诱发。（1）辐射可引起细胞染色体畸变 ...
陈喜莲, 郑秀萍
doaj
Involvement of Abnormal MicroRNA Expression in the Mechanism of Drug Resistance with Acute Myeloid Leukemia [PDF]
, 2016 目的：分析miRNA-98的表达异常在急性髓系白血病化疗耐药机制的作用，通过靶向过表达miRNA-98的表达水平探讨以miRNA-98为靶点增加化疗药物敏感性的可能性并分析其可能作用的机制。评价异常表达的血清miRNA-155是否可作为急性髓系白血病的预后标志。 方法：离体实验中，采用qRT-PCR方法检测K562和其耐药株K562/A02中miR-98、E2F1基因表达情况。通过瞬时转染miR-98mimic处理耐药细胞K562/A0248h后，通过qRT-PCR法检测miR-98表达情况；通过qRT-
黄英丹
core
Ultrasound in Obstetrics &Gynecology, Volume 64, Issue 4, Page 470-479, October 2024.ABSTRACT Objectives Our aim was to examine the prenatal profiles of pregnancies affected by an atypical chromosomal aberration, focusing on pathogenic copy‐number variants (pCNVs). We also wanted to quantify the performance of combined first‐trimester screening (cFTS) and a second‐trimester anomaly scan in detecting these aberrations. Finally, we aimed
K. Gadsbøll +6 more
wiley +1 more source