Results 41 to 50 of about 1,789 (148)

Study of the relationship between inflammatory reaction and readmission of hospitalized patients with chronic obstructive pulmonary disease complicated with respiratory failure [PDF]

open access: yes
Objective To analyze the relationship between inflammatory reaction and the short-term readmission of hospitalized patients with chronic obstructive pulmonary disease (COPD) complicated with respiratory failure.
ZHENG Yulin, JIN Xuewen, CHEN Kunlun, YAN Lihua
core   +1 more source

The Research Value of Biphasic Registration Quantitative Computed Tomography Emphysema Index in the Evaluation of Mild to Moderate COPD [PDF]

open access: yes
Objective: To find the optimal quantitative index of emphysema by comparing and analyzing the quantitative indexes of emphysema in patients with mild to moderate chronic obstruction pulmonary disease (COPD) via registered biphasic quantitative computed ...
Jianlong LI   +7 more
core   +1 more source

慢性阻塞性肺疾病急性加重期血清CRP与动脉血气联合检测的临床意义

open access: yesZhongguo shiyan zhenduanxue, 2010
目的探讨慢性阻塞性肺疾病急性加重期血清CRP与动脉血气联合检测的临床意义。方法选取2008年12月-2010年1月于我院进行治疗的30例慢性阻塞性肺疾病患者为观察组,选取同期的30名健康人员为对照组,后将观察组急性加重期及缓解期和对照组的血清CRP与动脉血气进行检测及比较。结果经研究比较发现,观察组的急性加重期及缓解期血清CRP明显高于对照组,PaCO2高于对照组,PaO2低于对照组,Sa O2低于对照组,HCO3-水平高于对照组 ...
陈大宇
doaj  

慢性阻塞性肺疾病患者血清中E-选择素含量变化

open access: yesZhongguo shiyan zhenduanxue, 2001
目的 探讨E-选择素在慢性阻塞性肺疾病(COPD)中的作用和临床意义。方法 采用酶联免疫吸附试验(ELISA)的方法检测30例慢性阻塞性肺疾病患者和20例正常对照者血清中的E-选择素的含量并将其与患者动脉血气中PO2、PCO2的关系进行比较。结果30例慢性阻塞性肺疾病患者血清中E-选择素的含量明显高于正常对照组(P<0.01),且急性加重期明显高于缓解期(P<0.001),对19例急性加重期患者治疗前后对比分析具有显著差异(P均<0.001)。同时急性加重期患者E-选择素与PCO2呈正相关 ...
赵景明   +3 more
doaj  

[Associations between airflow obstruction and total and cause-specific mortality in adults in China]. [PDF]

open access: yes, 2017
Objective To examine the prospective associations between airflow obstruction (AFO) and total and cause-specific mortality. Methods The study is based on China Kadoorie Biobank, in which 199 099 men and 287 895 women aged 30 to 79 years at baseline were ...
Bian, Z   +12 more
core   +2 more sources

慢性阻塞性肺疾病评估测试问卷的研究进展

open access: yesZhongguo shiyan zhenduanxue, 2018
慢性阻塞性肺疾病(Chronic obstructive pulmonary disease,COPD)在全球范围内的发病率(约为7%-12%)和死亡率(占全球死亡人数的6%)较高[1,2]。目前,COPD的临床诊断率较低[3,4],在西安对770名志愿者调查显示,18.7%(n=144)的参与者满足COPD的诊断标准,但是只有44名有COPD诊断[5]。研究证实,肺功能检查和问卷相结合可以提高对COPD的诊断率[6 ...
靳蓉晖, 张敏, 王丽
doaj  

黄精多糖通过调控结肠内胆汁酸代谢改善慢性阻塞性肺疾病模型小鼠的结肠损伤 [PDF]

open access: yes
目的探究黄精中性多糖(PSP-NP)对慢性阻塞性肺疾病(COPD)模型小鼠结肠损伤影响及作用机制。方法将雄性C57BL/6J小鼠随机分为空白组,COPD模型组和PSP-NP组,并采用熏烟联合脂多糖(LPS)滴鼻的方式建立COPD模型。PSP-NP组造模同时每日灌胃200 mg/kg的PSP-NP,其余组灌喂同体积的生理盐水。通过苏木精-伊红染色(H&E)染色观察结肠病理学变化,酶联免疫吸附法(ELISA)检测血清中LPS水平、结肠组织中ZO-1、Occludin、白介素-6(IL-6 ...
何丹   +7 more
core   +1 more source

COPD患者急性发作期血清TNF-α和IL-8水平检测及临床意义

open access: yesZhongguo shiyan zhenduanxue, 2011
慢性阻塞性肺疾病(chronic obstructive pulmonarydisease,COPD)是一种慢性气道炎症疾病,患者气流受限不完全可逆,呈进行性发展,近年来其发病率、病死率呈上升趋势,世界银行/世界卫生组织公布,至2020年COPD将位居世界疾病经济负担的第5位,其发病机制复杂 ...
叶先智
doaj  

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