Results 11 to 20 of about 7,164 (135)

Comparison between clinical evaluations and laboratory findings and the impact of biofilm on antimicrobial susceptibility in vitro in canine otitis externa

open access: yesVeterinary Dermatology, Volume 34, Issue 6, Page 586-596, December 2023., 2023
Background – In clinical practice, the diagnosis of otitis externa (OE) normally is based on otoscopic examination and cytological findings, followed by empirical treatment with topic drugs. Biofilm‐producing bacteria are frequently present in OE, even if its presence is often underdiagnosed. Hypothesis/Objectives – The primary aim of this study was to
Luca Luciani   +6 more
wiley   +1 more source

Trichophyton mentagrophytes complex: A retrospective study of 64 dogs from the Central United States (1997–2020)

open access: yesVeterinary Dermatology, Volume 34, Issue 4, Page 310-317, August 2023., 2023
Background – There are limited clinical studies evaluating the Trichophyton mentagrophytes complex, with most reports confined to small case studies. Additionally, the studies are dated and provide limited information on response to newer or currently available therapies.
Jason B. Pieper   +5 more
wiley   +1 more source

Bacteriophage and Fusidic Acid Have Synergistic Effect Against Meticillin‐Resistant Staphylococcus pseudintermedius in Ex Vivo Canine Dermis Model

open access: yesVeterinary Dermatology, Volume 37, Issue 2, Page 200-210, April 2026.
Background: Antimicrobial stewardship has become vital given the progressive emergence of multidrug‐resistant bacteria, and novel approaches to the treatment of bacterial infections are needed. Recently, reported synergistic effects of antibacterial drugs and bacteriophage therapy have revealed promising applications for the management of meticillin ...
Sarah Ehling   +9 more
wiley   +1 more source

Advances in Elemene Nanodelivery Systems: From Material Design to Disease Treatment

open access: yesRare Metals, Volume 45, Issue 2, February 2026.
ABSTRACT Elemene (ELE) is a bioactive sesquiterpenoid extracted from traditional Chinese herbs, demonstrating broad‐spectrum antitumor, anti‐inflammatory, and analgesic properties with significant therapeutic potential. However, its clinical utility is constrained by inherent physicochemical limitations, including volatility and hydrophobicity, which ...
Xiao Wang   +9 more
wiley   +1 more source

术中抗菌药物使用情况调查分析 [PDF]

open access: yes, 2013
目的了解某院手术在抗菌药物的应用情况,为合理用药提供参考。方法不定期地进入医院手术室,抽取在台手术病历,填写患者的基本信息及用药调查表。输入EXCEl表,进行统计分析并院内通报。结果在301份病历中,抗菌药物的使用率:61.46%(185/301),治疗性使用抗菌药物17例,预防性使用抗菌药物168例,联合用药4例。应用抗菌药物种类以头孢类为主,达132例次(77.84%)。抗菌药物使用合理率:77.41%(234/301)。结论医院手术中抗菌药物使用基本合理,但存在预防用药使用率偏高、选药不当等不足 ...
于阗, 陈华漫
core  

Optimization of β lactam antibiotics regimens against bloodstream infection caused by Pseudomonas aeruginosa [PDF]

open access: yes, 2017
目的制定某院B内酰胺类在铜绿假单胞菌(PA)血流感染中的治疗方案。方法收集某院2015年至2016年血培养中铜绿假单胞菌共64株,测定B内酰胺类(哌拉西林/他唑巴坦,头孢他啶,头孢吡肟,亚胺培南,美罗培南)对铜绿假单胞菌的最低抑菌浓度(MIC)。用蒙特卡洛模拟计算多种治疗方案的达标率(PrA)和累积反应分数(CFR)。结果经验治疗时,哌拉西彬他唑巴坦4.5g(q6h),头孢他啶2g(q8h),头孢吡肟2g(q8h),亚胺培南1g(q6h),美罗培南1g(q8h,q6h),共6种方案的CFR值〉90 ...
于迪   +4 more
core   +1 more source

NIR‐Responsive Nano‐Integrated Magnesium Phosphate Cement Promotes Bone Regeneration via Osteoblast‐Exosome‐Osteoclast Crosstalk

open access: yesRare Metals, Volume 45, Issue 2, February 2026.
ABSTRACT The limited osteogenic capacity of magnesium phosphate cement (MPC) has constrained its biomedical applications, underscoring the necessity to develop MPC with enhanced physical properties and bone‐forming capabilities. In this study, a multifunctional MPC system was developed by incorporating zoledronic acid‐loaded near‐infrared (NIR ...
Bin Wang   +8 more
wiley   +1 more source

883例术中抗菌药物使用情况调查分析 [PDF]

open access: yes, 2015
不定期地进入医院手术室,抽取在台手术病历,填写患者的基本信息及用药调查表。输入EXCEl表,进行统计分析并院内通报。在883份病历中,抗菌药物的使用率:62.51%(552/883),治疗性使用抗菌药物30例,预防性使用抗菌药物522例,联合用药5例。应用抗菌药物种类以头孢类为主,达460例次(88.12%)。抗菌药物使用合理率:81.31%(718/883)。说明我院手中抗菌药物使用基本合理,但存在预防用药使用率偏高、选药不当等不足 ...
于阗, 陈华漫
core  

Distribution of blood culture pathogens and clinical characteristics in children with acute leukemia complicated with septic shock [PDF]

open access: yes, 2022
Objective To explore the distribution of blood culture pathogens and clinical characteristics in children with acute leukemia complicated with septic shock.
Liu Tinghua, Lei Jiaying, Mai Yougang
core   +1 more source

Single Cold Atmospheric Plasma Therapy May Improve the Treatment Outcome of Canine Otitis Externa With Secondary Infection

open access: yesVeterinary Dermatology, Volume 37, Issue 1, Page 103-110, February 2026.
Background: Otitis externa with secondary bacterial or yeast infection is a common problem in small animal practice. Cold physical plasma (CPP) has been reported to have antimicrobial activity in vitro. Results: Ears treated additionally with CPP showed lower otic scores after 21 days compared to nontreated ears, although this difference was not ...
Ralf S. Mueller, Cosima Bouassiba
wiley   +1 more source

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