Results 11 to 20 of about 337 (67)
Rare Metals, Volume 45, Issue 9, September 2026.ABSTRACT Diabetic chronic wounds, characterized by a unique pathological microenvironment including persistent hyperglycemia, excessive reactive oxygen species (ROS), bacterial infection, and sustained inflammation, exhibit notoriously impaired and delayed healing processes. This study developed a multifunctional hydrogel therapeutic system (GOx@Zn‐MPN
Baowei Zhai +11 more
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Rare Metals, Volume 45, Issue 9, September 2026.ABSTRACT Ti‐15Mo‐2.5Ag alloy exhibited a low modulus and strong antibacterial ability but poor bioactivity. To resolve this problem, sandblasting and anodization were used to create a hydrophilic and nano‐Ag2O‐containing TiO2 coating. Subsequently, the microstructure and physicochemical properties were investigated by scanning electron microscopy, X ...
Yanchun Xie +11 more
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四川大学学报. 自然科学版, 2009 利用抗生素耐药性突变,从12株天然无抗菌活性或活性微弱的放线菌中筛选活性菌株,共获得752株突变菌株。通过抑菌活性测定,筛选得到一株野生放线菌J22耐庆大霉素突变菌株,编号为J22-G6。该突变菌株具有强烈的抗细菌活性和较好的传代稳定性。该突变菌株在菌株形态方面与原始菌株有一定的差异。试验证明突变菌株J22-G6具有更强的耐受庆大霉素的能力。分析初步推定J22-G6所产生的抗菌活性物质为聚醚类化合物。
方丽萍 +3 more
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Rare Metals, Volume 45, Issue 8, August 2026.ABSTRACT Due to their exceptional porosity, structural versatility, and modular coordination chemistry, metal–organic frameworks (MOFs) have emerged as versatile platforms for targeted drug delivery. These structures enable fine‐tuning of pore size, surface activity, and framework stability for the encapsulation of a broad range of therapeutics ...
Rui Hua +9 more
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四川大学学报. 自然科学版, 2006 对健康大口鲇皮肤分泌液蛋白组分进行了分析,SDS-PAGE电泳表明其中有17种蛋白质.用饱和硫酸铵分级沉淀法发现在20%50%的饱和度之间沉淀出来的蛋白有抗菌活性.该抗菌蛋白对G+和G-菌有广谱抗菌活性,在pH 5～8范围内稳定,并且在100℃下作用10min后活性依然稳定.同时检测了患病大口鲇重要组织提取液的抗菌活性,为进一步研究健康大口鲇抗菌蛋白奠定了基础.
袁媛 +7 more
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Rare Metals, Volume 45, Issue 8, August 2026.ABSTRACT The healing of diabetic chronic wounds is hindered by multiple pathological barriers, including oxidative stress imbalance induced by hyperglycemia, persistent bacterial infection, and impaired neovascular function. This study developed an F127–HA–BiOCl@CeO2 (FHBC) hydrogel dressing with acoustic responsiveness, achieving tissue repair through
Ran Zhao +8 more
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Zhongshan Daxue xuebao. Yixue kexue ban, 2002 【目的】评价抗菌药物辅助治疗活动期中、重度慢性溃疡性结肠炎的疗效。【方法】对有关抗菌药物辅助治疗活 动期中、重度慢性溃疡性结肠炎的前瞻性临床试验进行Meta 分析。【结果】抗菌药物辅助治疗的有效率比安慰剂高9 %～ 28 %, 平均高18%, 效率差异有显著性(P
林 王莹, 朱兆华
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Rare Metals, Volume 45, Issue 8, August 2026.ABSTRACT Advanced metallic glasses, leveraging their ultrahigh strength, excellent corrosion resistance, superior soft magnetic properties and good biocompatibility, have gradually become indispensable strategic cornerstones in critical fields such as aerospace, electronic information and energy power. This unique combination of properties enables them
Yizhou Liu +11 more
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四川大学学报. 自然科学版, 2001 采用聚丙烯酰胺凝胶电泳分离纯化兔中性粒细胞防御素，兔中性粒细胞防御素ＮＰ２具有抗白念珠菌Ｍ１０１２Ｒ，ＮＩＨ Ａ－２０７，乳酒念珠菌，热带念珠菌和高里氏念珠菌等菌的活性，且抗菌活性随防御素浓度的升高而增强．
蒋献 +4 more
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Zhongguo youzhi旨在高值化利用青刺果榨油后副产物青刺果粕中的蛋白质，以青刺果粕为原料，提取青刺果蛋白并制备蛋白酶解物，采用活菌吸附法联合反相高效液相色谱（RP-HPLC）从蛋白酶解物中筛选出抗菌肽组分，评价其抑菌活性，并对抑菌活性最好的组分进行稳定性分析。结果表明：筛选出的3个抗菌肽组分（F1、F2和F3）中，F2组分抑菌活性最好，当其质量浓度为10 mg/mL时对金黄色葡萄球菌和大肠杆菌的抑菌活性分别达到45.5%和39.1%；抗菌肽组分F2抑菌活性随温度升高和盐溶液浓度增加均降低，最适pH为6.0 ...
朱薪,康山明,张天雄,王雪峰，范江平,普岳红 ZHU Xin, KANG Shanming, ZHANG Tianxiong, WANG Xuefeng, FAN Jiangping, PU Yuehong
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