Results 1 to 10 of about 2,767 (100)
Zhongshan Daxue xuebao. Yixue kexue ban, 2011 【目的】 加强对类风湿关节炎(RA)合并干眼症的认识，重视继发干燥综合征的早期诊断。【方法】 总结52例RA患者合并有眼干症状的临床特点，进行干眼三项试验；分析关节、血液沉降率(ESR)、抗核抗体谱、类风湿因子(RF)及免疫相关检查等。【结果】 52例中有干眼自觉症状者12例占23.1%，Schirmer试验阳性者39例(占75.0%)，BUT阳性者48例(占92.3%)，FL阳性者26例(占50.0%)，其中二项以上检查阳性者22例占(42.3%)；IgA、IgM&、IgG、IgE、C3 ...
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Giant Brunner’s gland adenoma of the duodenum complicated with bleeding: a case report [PDF]
, 2022 Brunner’s gland adenoma（BGA） of the duodenum is an extremely rare benign tumor in clinical practice. In this article， the diagnosis and treatment of one case of BGA of the duodenum were reported.
Xu Qi, Wang Yan, Tang Jing, Gao Fei, Zhang Jiewei, Zhuang Guifeng
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Clinical research on progress of antinuclear antibody in rheumatoid arthritis [PDF]
, 2023 Rheumatoid arthritis (RA) is a common chronic, systemic autoimmune disease characterized by erosive arthritis, with a global prevalence of 0.25% to 1.00%, which may ultimately lead to joint deformity and loss of function.
LI Yuan, ZHANG Le, YIN Hanlin, ZHENG Bing, LÜ Liangjing
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Zhongguo youzhi, 2023 为改善植物蛋白的溶解性并提升其抗氧化活性，选择核桃蛋白、小麦蛋白和芝麻蛋白为实验对象，在碱性条件下与核桃衣多酚相互作用，考察了核桃衣多酚改性对3种植物蛋白中性条件下的溶解度和抗氧化活性的影响。此外，通过SDS-PAGE、圆二色光谱和荧光光谱对溶出蛋白质的结构变化进行表征。结果表明：在核桃衣多酚添加量为75 mg/g时，核桃蛋白、小麦蛋白和芝麻蛋白在中性条件下的溶解度分别提升了61.54、 61.23、69.25百分点；同时，添加核桃衣多酚改性后的核桃蛋白 ...
黄子林，陈思蕊，孔祥珍，张彩猛，华欲飞，陈业明，李兴飞HUANG Zilin，CHEN Sirui，KONG Xiangzhen，ZHANG Caimeng， HUA Yufei，CHEN Yeming，LI Xingfei
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Zhejiang Daxue xuebao. Lixue ban, 2003 合成3种双核铂类配合物[{Pt(H2O)2I}μ—OOC—(CH2—)nCOO—{Pt(H2O)2I}](1~3)(n=0,1,2).用元素分析、摩尔电导、差热热重分析、红外光谱、紫外光谱和核磁共振氢谱等方法对其进行了表征.体外抗肿瘤活性表明,配合物1和3对多种人的肿瘤细胞有较高的活性,配合物2没有抗肿瘤活性.
ZHANGJin-chao(张金超) +6 more
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Establishment and evaluation of nomogram for differential diagnosis of systemic lupus erythematosus based on laboratory indications [PDF]
Objective·To establish a nomogram for the differential diagnosis of early systemic lupus erythematosus (SLE) and other autoimmune diseases based on laboratory indications, and to evaluate its efficacy.Methods·A total of 535 SLE patients admitted to the ...
CHEN Liubao +4 more
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一例补体抑制剂治疗欠佳的再生障碍性贫血-阵发性睡眠性血红蛋白尿患者的多学科诊疗分析 [PDF]
一例青年男性患者诊断再生障碍性贫血伴阵发性睡眠性血红蛋白尿(paroxysmal nocturnal hemoglobinuria，PNH)，经免疫抑制剂治疗后仅部分缓解。近1年贫血加重、输血依赖，考虑PNH活动性溶血所致，更换依库珠单抗治疗后贫血仍持续加重。详细询问病史发现患者慢性牙周感染，近1个月牙周疼痛溢脓伴发热。多学科讨论考虑慢性牙源性感染激活补体系统是PNH溶血加重的主要原因，急性感染影响了依库珠单抗的疗效。经多学科会诊制定治疗方案，给予静脉抗生素联合牙周冲洗、拔牙控制牙源性感染 ...
刘寅冬 +8 more
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Adult-onset Still's disease complicating late pregnancy: a case report and literature review [PDF]
Adult-onset Still's disease (AOSD) is a rare autoinflammatory disorder characterized by nonspecific clinical manifestations and the absence of definitive laboratory markers.
CHEN Kai +3 more
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Zhejiang Daxue xuebao. Lixue ban, 2005 首次合成两种二水羧酸根合铂类配合物[Pt(II)(H2O)2(OOC—CH2NH2)2](1)和[Pt(II)(H2O)2(OOC—CH=CHCOO)](2).用元素分析、摩尔电导、差热热重分析、红外光谱、紫外光谱和核磁共振氢谱对其进行了表征.体外抗肿瘤活性表明，两种配合物对所试的肿瘤细胞表现出较低的活性，在10 µM浓度下配合物对人膀胱癌细胞EJ的增殖抑制率分别为25.77% 和28.27%.
ZHANGJin-chao(张金超) +4 more
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Zhongguo shiyan zhenduanxue, 2023 感染性疾病(infectious disease)是由病原微生物引起的疾病的统称，目前仍然是全球公共卫生重大威胁，传统的病原学诊断方法已不能满足临床诊断和治疗的需要[1]。与传统病原学诊断方法(培养、质谱法、免疫相关抗原抗体检测和核酸检测技术等)比较，宏基因组学的二代测序(mNGS)是一种非靶向广谱病原学筛查技术，近几年发展迅猛已广泛应用于感染性疾病病原微生物的精准诊断，特别是在危重、疑难、罕见、新发病原体导致感染的诊断。
胡丽玲, 杨晓云, 郑纺
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