Results 41 to 50 of about 2,331 (166)
The Role of Steroid Receptor Coactivator 3 in Atherosclerosis [PDF]
, 2016 目的：动脉粥样硬化是动脉壁对炎症的损伤性反应，是多种细胞及因子相互作用的结果，但目前的发病机制仍不清楚。血管内皮损伤、脂质代谢紊乱、炎症反应在其发生发展中都扮演重要角色。类固醇受体辅激活因子3不仅能抑制甘油三酯向肝外转运，而且在炎症应答中扮演着重要角色，目前SRC-3在动脉粥样硬化中的研究还未曾报道，我们的研究旨在揭开SRC-3对动脉粥样硬化的影响的具体机制。方法：确定动脉粥样斑块的血管SRC-3表达量增高后，我们获取APOE-/-、SRC-3-/-敲除小鼠和APOE-/-、SRC-3+/+小鼠 ...
苏强
core
Integrative Conservation, Volume 4, Issue 3, Page 287-301, September 2025.Qilianshan National Park covers approximately 40% of core snow leopard habitat patches and 50% of movement corridors between patches. Including more of these important areas within the park boundaries should be considered, as the Qilianshan National Park sits at a pivotal juncture between critical snow leopard habitat in China and Mongolia, and may ...
Aliana Norris +6 more
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2015 彩色多普勒高频颈动脉超声检查,对临床预测颈动脉狭窄程度、评估斑块成分提供了有效的手段[1]。斑块内有无出血发生、有无溃疡形成及斑块的增长速度是决定斑块稳定性的重要因素。高血压水平与心脑血管事件的风险评估,易损斑块的发生率的预测是预防高血压的关键[2]。本研究采用高频超声评价对老年高血压水平与颈动脉斑块关系,及时发现颈动脉易损斑块 ...
邱文风, 聂颖, 李素英, 景文宝
doaj
Zhongguo cuzhong zazhi, 2019 【摘要】 目的 利用颈动脉高分辨率磁共振成像（high resolution MRI，HR-MRI）技术分析急性脑梗死患者颈内动脉角（internal carotid artery angle，ICAA）与动脉粥样硬化斑块形态学特点，探讨ICAA与动脉粥样硬化斑块形态的关系。 方法 入组2011年11月-2012年6月的急性颈内动脉系统脑梗死患者，行颈动脉HR-MRI检查，获得每例患者左右侧ICAA及动脉粥样硬化斑块形态资料。根据ICAA大小的中位数将颈动脉分为ICAA≥35°组和ICAA＜35°组，
王琳，王晶，申园，龚浠平，刘艳芳
doaj +1 more source
Effect of Ba Zhu Decoction(BZD) on the related mechanisms of Aβ formation in 5xFAD transgenic mice [PDF]
, 2016 目的：巴茱合剂是本人硕士导师治疗阿尔兹海默病(AD)的经验方，前期临床研究证明，巴茱合剂能有效缓解AD患者认知功能障碍，但对巴茱合剂的作用机制尚未深入研究。本文旨在通过AD转基因动物再次验证巴茱合剂的治疗效果，并进一步探索巴茱合剂治疗AD的相关分子生物学机制。 方法：（1）选取新型APP/PS1转基因小鼠(5xFAD小鼠)作为实验对象。将3月龄5xFAD小鼠随机分为模型组(5xFAD-Control)、巴茱合剂低剂量组(5xFAD-BZD-L)、中剂量组(5xFAD-BZD-M)、高剂量组(5xFAD ...
彭阿香
core
Integrative Conservation, Volume 4, Issue 3, Page 345-353, September 2025.Restoration of monoculture in protected and marginal areas can be organized into two phases (1) identification and prioritization of restoration sites based on remote sensing or field survey then assessing degradation level, and (2) implementation of appropriate restoration interventions.
Liang Song +9 more
wiley +1 more source
Simvastatin inhibit glucose uptake through insulin receptor dependent IRS1/PI3K/Akt pathway in mouse myotubes [PDF]
, 2015 他汀类药物是羟甲基戊二酸单酰辅酶A(3-hydroxy-3-methylglutaryl-CoA，HMG-CoA)还原酶抑制剂，可竞争性抑制内源性胆固醇的合成。大量研究表明长期服用他汀类药物可增加新发糖尿病的发病风险，但具体机制尚不清楚。 本实验使用辛伐他汀及胆固醇代谢中间产物甲羟戊酸内酯干预小鼠骨骼肌细胞(由小鼠成肌细胞C2C12细胞分化而来)，采用免疫印迹法（immunoblotting）、流式细胞术、细胞毒性试验和葡萄糖消耗试验，研究辛伐他汀和甲羟戊酸内酯对骨骼肌细胞葡萄糖代谢的影响及其作用机制 ...
梁晓静
core
Wildlife Letters, Volume 3, Issue 3, Page 91-98, September 2025.The edge densities of cropland, developed land, and water bodies (panel a) predict the spatial probability of mammalian predation on wild turkeys (panel b) using Mahalanobis distance factor analysis in Quitman County, Mississippi, United States. The three habitat fragmentation variables are represented by three arrows, respectively.
Guiming Wang +2 more
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2011 颈动脉粥样硬化斑块与缺血性脑卒中密切相关,而斑块的不稳定性是其危险性的最重要因素。因此对于颈动脉粥样硬化斑块稳定性的研究尤为重要。本研究应用速度向量成像（VVI）技术初步分析颈动脉粥样硬化斑块受力后的形变特点,探讨该项技术在评价斑块力学状态方面的应用价值 ...
冯海艳 +5 more
doaj
Æ E Æ Å – Reshaping the Role of Træna Fishermen
, 2022 This diploma project aims to strengthen the viability of Træna’s community by proposing an ocean research facility in the archipelago, enabling the next generation of local fishermen to collect oceanographic data while working at sea. The idea of the fisherman as oceanographer is inextricably linked to the architectural program on the island of ...
openaire +1 more source