Results 11 to 20 of about 7,164 (135)
Background – In clinical practice, the diagnosis of otitis externa (OE) normally is based on otoscopic examination and cytological findings, followed by empirical treatment with topic drugs. Biofilm‐producing bacteria are frequently present in OE, even if its presence is often underdiagnosed. Hypothesis/Objectives – The primary aim of this study was to
Luca Luciani +6 more
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Background – There are limited clinical studies evaluating the Trichophyton mentagrophytes complex, with most reports confined to small case studies. Additionally, the studies are dated and provide limited information on response to newer or currently available therapies.
Jason B. Pieper +5 more
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Background: Antimicrobial stewardship has become vital given the progressive emergence of multidrug‐resistant bacteria, and novel approaches to the treatment of bacterial infections are needed. Recently, reported synergistic effects of antibacterial drugs and bacteriophage therapy have revealed promising applications for the management of meticillin ...
Sarah Ehling +9 more
wiley +1 more source
Advances in Elemene Nanodelivery Systems: From Material Design to Disease Treatment
ABSTRACT Elemene (ELE) is a bioactive sesquiterpenoid extracted from traditional Chinese herbs, demonstrating broad‐spectrum antitumor, anti‐inflammatory, and analgesic properties with significant therapeutic potential. However, its clinical utility is constrained by inherent physicochemical limitations, including volatility and hydrophobicity, which ...
Xiao Wang +9 more
wiley +1 more source
目的了解某院手术在抗菌药物的应用情况,为合理用药提供参考。方法不定期地进入医院手术室,抽取在台手术病历,填写患者的基本信息及用药调查表。输入EXCEl表,进行统计分析并院内通报。结果在301份病历中,抗菌药物的使用率:61.46%(185/301),治疗性使用抗菌药物17例,预防性使用抗菌药物168例,联合用药4例。应用抗菌药物种类以头孢类为主,达132例次(77.84%)。抗菌药物使用合理率:77.41%(234/301)。结论医院手术中抗菌药物使用基本合理,但存在预防用药使用率偏高、选药不当等不足 ...
于阗, 陈华漫
core
Optimization of β lactam antibiotics regimens against bloodstream infection caused by Pseudomonas aeruginosa [PDF]
目的制定某院B内酰胺类在铜绿假单胞菌(PA)血流感染中的治疗方案。方法收集某院2015年至2016年血培养中铜绿假单胞菌共64株,测定B内酰胺类(哌拉西林/他唑巴坦,头孢他啶,头孢吡肟,亚胺培南,美罗培南)对铜绿假单胞菌的最低抑菌浓度(MIC)。用蒙特卡洛模拟计算多种治疗方案的达标率(PrA)和累积反应分数(CFR)。结果经验治疗时,哌拉西彬他唑巴坦4.5g(q6h),头孢他啶2g(q8h),头孢吡肟2g(q8h),亚胺培南1g(q6h),美罗培南1g(q8h,q6h),共6种方案的CFR值〉90 ...
于迪 +4 more
core +1 more source
ABSTRACT The limited osteogenic capacity of magnesium phosphate cement (MPC) has constrained its biomedical applications, underscoring the necessity to develop MPC with enhanced physical properties and bone‐forming capabilities. In this study, a multifunctional MPC system was developed by incorporating zoledronic acid‐loaded near‐infrared (NIR ...
Bin Wang +8 more
wiley +1 more source
不定期地进入医院手术室,抽取在台手术病历,填写患者的基本信息及用药调查表。输入EXCEl表,进行统计分析并院内通报。在883份病历中,抗菌药物的使用率:62.51%(552/883),治疗性使用抗菌药物30例,预防性使用抗菌药物522例,联合用药5例。应用抗菌药物种类以头孢类为主,达460例次(88.12%)。抗菌药物使用合理率:81.31%(718/883)。说明我院手中抗菌药物使用基本合理,但存在预防用药使用率偏高、选药不当等不足 ...
于阗, 陈华漫
core
Distribution of blood culture pathogens and clinical characteristics in children with acute leukemia complicated with septic shock [PDF]
Objective To explore the distribution of blood culture pathogens and clinical characteristics in children with acute leukemia complicated with septic shock.
Liu Tinghua, Lei Jiaying, Mai Yougang
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Background: Otitis externa with secondary bacterial or yeast infection is a common problem in small animal practice. Cold physical plasma (CPP) has been reported to have antimicrobial activity in vitro. Results: Ears treated additionally with CPP showed lower otic scores after 21 days compared to nontreated ears, although this difference was not ...
Ralf S. Mueller, Cosima Bouassiba
wiley +1 more source

