The role of circadian rhythm and its new strategies for prevention and treatment in oral diseases [PDF]
Circadian rhythm is a biological endogenous process regulated by the suprachiasmatic nucleus of the hypothalamus, which transmits light signals to peripheral clocks and synchronizes the body with the external environment through balanced expression of ...
WANG Yajun, ZHANG Lin, CHENG Chen, XING Wenmin, GE Xuejun, CHENG Fengli, ZHANG Fang
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Study on Circadian rhythm and clock genes in Microcystis aeruginosa PCC7820 [PDF]
, 2007 生物钟是广泛存在于蓝藻、植物和动物细胞中的内源计时系统，它对各种代谢和行为的实时调控使机体能更好地适应环境日变化（如光照、温度和湿度等）。生物钟一般具有三个主要特点，即在稳恒条件下生物钟仍然能以近似24h的周期自由运行；光/暗和温度信号能重置生物钟时相；生物钟周期长度具有温度补偿性。 蓝藻是具有生物钟的最简单生物，当其生物钟周期与环境光/暗周期相近时，藻细胞具有更强的生存竞争优势。生物钟这种内源计时系统在蓝藻中普遍存在，并且能全面调控细胞代谢，如细胞分裂，固氮作用、光合作用、氨基酸吸收 ...
徐虹
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The Effects of EA-ACR Promoting Plasma Melatonin of Insomnia Rats induced by PCPA [PDF]
, 2016 失眠是现如今临床常见的一种睡眠障碍性疾病，也越来越受到全球范围的重视。目前对失眠的研究大多集中于临床研究中，而针对失眠的基础机制研究很少，还有待进一步完善。 褪黑素是近几年来研究较多的与失眠密切相关的一种激素。为了进一步探讨失眠的病理机制，本实验共选用36只雄性SD大鼠，采用PCPA腹腔注射致失眠模型，用耳甲区电针刺激的方法，通过测定大鼠体重、旷场试验及血浆褪黑素分泌水平变化，从而探讨耳甲区电针调节失眠大鼠睡眠情况的机制。 结果：（1）PCPA腹腔注射28-30h后,大鼠睡眠出现昼夜节律性改变 ...
徐伟伟
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野生动物学报, 2020 利用红外相机技术，对宁夏罗山国家级自然保护区夏、秋两季赤狐（Vulpes vulpes）的活动节律进行了研究。结果表明，赤狐在不同月份的日活动差异指数α（t=18359，df=5 ...
李涛 1 孟德怀 2 滕丽微 2 +2 more
doaj
Lipidomic Analysis of the Effect of Piperine on Circadian Rhythm of Lipid Metabolism-Associated Genes in Obese Rats [PDF]
In this study, an obese rat model induced by a high-fat diet (HFD) was used to investigate the modulating effect of 1-piperoylpiperidine (PIP) on circadian misalignment caused by metabolic dysregulation. The results showed that PIP attenuated HFD-induced
ZHANG Weiyun, HO Chi-Tang, LÜ Muwen
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Effect of DBP inhibition on vascular calcification in chronic uremic rats [PDF]
, 2022 Objective To evaluate the effect of D-site binding protein （DBP） inhibition on vascular calcification in chronic uremic rats. Methods GSE146638 was downloaded from the public database （Gene Expression Omnibus， GEO）， and a total of 10 samples from rat of ...
Cao Sujuan, Liu Shuzheng, Yuan Buqi, Yuan Peile, Zhao Songhe, Zhang Yunfang
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Zhongguo shiyan zhenduanxue, 2015 昼夜节律是与人体关系最为密切的生物节律之一,近年来临床医生越来越重视昼夜节律对药物作用效果的影响[1-4]。时间药理学研究指出,同一组织或是器官对于相同剂量的同一种药物在不同时间时段,药物敏感性和作用效果是有差异的。咪达唑仑是一种在临床麻醉和ICU镇静中被广泛应用的苯二氮卓类短效中枢神经抑制剂,具有抗焦虑、催眠、抗惊厥和顺行性遗忘作用。目前已有研究证实昼夜节律对异丙酚、氯胺酮、戊巴比妥 ...
王岩, 叶虹, 王庆波
doaj
Regulatory Effect and Mechanism of Capsaicin on the Circadian Rhythm of Hepatic and Pancreatic Glucose Metabolism in High-Fructose and High-Fat Diet-Fed Mice [PDF]
In this study, the modulatory effect of capsaicin (CAP) on the circadian rhythm of glucose metabolism in the liver and pancreas of mice fed a high-fructose and high-fat diet (HFFD) was investigated.
HAN Liguang, LIANG Wanxia, WANG Wenshuo, XIAO Jie, HO Chi-Tang, Lü Muwen
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Iurnal Variability of Airway Hyperresponsiveness in Asthma Patients [PDF]
, 2022 BackgroundThere are daytime variability in pulmonary function indexes such as peak expiratory flow (PEF) and forced expiratory volume in 1 second (FEV1) in asthma patients.
YU Xinxin, ZHENG Jinping, GAO Yi, XIE Yanqing, AN Jiaying, LIU Wenting, ZHONG Liping, WU Zhongping, ZHU Zheng
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Effects of two intermittent fasting strategies on postprandial lipid metabolism in adults [PDF]
ObjectiveTo investigate the effects and potential mechanisms of morning and evening fasting on postprandial lipid responses, a post hoc analysis based on a crossover randomized controlled trial was conducted to assess the effects of different fasting ...
HE Gengsheng +6 more
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