Results 11 to 20 of about 29,747 (166)

Decreased in n‐3 DHA enriched triacylglycerol in small extracellular vesicles of diabetic patients with cardiac dysfunction 糖尿病合并心脏功能障碍患者细胞外小囊泡中n‐3 DHA 富集的三酰甘油减少

Journal of Diabetes, Volume 15, Issue 12, Page 1070-1080, December 2023., 2023
Highlights Lipid profiles of small extracellular vesicles (sEVs) in patients with diabetes or diabetic cardiovascular disease are rarely reported. n‐3 docosahexaenoic acid (DHA)‐enriched triacylglycerol (TG) was found to decrease in sEVs from serum of patients with diabetic cardiovascular disease (DM‐CAD).
Wei Ding, Xuejuan Zhang, Dandan Xiao, Wenguang Chang   +3 more
wiley   +1 more source

Fatty acid β‐oxidation and mitochondrial fusion are involved in cardiac microvascular endothelial cell protection induced by glucagon receptor antagonism in diabetic mice 脂肪酸β‐氧化和线粒体融合参与胰高血糖素受体拮抗剂对糖尿病小鼠心脏微血管内皮细胞的保护作用

Journal of Diabetes, Volume 15, Issue 12, Page 1081-1094, December 2023., 2023
Highlights Glucagon receptor (GCGR) monoclonal antibody (mAb) improves cardiac function and attenuates microvascular damage in db/db mice. GCGR mAb ameliorates the oxidative stress of cardiac microvascular endothelial cells in diabetic mice. GCGR mAb counteracts the diabetes‐induced upregulation of carnitine palmitoyltransferase 1B, optic atrophy type ...
Peng Wang, Rui Wei, Xiaona Cui, Zongzhe Jiang, Jin Yang, Lingyun Zu, Tianpei Hong   +6 more
wiley   +1 more source

Sensitivity of a Hymenoptera serological immunoglobulin (Ig)E assay for the diagnosis of venom hypersensitivity in dogs

Veterinary Dermatology, Volume 34, Issue 6, Page 543-553, December 2023., 2023
Background – Hymenoptera envenomation with honey bee (Apis mellifera) and paper wasp (Polistes spp.) may cause life‐threatening anaphylaxis in dogs. In human patients, clinical history, intradermal testing (IDT) and measurement of allergen‐specific serological immunoglobulin (Ig)E (sIgE) are used to support a diagnosis of Hymenoptera venom ...
Hilary H. Chan, Amanda K. Burrows, Giselle Hosgood, Rudayna Ghubash   +3 more
wiley   +1 more source

Exosomal miR‐let‐7c‐5p is involved in the cognitive function of type 2 diabetes mellitus patients by interleukin 10: A cross‐sectional study 外泌体miR‐let‐7c‐5p通过白细胞介素10参与2型糖尿病患者的认知功能:一项横断面研究

Journal of Diabetes, Volume 15, Issue 11, Page 978-986, November 2023., 2023
Highlights Both interleukin‐10 levels and exosomal miR‐let‐7c‐5p levels are correlated with cognitive function in patients with type 2 diabetes mellitus. There is a negative association between interleukin‐10 levels and exosomal miR‐let‐7c‐5p levels in the plasma of patients with type 2 diabetes mellitus. Abstract Background Interleukin (IL)‐10 plays a
Hui Zhang, Shufang Yang, Wenwen Zhu, Tong Niu, Jue Wang, Mingyue Yang, Enlin Liu, Jumei Wang, Sumei Li, Haoqiang Zhang   +9 more
wiley   +1 more source

Successful surgical removal of a pheochromocytoma in a mare via trans‐costal approach

