Results 1 to 10 of about 2,143 (105)
Emergency management and the final frontier: Preparing local communities for falling space debris
Abstract Global dependence on satellite technologies, along with expanding space exploration, and commercial space travel have made rocket launches routine modern‐day events. As a result, there is an increasing probability of civilian casualty from rocket launch anomalies, or from falling space debris already in orbit.
Hans M. Louis‐Charles +3 more
wiley +1 more source
Effect of Life Review Therapy for Holocaust Survivors: A randomized controlled trial
Abstract Despite the therapeutic needs of aging Holocaust survivors, no randomized controlled trial (RCT) of psychotherapy exists for this population, with very few on older adults in general. This RCT aimed to compare the efficacy of Life Review Therapy for Holocaust survivors (LRT‐HS) relative to a supportive control group. Holocaust survivors with a
Simon Forstmeier +6 more
wiley +1 more source
Background– Pseudomonas aeruginosa (PA) may cause suppurative otitis externa with severe inflammation and ulceration in dogs. Multidrug resistance is commonly reported for this organism, creating a difficult therapeutic challenge. Objective– The aim of this study was to evaluate the in vitro antimicrobial activity of a gel containing 0.5 µg/mL of ...
Giovanni Ghibaudo +6 more
wiley +1 more source
携带AFP的rAAV感染树突状细胞对肝癌细胞杀伤作用的实验研究
目的探讨携带甲胎蛋白(AFP)的重组腺相关病毒(rAAV)感染树突状细胞(DCs)对肝癌细胞株SMMC-7721的体外杀伤作用,为肝癌非手术治疗提供方法。方法首先确定AFP基因序列并合成AFP基因,将其转染至重组腺相关病毒rAAV,之后将转染AFP的rAAV感染树突状细胞,并将感染rAAV的DC与SMMC-7721共同培养,同时设未感染rAAV的DC作为对照组,用MTT法检测rAAV-DC及DC对SMMC-7721的杀伤活性。结果感染rAAV的DC对SMMC-7721的杀伤活性为89.00 ...
王斌 +5 more
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Biodegradable Mg Alloys: Enhancing Anti‐tumor Immunity in Cancer Therapy
ABSTRACT Magnesium (Mg) alloys, as biodegradable metallic materials with excellent biocompatibility and mechanical properties, demonstrate significant advantages. In the field of immunotherapy, they present a promising potential option for enhancing therapeutic outcomes and hold broad prospects for application.
Can Feng +8 more
wiley +1 more source
ABSTRACT This study introduces novel nonequiatomic TiZrCoCrMoCux (x = 0, 5, 10; at%) medium‐entropy alloys (MEAx) tailored for orthopedic implants, synergistically combining the biocompatibility of Ti‐based alloys, the wear resistance of CoCrMo alloys, and the antibacterial/osteogenic attributes of Cu. The alloy's microstructure, mechanical properties,
Hang Yu +9 more
wiley +1 more source
目的探讨DC(dendritic cells)、CIK(cytokine-induced killer cells)联合培养对肺腺癌细胞A549的杀伤活性的影响,并与单独CIK对A549杀伤活性进行比较,为肿瘤生物治疗提供有效方法。方法分别培养DC、CIK细胞,经鉴定后进行联合培养,联合培养3天后,对A549细胞进行杀伤活性实验,检测DC联合CIK及单独CIK对A549的杀伤活性,同时用流式细胞检测DC、CIK联合培养细胞及单独CIK细胞中淋巴细胞亚群的表达。结果 ...
赵鑫 +8 more
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目的以CpG ODN为免疫佐剂激活人外周血单个核细胞(PBMC),观察激活的PBMC对肿瘤细胞的杀伤活性。方法分别以肿瘤抗原(Ag)、白细胞介素-2(IL-2)和CpG ODN单独或联合刺激正常人和肿瘤患者PBMC,测定其对肿瘤细胞的杀伤活性。结果以CpG ODN刺激人PBMC组的细胞,其对肿瘤细胞的杀伤活性明显高于对照组 ...
韩刚, 李金龙, 贾明库
doaj
CpG ODN刺激PBMC后作用于卵巢癌细胞HO8910杀伤活性的研究
目的探讨合成含CpG基序的寡核苷酸(CpG ODN)在肿瘤免疫治疗中的研究。方法将CpG ODN刺激体外培养的人外周血单个核细胞(PBMC)后作用于卵巢癌细胞株(HO8910),采用MTT法检测其杀伤活性。结果加CpGODN组较单独PBMC组杀伤活性明显增高 ...
吴富菊, 马晓艳, 魏敏, 薛惠荣
doaj
目的探讨慢性心力衰竭(CHF)患者自然杀伤细胞(NK)活性的变化。方法选择NYHAⅡ-Ⅳ级的CHF患者48例作为观察组,30例健康查体者作为对照组。测定全血NK细胞数目和血清、培养上清中白细胞结素6(IL-6)含量,并测定NK细胞杀伤活性。结果(1)CHF患者循环NK细胞和NK细胞杀伤活性显著降低,并与心衰程度呈负相关(r=-0.873,-0.949 ...
谭晓玉
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