Results 1 to 10 of about 644,673 (177)

DDR1抑制剂与IGF-1R抑制剂联合应用及机制

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 2015
摘 要: 【目的】 研究盘状结构域受体(DDR1)的抑制剂3-(2-(吡唑并[1,5-a]嘧啶-6-基)乙炔基)苯甲酰胺7RH对鼻咽癌细胞的体外抗肿瘤作用及相关机制,为该药用于鼻咽癌的临床治疗提供实验依据。【方法】 采用MTT法绘制细胞生长曲线,计算7RH对鼻咽癌细胞的半数抑制浓度(IC50值);Western Blot检测7RH引起鼻咽癌细胞中信号通路的改变,并检测SiRNA瞬时转染方法干扰DDR1后phospho-IGF-1R的改变。【结果】 7RH在体外明显抑制鼻咽癌细胞的增殖并且呈浓度依赖性 ...
doaj   +1 more source

天然气水合物新型抑制剂的研究进展

open access: yes, 2004
概述了天然气水合物新型抑制剂相对于传统的热力学抑制剂的优点,介绍了新型抑制剂的类型、发展现状、抑制机理和常用抑制剂的合成及新型抑制剂的结合使用 ...
唐翠萍, 樊栓狮
core   +4 more sources

聚乙烯吡咯烷酮抑制水合物生成研究

open access: yes, 2006
对聚乙烯吡咯烷酮(PVP)在4℃、8.27MPa附近压力下对天然气水合物的抑制性能进行了实验,结果表明,PVP可以明显抑制水合物的生成,但不同分子量段的PVP有着不同的抑制效果:PVPK17因为分子量太小,几乎没有抑制作用;PVPK30有一定的抑制作用;而PVPK90则有着很好的抑制效果,能在实验条件下抑制1200min没有水合物的生成。另外发现,不同浓度的PVP对天然气水合物的抑制效果也不相同:对于PVPK30,1%浓度比0.5%浓度的抑制效果好;而对于PVPK90,则1%浓度的抑制效果比0.5%和2%
唐翠萍, 樊栓狮
core   +4 more sources

Cantonese (Dis)investment by Cross‐Border Postgraduates in Hong Kong: Negotiating Competing Capitals and Multiple Identities Among Neoliberal Subjects

open access: yesInternational Journal of Applied Linguistics, EarlyView.
ABSTRACT One key strategy that local universities and the government of Hong Kong have adopted in recent years is attracting more students from Chinese Mainland to study at Hong Kong's higher education institutions and contribute to society after graduation.
Lingnan Zhang, Yue Peng
wiley   +1 more source

Fighting Corruption Through Accountability? A Survey Experiment 感覺課責能否抑制貪腐?來自調查實驗的證據

open access: yesPublic Administration, EarlyView.
ABSTRACT Democratic Weberian bureaucracy is facing great challenges upholding public values as we see turbulent party politics disrupt merit‐based systems, causing bureaucrats' goal displacement and conflicting compliance under multiple accountability mechanisms.
Ming‐feng Kuo, Hsini Huang
wiley   +1 more source

Synergistic Defect Passivation and Phase Separation Suppression for Efficient Wide‐Bandgap Perovskite and Tandem Photovoltaics

open access: yesRare Metals, Volume 45, Issue 11, November 2026.
ABSTRACT Wide‐bandgap perovskite solar cells (WBG PSCs) have attracted significant attention as the top cell in tandem perovskite solar cells. However, the complexity of the composition leads to challenges such as defect formation and phase separation during the crystallization process, which impose significant constraints on the power conversion ...
Suzhen Liu   +9 more
wiley   +1 more source

Synergistic Enhancement of Creep Performance in Al19Co21Fe20Ni40 Eutectic High‐Entropy Alloy by Coupling Heterostructure Design With Boron‐Assisted Interfacial Optimization

open access: yesRare Metals, Volume 45, Issue 11, November 2026.
ABSTRACT This study systematically investigates the creep behavior of an Al19Co21Fe20Ni40 eutectic high‐entropy alloy (EHEA) at 500°C, focusing on the synergistic effects of heterostructure design and trace boron doping. Thermomechanical processing was employed to produce a heterostructure consisting of alternating lamellar and equiaxed regions.
Xudong Liu   +7 more
wiley   +1 more source

Pore‐Defect Synergistic Decoupling of Electrical and Thermal Transport in Entropy‐Engineered Thermoelectric Ceramics

open access: yesRare Metals, Volume 45, Issue 11, November 2026.
ABSTRACT Pore engineering reduces the thermal conductivity of thermoelectric materials, yet typically degrades electrical conductivity by enhancing carrier scattering—a long‐standing trade‐off. Here, we overcome this trade‐off in SrTiO3‐based entropy‐engineered ceramics via a one‐step synergistic strategy: using poly(methyl methacrylate) (PMMA) as a ...
Ziyao Wei   +7 more
wiley   +1 more source

天然气水合物新型动力学抑制剂抑制性能研究

open access: yes, 2008
提出了一种组合天然气水合物动力学抑制剂GHI1(聚乙烯吡咯烷酮(Inhibex157)与二乙二醇丁醚按1:1的质量比组合而成).在温度为4℃、压力为8.5~9.0MPa下的1.072L反应釜内,采用定容法,通过反应引起的温度和压力变化,研究了GHI1对天然气水合物形成的抑制性能,比较了不添加抑制剂、添加商用抑制剂Inhibex501、添加GHI1以及Inhibex157后的水合物大量生成时的温度变化,并分析了添加Inhibex501和GHI1后水合物大量生成时的时间,探讨了组合抑制剂的抑制机理 ...
唐翠萍   +6 more
core   +2 more sources

VFTO抑制新方法研究——高频过电压抑制导线

open access: yesGaoya dianqi, 2018
VFTO具有波前陡、幅值高、频带宽、持续时间长等特点,是GIS变电站及邻近电力设备安全的巨大威胁,必须采取措施对其进行抑制。现有的几种抑制方法均有一定的效果,也存在相应的缺陷。据此提出一种高频过电压抑制导线的设计。抑制导线由GIS母线改造的镂空螺线管及与之并联的电阻组成,安装方式与常规母线无异。在工频下,其正常进行电流、电压波的传输;当有高频过电压时,起抑制VFTO的作用。文中对高频过电压抑制导线抑制VFTO的机理进行了分析,说明了其抑制VFTO的优势。然后从抑制导线的结构分析其抑制VFTO的效果 ...
冯宇   +6 more
doaj  

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