Results 21 to 30 of about 20,063 (118)

Cord blood levels of insulin‐like growth factor‐1 and insulin‐like growth factor binding protein‐3 correlate with perinatal brain development in fetal congenital heart disease

Ultrasound in Obstetrics &Gynecology, Volume 66, Issue 2, Page 200-209, August 2025.
Abstract Objectives Neonates with critical congenital heart disease (CCHD) are at risk for adverse early brain development and long‐term neurodevelopmental sequelae. Insulin‐like growth factor‐1 (IGF‐1) and insulin‐like growth factor binding protein‐3 (IGFBP‐3) are essential contributors to brain growth and maturation.
M. Nijman, N. H. P. Claessens, J. M. P. J. Breur, L. Reijn, N. J. G. Jansen, I. M. van Ooijen, R. de Heus, C. H. Nijboer, M. N. Bekker, M. J. N. L. Benders, R. Stegeman, J. E. G. Vaes, the CHD LifeSpan Study Group Utrecht, Joppe Nijman, Thomas Alderliesten, Rian Bosch, Roelie M. Wösten‐van Asperen, Henriette ter Heide, Trinette J. Steenhuis, Martijn G. Slieker, Gabrielle G. van Iperen, Kim van Loon, Boyd V. Martherus, Erik Koomen, Abraham van Wijk, Paul H. Schoof, Hanna Talacua, Neeltje Crombag, Bauke M. Adriaanse, Niels Blanken, Rutger A.J. Nievelstein, Monique M.J. van Schooneveld, Lotte Soeters, Maaike C.A. Sprong   +33 more
wiley   +1 more source

N‐terminal pro B‐type natriuretic peptide as biomarker to predict pre‐eclampsia and maternal–fetal complications

Ultrasound in Obstetrics &Gynecology, Volume 65, Issue 4, Page 447-455, April 2025.
ABSTRACT Objective A soluble fms‐like tyrosine kinase‐1 (sFlt‐1)‐to‐placental growth factor (PlGF) ratio cut‐off of 38 is currently considered optimal for ruling out pre‐eclampsia (PE); however, implementation of this ratio in clinical practice is limited.
M. N. Nan, C. Garrido‐Giménez, Á. Garcia‐Osuna, P. Garcia Manau, J. Ullmo, J. Mora, O. Sanchez‐Garcia, J. Platero, M. Cruz‐Lemini, E. Llurba, on behalf of the EuroPE working group, M. Vila‐Cortés, M. J. Pelegay, M. Ricart, B. Muñoz‐Abellana, X. Gabaldó Barrios   +15 more
wiley   +1 more source

Analysis of the immunomodulatory properties of mycobacterium cell wall fraction on the cytokine production of peripheral blood mononuclear cells of healthy dogs

Veterinary Dermatology, Volume 35, Issue 6, Page 595-604, December 2024.
Background – Mycobacterium cell wall fraction (MCWF) is derived from nonpathogenic Mycobacterium phlei and is used as an immunomodulatory compound in clinical practice, yet its mode‐of‐action requires further research. Objective – To evaluate the host response to MCWF in canine peripheral blood mononuclear cells (PBMCs) by using enzyme‐linked ...
Robert Ward, Geoffrey A. Wood, Charlotte Pye, Khalil Karimi, Anthony Yu, Myles St‐Denis, Katherine Blake, Sugandha Raj, Samson Oladokun, Shayan Sharif   +9 more
wiley   +1 more source

Combined first‐trimester screening and invasive diagnostics for atypical chromosomal aberrations: Danish nationwide study of prenatal profiles and detection compared with NIPT

Ultrasound in Obstetrics &Gynecology, Volume 64, Issue 4, Page 470-479, October 2024.
ABSTRACT Objectives Our aim was to examine the prenatal profiles of pregnancies affected by an atypical chromosomal aberration, focusing on pathogenic copy‐number variants (pCNVs). We also wanted to quantify the performance of combined first‐trimester screening (cFTS) and a second‐trimester anomaly scan in detecting these aberrations. Finally, we aimed
K. Gadsbøll, I. Vogel, S. E. Kristensen, L. H. Pedersen, J. Hyett, O. B. Petersen, The Danish Cytogenetic Central Register study group   +6 more
wiley   +1 more source