Equine Veterinary Journal, Volume 55, Issue 6, Page 1012-1020, November 2023., 2023
Abstract Background Pheochromocytomas have been previously reported in horses, but successful antemortem diagnosis and surgical removal without recurrence of clinical signs have not been described. Objective To report the clinical presentation, diagnostic evaluation, surgical technique, anaesthetic management and post‐operative care of a mare diagnosed
Thomas J. O'Brien, Lynn M. Pezzanite, Elizabeth V. Acutt, Allison C. Vilander, Diana M. Hassel, Rachel C. Hector, Dean A. Hendrickson   +6 more
wiley   +1 more source

Glycosylated fibronectin improves first‐trimester prediction of pre‐eclampsia

Ultrasound in Obstetrics &Gynecology, Volume 62, Issue 4, Page 512-521, October 2023., 2023
ABSTRACT Objective To determine whether maternal serum glycosylated fibronectin (GlyFn) level in the first trimester increases the sensitivity of the Fetal Medicine Foundation (FMF) triple test, which incorporates mean arterial pressure, uterine artery pulsatility index and placental growth factor, when screening for pre‐eclampsia (PE) in an Asian ...
S. Moungmaithong, X. Wang, C. S. L. Lau, A. W. T. Tse, N. M. W. Lee, H. H. Y. Leung, L. C. Poon, D. S. Sahota   +7 more
wiley   +1 more source

Roles of TIF1β in Leukemic Stem Cell Through SETDB1‐Dependent and Independent Mechanisms

Cancer Science, Volume 117, Issue 4, Page 896-903, April 2026.
In leukemic stem cell, BCR::ABL cooperates with TIF1β to open chromatin at oncogenes and close chromatin at differentiation regulators, driving leukemic reprogramming. In TIF1β‐deficient stem cell, the loss of TIF1β inverts this balance, showing closed chromatin at oncogenes and open chromatin at differentiation regulators.
Mariko Morii, Sho Kubota, Goro Sashida
wiley   +1 more source

World Association for Veterinary Dermatology Consensus Statement for Diagnosis, and Evidence‐Based Clinical Practice Guidelines for Treatment and Prevention of Canine Leishmaniosis

Veterinary Dermatology, Volume 36, Issue 6, Page 723-787, December 2025.
Hyperkeratosis of (a) the footpads and (b) the nasal planum. ABSTRACT Background Canine leishmaniosis (CanL) due to Leishmania infantum remains common, and veterinarians do not always follow scientifically sound approaches for diagnosis, treatment and prevention. Objectives To provide consensus guidelines for diagnosis and evidence‐based guidelines for
Manolis N. Saridomichelakis, Gad Baneth, Silvia Colombo, Filipe Dantas‐Torres, Lluís Ferrer, Alessandra Fondati, Guadalupe Miró, Laura Ordeix, Domenico Otranto, Chiara Noli   +9 more
wiley   +1 more source

Dermoscopic evaluation of normal canine skin with a handheld dermoscope

Veterinary Dermatology, Volume 36, Issue 5, Page 593-601, October 2025.
Background – Dermoscopy is a noninvasive diagnostic tool that provides a magnified view of skin structures. While dermoscopy is described for certain canine dermatological diseases, large‐scale studies evaluating normal skin are lacking. Hypothesis/Objective – This study aimed to correlate dermoscopic findings with histopathological results in healthy ...
Rachael Loek, David Gardiner, George Moore, Ashfaq Marghoob, Carine Laporte   +4 more
wiley   +1 more source

Clinical Features and T‐Cell Repertoire of Chronic Myeloid Leukemia Patients Who Attempt Discontinuation of Tyrosine Kinase Inhibitors: The ISAC‐TFR Study

Cancer Medicine, Volume 14, Issue 15, August 2025.
ABSTRACT Background While tyrosine kinase inhibitor (TKI) discontinuation is an established therapeutic goal, up to 60% of patients relapse after the first attempt. The feasibility of a second or third attempt at TKI discontinuation remains uncertain.
Hiroshi Ureshino, Yukio Nakamura, Yemima Budirahardja, Iwao Nozawa, Keisuke Kidoguchi, Kazuharu Kamachi, Shinya Kimura   +6 more
wiley   +1 more source