[Application and research progress of metal-organic framework materials in skin repair]. [PDF]
Sheng Wu Yi Xue Gong Cheng Xue Za ZhiMa S, Wu W, Liu H, Liu M, Xing F.
europepmc +1 more source
慢病毒介导shRNA静默CXCR4对Eca109细胞转移特性的影响
Zhongshan Daxue xuebao. Yixue kexue ban, 2010 【目的】 新近研究显示CXCL12/CXCR4通路在食管癌组织中有较高的表达,本研究探讨应用慢病毒介导的RNA干扰技术,有效静默食管癌细胞株Eca109细胞CXCR4的表达,研究CXCL12/CXCR4通路对食管癌Eca109细胞转移能力的影响65377;【方法】 以人CXCR4 mRNA编码序列作为干扰靶点,构建靶向CXCR4的vshRNA表达质粒,另构建不针对任何已知mRNA的阴性对照vshRNA表达质粒,转染相应组别细胞65377;研究分为控制组65380;阴性对照组及静默组65377 ...
doaj
[Application and advances of exosome-hydrogel system in wound healing]. [PDF]
Zhongguo Xiu Fu Chong Jian Wai Ke Za ZhiQiu Y, Tan Q.
europepmc +1 more source
[Comparison of antiviral efficacy of nucleos(t)ide analogue monotherapy and its combination with interferon-α in children 1-6 years-old with HBeAg-positive chronic hepatitis B]. [PDF]
Zhonghua Gan Zang Bing Za ZhiWang ZW +11 more
europepmc +1 more source
[Clinical research advances for small-molecule nucleic acid drugs in the treatment of chronic hepatitis B]. [PDF]
Zhonghua Gan Zang Bing Za ZhiWang WX +4 more
europepmc +1 more source
[Knockdown of <i>Cav1</i> inhibits mitochondrial function and mRNA m<sup>6</sup>A modification and expression of key genes in mouse hepatocytes]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoDing S +4 more
europepmc +1 more source
[High expression of MPP6 predicts poor patient prognosis and promotes malignant biological behaviors of hepatocellular carcinoma cells]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoYu H +5 more
europepmc +1 more source
[Research Advances on Natural Products in Maintaining Oral Microecological Balance]. [PDF]
Sichuan Da Xue Xue Bao Yi Xue BanLiu Y, Ma Q, Meng M, Wu Y, Zou J.
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Zhongshan Daxue xuebao. Yixue kexue ban, 2011 【目的】 探讨超顺磁性氧化铁(SPIO)活体动态示踪小型猪骨髓间充质干细胞(MSC)移植治疗心肌梗死的可行性。【方法】 采用密度梯度离心法获取小型猪自体骨髓MSC,用携带绿色荧光蛋白(GFP)基因的慢病毒载体转染MSC,并用SPIO体外标记MSC-GFP。采用经皮球囊封堵法制备急性心肌梗死(AMI)模型,双标记的MSC经冠脉移植入小型猪心肌梗死区域，移植后24 h、3周、8周在MRI下进行活体动态示踪。【结果】 普鲁士蓝染色显示25 µg Fe/mL SPIO与0.8 µL ...
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外源性SHIP基因表达抑制生长因子介导的 K562细胞增殖及Akt磷酸化
Zhongshan Daxue xuebao. Yixue kexue ban, 2009 【目的】 探讨SHIP基因对IL-3诱导K562细胞系增殖的抑制作用,阐明SHIP对K562细胞作用的机制65377;【方法】 将慢病毒质粒pReceiver-Lv31-FIV和pReceiver-Lv31-SHIP转染K562细胞;转染细胞与IL-3共培养,Western blot法检测K562细胞Akt磷酸化;观察转染野生型SHIP基因对K562细胞增殖的影响;末端脱氧核苷酸转移酶介导的dUTP缺失末端标记(TUNEL)法检测细胞凋亡65377;【结果】 重组慢病毒载体pReceiver-Lv31 ...
doaj