白血病基因诊断及其信息系统建立

Zhongguo shiyan zhenduanxue, 2006
目的用基因诊断技术对白血病分型诊断及微小残留病（MRD）监控,同时对所检测数据建立信息系统。方法巢式RT-PCR扩增急髓性白血病融合基因,PCR扩增急性淋巴细胞白血病基因重排,用Delphi程序设计信息系统。结果M2b型白血病能扩增出AML1/ETO融合基因;M3型白血病能检测出L型和S型融合基因;慢粒白血病可检测出b3a2和b2a3融合基因;急淋白血病可检测出IgH、TCRγ、TCRδ基因重排。结论基因诊断能有效进行白血病分型及MRD监控,信息系统的建立方便了检测信息的管理及查询。
孙新六
doaj  

Maternal antenatal depression, oxytocin, and infant temperament: The roles of ethnicity and adult attachment avoidance

Infant Mental Health Journal: Infancy and Early Childhood, Volume 45, Issue 5, Page 516-528, September 2024.
Abstract This study examined the associations between maternal depression and oxytocin in pregnancy, caregiving sensitivity and adult attachment style, and infant temperament. One hundred and six women recruited from a public hospital antenatal clinic in Australia, and their infants completed assessments at three time points (Time 1: pregnancy; Time 2:
Jane Kohlhoff, Lisa Karlov, Mark Dadds, Bryanne Barnett, Derrick Silove, Valsamma Eapen   +5 more
wiley   +1 more source

探讨白血病患者骨髓中VEGF、bFGF、sICAM-1及CD105的表达对髓血屏障调节机制的影响

Zhongguo shiyan zhenduanxue, 2012
目的探讨白血病患者骨髓中VEGF、bFGF、sICAM-1及CD105的表达对髓血屏障调节机制的影响。方法采用原位杂交方法,用CD105标记骨髓活化的血管内皮细胞;用ELISA方法检测骨髓液VEGF、bFGF、sICAM-1的表达水平。结果 CD105在白血病的表达以急性髓系白血病（AML-M5）最高,急性髓系白血病（AML）AML-M3表达最低。AML-M5的阳性表达率为（52.32±15.34）%,明显高于正常对照组[（2.32±0.87）%]（P0.05 ...
马传香, 高昆山, 刘树刚, 李骞, 王树庆   +4 more
doaj  

Maternal ethnicity and socioeconomic deprivation: influence on adverse pregnancy outcomes

Ultrasound in Obstetrics &Gynecology, Volume 64, Issue 2, Page 187-192, August 2024.
ABSTRACT Objective To evaluate the relative importance of ethnicity and socioeconomic deprivation in determining the likelihood and prevalence of placentally derived composite of adverse pregnancy outcomes (CAPO) and composite of severe adverse pregnancy outcomes (CAPO‐S).
M. Minopoli, L. Noël, A. Dagge, G. Blayney, A. Bhide, B. Thilaganathan   +5 more
wiley   +1 more source

Rituximab with standard LMB chemotherapy in pediatric high‐risk mature B‐cell non‐Hodgkin lymphoma: A report from the JPLSG B‐NHL14 trial

European Journal of Haematology, Volume 112, Issue 4, Page 585-593, April 2024.
Abstract Background The benefit of adding rituximab to standard lymphomes malins B (LMB) chemotherapy for children with high‐risk mature B‐cell non‐Hodgkin lymphoma (B‐NHL) has previously been demonstrated in an international randomized phase III trial, to which the Japanese Pediatric Leukemia/Lymphoma Study Group could not participate.
Tetsuya Mori, Tomoo Osumi, Akiko Kada, Kentaro Ohki, Yuhki Koga, Reiji Fukano, Naoto Fujita, Tetsuo Mitsui, Takeshi Mori, Akiko M. Saito, Atsuko Nakazawa, Ryoji Kobayashi, Masahiro Sekimizu   +12 more
wiley   +1 more source

血糖波动与早期糖尿病肾病微量白蛋白尿的关系

Zhongguo shiyan zhenduanxue, 2010
目的探讨血糖波动与早期糖尿病肾病微量白蛋白尿之间的关系。方法对40例尿白蛋白排泄率（UAER）≤20μg/min（正常白蛋白尿组）及40例UAER 20-199μg/min（微量白蛋白尿组）的2型糖尿病患者进行动态血糖监测（CGMS）,然后比较两组患者的平均血糖、平均血糖波动振幅（MAGE）及血糖标准差（SDBG）。结果两组患者的平均血糖水平（11.07±1.94 mmol/L vs 10.45±1.90 mmol/L）无统计学差异;微量白蛋白尿组,血糖标准差（3.14±0.94 mmol/L vs 2.
何扬芳, 姚宪章, 葛焕琦, 潘焕峰   +3 more
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