Results 11 to 20 of about 32,470 (201)
Studies on the antidepressant-like effect and prokinetic-like effects and the underlying mechanisms of Fructus aurantii and meranzin hydrate [PDF]
, 2016 目的：测定代表中药枳壳汤剂抗抑郁促动力(A&P)的吸收成分，初步阐明其A&P特别是抗抑郁的作用机理。 方法：1.含量测定。运用HPLC/MS/MS测定枳壳汤剂在空肠，海马和前额叶皮层吸收成分；2.急性抗抑郁疗效测试。该实验包括枳壳汤剂及其吸收成分水合橙皮内酯的急性抗抑郁疗效测试。该测试包括强迫游泳实验、旷场实验、习得性无助实验和新奇抑制实验；3.水合橙皮内酯的慢性抗抑郁疗效测试。包括强迫游泳实验和旷场实验；4.离体和在体胃肠动力实验；5.抗抑郁机制研究和抗抑郁促动力的共性机制研究 ...
柳进
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Justice in coexistence: Pastoralism and large carnivores on the Qinghai‐Tibet Plateau
People and Nature, EarlyView.Abstract The conflict between livestock husbandry and large carnivore conservation presents significant challenges in grassland ecosystems worldwide. Achieving sustainable coexistence among herders, livestock and large carnivores requires reconciling diverse perspectives and interests through equitable, inclusive and fair processes that address both ...
Yufang Gao, Yue Yu
wiley +1 more source
Molecular mechanism of inhibitory effect of lipoxin A4 on estrogen-induced epithelial to mesenchymal transition (EMT) in endometriosis [PDF]
, 2016 子宫内膜异位症，简称内异症（Endometriosis，EM），是育龄妇女的常见病，它是指具有活性的子宫内膜出现在子宫腔以外所引起的一种病变。人群发病率高达10%-15%。其典型症状为不孕和疼痛，严重影响患者的生活质量和家庭和谐，尤其是高达50%的复发率，给家庭和社会带来沉重的经济负担。这一系列防治难题的根本原因在于发病机制尚不明确。解析内异症的发病机制，进而寻找新的药物靶点和安全高效的治疗方法具有重大意义。 本论文首先以临床内异症患者在位/异位子宫内膜组织及非内异症患者子宫内膜组织为研究对象 ...
吴荣锋
core
Wildlife Letters, EarlyView.Tracking with GPS and accelerometers shows that great evening bats in subtropical China use two overwintering strategies: some remain in continuous hibernation, while others switch between torpor and activity as temperatures change. This behavioral flexibility, shaped by climate, underscores the importance of protecting diverse roosting habitats for ...
Zhiqiang Wang +7 more
wiley +1 more source
The Role and Mechanism of Dihydroartemisinin in the Development of Non-Small Cell Lung Carcinoma [PDF]
, 2016 背景及目的 肺癌是最常见的恶性肿瘤，在全世界范围内，也是肿瘤导致死亡的首位原因。非小细胞肺癌是肺癌最常见的一种类型。非小细胞肺癌细胞对凋亡的抵抗性是抗肿瘤治疗的一大主要的障碍。因此，目前研究关注的热点是那些能提高治疗抵抗非小细胞肺癌细胞凋亡的新型复合物的发展。双氢青蒿素是一种重要的青蒿素衍生物，是从中草药植物青蒿素中提取出来的天然产物。作为一种非常有效的抗疟疾药物，双氢青蒿素（DHA）在全世界范围内已经是治疗抗疟原虫的一线治疗药。近期研究发现DHA对乳腺癌，乳头瘤病毒导致的宫颈癌 ...
李春雷
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Functional Ecology, EarlyView.Read the free Plain Language Summary for this article on the Journal blog. Abstract Root exudates play a key role as signals and nutrients in mediating plant–microbe communication. However, critical knowledge gaps remain regarding how root exudates mediate soil–microbe–plant interactions to regulate crop yield under long‐term straw mulching combined ...
Jiajie Song +7 more
wiley +1 more source
Functional Ecology, EarlyView.Read the free Plain Language Summary for this article on the Journal blog. Abstract Ecological communities are stressed by rapid and complex anthropogenic changes, threatening the persistence of biotic interactions and ecosystem functioning. Plant–pollinator communities, for instance, undergo structural transformations as a result of land‐use change ...
Erliang Gao +8 more
wiley +1 more source
全球能源互联网, 2020 火电灵活性改造，特别是降低机组最小稳定功率，可有效增强系统调峰能力，缓解弃风弃光问题。但灵活调节需求随风光电源、负荷和电网运行特性动态变化而难以准确估计，火电厂易陷入过度投资或无序竞争的两难抉择而延迟乃至放弃改造，导致实际改造容量远低于国家规划预期。因此，如何在保证可再生能源消纳目标前提下科学规划火电机组的灵活性改造容量成为地区能源管理部门和火电厂共同关注的问题。首先建立了包括机组改造成本、调峰市场交易成本、售电收益损失、深调状态发电成本增量和系统弃电成本五部分费用在内的火电机组灵活性改造广义成本模型 ...
徐昊亮 +4 more
doaj +1 more source
Analysis on the Impact and the Transmission Mechanism of the Global Oil Price Fluctuations on Chinese Agricultural Products Market [PDF]
, 2016 本文是在当前国际政治经济形势复杂多变，国际石油市场激烈震荡，而我国石油对外依存度持续攀升的形势下展开的一项全新的、富有战略意义的研究。长期以来，我国现行的成品油定价机制难以与国际油价保持一致，导致国内成品油价涨快跌慢、涨多跌少。国内大部分农产品价格难以形成市场化的自动调节机制，国际油价与农产品价格之间的传导滞后，国内资本市场的投机和套利行为也因此增多。随着我国农产品期货市场逐渐成熟，商品价格指数体系的建立与不断完善为本文研究国际油价波动对我国农产品市场的影响与传导机制提供了有力的条件 ...
曲旭芹
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Comprehensive framework for assessing and optimizing existing research networks
Conservation Biology, EarlyView.Abstract Conservation, monitoring, and research networks, or collections of ecological research sites unified under a common mission of data collection or a research mission, are essential infrastructure for understanding large landscapes. However, most networks developed opportunistically over decades rather than through systematic design, creating ...
Alyson East +2 more
wiley +1 more source