High glucose induces pro-inflammatory polarization of macrophages by inhibiting immune-responsive gene 1 expression. [PDF]
Luo W, Wang Y, Liu Y, Wang Y, Ai L.
europepmc +1 more source
nIL-33介导的巨噬细胞极化在口腔鳞状细胞癌中的作用及机制研究进展
口腔鳞状细胞癌(OSCC)是世界范围内最常见的头颈部恶性肿瘤,OSCC的发生与口腔黏膜的癌前病变密切相关。巨噬细胞是黏膜免疫的重要参与者,通过调控不同表型的极化状态促进OSCC进展。核白细胞介素-33(nIL-33)通过调控细胞线粒体代谢重塑巨噬细胞极化。本文系统综述巨噬细胞与口腔鳞癌进展的关系,从细胞核-线粒体调控极化表型角度阐明巨噬细胞极化自我调控机制,以期为靶向巨噬细胞抗OSCC治疗提供思路和参考。
王娜 +5 more
doaj
[Layered double hydroxide-loaded si-NEAT1 regulates paclitaxel resistance and tumor-associated macrophage polarization in breast cancer by targeting miR-133b/PD-L1]. [PDF]
Zhang Z +8 more
europepmc +1 more source
[Sulforaphane reverses Aβ fiber-mediated M1 type microglia polarization and neuroinflammation-mediated necroptosis of neural stem cells by downregulating the MAPK/NF-κB signaling pathways]. [PDF]
Zhang J +10 more
europepmc +1 more source
[Mechanisms of Neiyiting Decoction in Preventing Postoperative Recurrence of Endometriosis by Inhibiting Macrophage M1 Polarization Through the TREM1/TLR4/NF-κB Signaling Pathway]. [PDF]
Lu L +9 more
europepmc +1 more source
Noggin alleviates neuropathic pain by regulating microglial polarization and remodeling iron homeostasis via a STAT3-dependent pathway. [PDF]
Zhang W, Yang L, Zhang R.
europepmc +1 more source
[Ecliptasaponin A ameliorates DSS-induced colitis in mice by suppressing M1 macrophage polarization <i>via</i> inhibiting the JAK2/STAT3 pathway]. [PDF]
Niu M +8 more
europepmc +1 more source

