Results 51 to 60 of about 16,260 (175)
The Microstructure Evolution and Mechanical Properties of (FeCoCrNi)100‐x(AlCu)x High‐Entropy Alloys
ABSTRACT This study systematically investigates the effects of AlCu addition on the microstructural evolution and mechanical properties of (FeCoCrNi)100‐x(AlCu)x (x = 0, 5, 10, 15, 20; at%) high‐entropy alloys (HEAs). The results reveal that the microstructure evolves from coarse equiaxed to refined equiaxed, dendritic, and ultimately dual‐phase ...
Shunfu Xie +7 more
wiley +1 more source
Subsidies, Net Zero Transition and Public Debt: An Analysis for the Oil and Gas Industry in Brazil
Abstract Despite awareness of the challenges in promoting the decarbonization of the economy, explicit fossil fuel subsidies have increased considerably worldwide in the past decade, reaching an all‐time high at US$1 trillion in 2022. Considering the net‐zero transition and the increase of modern public debt, this article assesses the most relevant ...
Fernando Inti Leal +2 more
wiley +1 more source
Construction and preliminary application of human naïve phage antibody library [PDF]
治疗性抗体在临床的应用已从30年代的抗血清时代经由80年代后的单克隆抗体时代进入到今天的基因工程抗体时代。目前处于各期临床的生物新药中,基因工程抗体是最多的一类,显示出治疗性抗体具有广阔的临床应用前景,而人源抗体是治疗性抗体的发展趋势。人源性噬菌体抗体库技术解决了人源性单抗来源困难、人体杂交瘤系统低效及鼠单抗的动物源性难题,是分子生物学和免疫学领域中一个强有力的研究手段。本研究从20例未经免疫的健康人的外周血中分离出淋巴细胞,提取总RNA并纯化出mRNA,然后反转录成cDNA ...
李利峰
core
ABSTRACT “Opération Papyrus” was implemented in the Swiss Canton of Geneva between 2017 and 2018 with the aim of granting residence permits to undocumented migrants who met pre‐established criteria. This program serves as an exemplary case of involving nongovernmental actors to facilitate what were originally state‐controlled procedures.
Jan‐Erik Refle +3 more
wiley +1 more source
"fordi før så skreiv æ Å-G". En studie om andreklassingers valg av stavemåter.
The purpose of this master's thesis has been to look at the choices students in Year 2 make when spelling words. The students participating in this research are in the transition between phonological and orthographic writing, and the study will focus on how these students adopt different spelling strategies. The assignment's data material is taken from
openaire +1 more source
Induced Pluripotent Stem Cell-derived Mesenchymal Stem Cells Improve Crohn’s Disease via Altered T Cell Differentiation [PDF]
背景&目的:目前,有许多研究表明,无论是脂肪来源还是骨髓来源的的间充质干细胞都对克罗恩病和溃疡性结肠病实验室模型有益。甚至有些临床的一期实验,已经证明了间充质干细胞可以缓解炎症性肠病的临床症状和组织病理学损伤。然而,限制间充质干细胞临床研究与应用的最主要原因就是间充质干细胞在组织中的含量有限,很难得到充足的干细胞,满足临床研究和应用的需求,并且提取细胞的过程也会给病人或者细胞捐献者带来极大的痛苦。在此,我们的研究目的主要是探讨另一种新型来源的间充质干细胞即诱导多能干细胞来源的间充质干细胞(iPSC ...
芦方娜
core
应用聚合酶链反应技术扩增血痕DNA,根据扩增产物中有无aPoB基因的数量可变重复序列(VNTR)及其扩增片段的大小即可同时确定其种属特异性和DNA的多态性。实验结果显示人血痕可见扩增带并具有多态性,而猴猪狗猫鸡血痕无扩增带。
doaj
利用动态图象高速微机采集系统,对纵向磁场线圈触头真空电弧形态进行了研究,触头开距从10mm到40mm变化,得出在相同电弧电流下,电弧扩散区域随开距增加而增加;电弧电压随开距增加而呈线性增加;弧柱电弧电场强度随开距增加而减少。这说明在长开距下,由于弧柱表面积增加,扩散到弧柱外的电子、离子和金属粒子相应增多,因而使输入到弧隙的能量增加以加热触头表面和加强粒子的扩散。
武建文, 王毅, 王季梅
doaj
An ultra-thin amniotic membrane preparation and its application as carrier in corneal epithelium tissue-engineering [PDF]
目的:羊膜是目前应用最广泛的构建组织工程角膜上皮的载体。但在临床应用中发现,基于羊膜构建的组织工程角膜上皮在移植术后角膜的透明度恢复并不理想。目前认为,羊膜基质的纤维细胞层及疏松的海绵层可能是影响羊膜透明度的主要原因。因此,本研究对传统去上皮羊膜(DAM)进行改造,制备一种新型的超薄羊膜(UAM)载体,并评估其生物学及光学性质,同时探讨使用该种载体构建组织工程角膜上皮的可行性。 方法:本研究利用0.02%的EDTA去除失活羊膜组织的上皮细胞,并采用IV型胶原酶消化去除羊膜基质的纤维层及海绵层 ...
张丽颖
core
Applying TALEN and CRISPR/Cas9 Technique to Knock out the PD1 Gene in Human Primary T Lymphocytes [PDF]
过继性细胞免疫治疗(adoptivecellularimmunotherapy)是将患者自体免疫细胞在体外处理,然后筛选并大量扩增具有高度特异性的肿瘤杀伤性免疫效应细胞,再回输到患者体内杀灭肿瘤的一种治疗方法,过继性T细胞治疗是一种很有前景的癌症治疗方法。体内T细胞在进行免疫应答时,T细胞活化需要双重信号的协同作用,分别是抗原呈递信号和协同刺激信号。协同刺激分子通过为淋巴细胞提供正性或负性的调控信号参与机体的免疫调控。肿瘤细胞会利用体内免疫调节过程,表达或分泌的一些分子,对T细胞进行负向调控 ...
李剑
core

