Results 1 to 10 of about 635,200 (143)

慢性乙肝和慢性重型乙肝患者血单核细胞Toll 样受体2的变化

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 2008
【目的】 探讨慢性乙型肝炎和慢性重型乙型肝炎患者外周血单核细胞Toll样受体2(TLR2)的变化情况及其意义。【方法】 随机选取慢性乙型肝炎患者31例,设定为慢性乙型肝炎组,慢性重型乙型肝炎患者30例设定为慢性乙型肝炎组,健康志愿者30例为正常对照组,用流式细胞仪检测各组外周血单核细胞表面Toll样受体2的表达,ELISA法检测血清肿瘤坏死因子α(TNF-α)的水平,荧光定量PCR法检测血清HBV DNA并取对数作为复制水平的指标,总胆红素(TB)和凝血酶原时间(PT)的检测按照本院常规检测 ...
尉秀清, 崇雨田, 文卓夫
doaj   +1 more source

The effect of a mixed cannabidiol and cannabidiolic acid based oil on client‐owned dogs with atopic dermatitis

open access: yesVeterinary Dermatology, Volume 33, Issue 4, Page 329-e77, August 2022., 2022
Background– Cannabidiol (CBD) and cannabidiolic acid (CBDA) are reported to have antinociceptive, immunomodulatory and anti‐inflammatory actions. Objectives – To determine if CBD/CBDA is an effective therapy for canine atopic dermatitis (cAD). Conclusions and clinical relevance – Cannabidiol/CBDA as an adjunct therapy decreased pruritus, and not skin ...
Melissa Loewinger   +4 more
wiley   +1 more source

Act A-FS系统表达水平在急慢性心肌损伤中的变化及意义

open access: yesZhongguo shiyan zhenduanxue, 2021
目的旨在探讨炎症因子activin(Act)A与其结合蛋白Follistatin(FS)在急性心肌梗死(AMI)与慢性心力衰竭(CHF)患者血清中的水平变化及其来源与意义。方法应用ELISA法检测AMI组、CHF组及健康对照组血清Act A与FS水平,应用实时定量RT-PCR检测各组患者外周血单个核细胞Act A与FS mRNA表达,应用化学法Griess试剂测定各组患者外周血一氧化氮。结果 AMI组血清activin A水平明显高于CHF组,CHF组显著高于健康对照组;AMI组血清FS水平升高 ...
杨春艳, 闫晓雨, 贺玉泉, 杨萍
doaj  

International clinical practice recommendations on the definition, diagnosis, assessment, intervention, and psychosocial aspects of developmental coordination disorder – Chinese (Mandarin) translation

open access: yesDevelopmental Medicine &Child Neurology, Volume 61, Issue 3, Page E1-E35, March 2019., 2019
目的 本国际临床指南由欧洲残疾儿童学会(the European Academy of Childhood Disability,EACD)牵头制定,旨在解决发育性协调障碍(developmental coordination disorder,DCD)的定义、诊断、评估、干预以及与社会心理方面的临床应用关键问题。 方法 本指南针对五个领域的关键问题,通过文献综述和专家团队的正式讨论达成共识。为保证指南的循证基础,以“机制”、“评估”和“干预”为检索词, 对2012年更新以来提出的最新建议以及新增的“社会心理问题”和“青少年/成人”为检索词进行检索。根据牛津大学循证医学中心证据等级 (证据水平 [level of evidence, LOE]1–4) 将结果进行分类,最终转化为指南建议。并由国际 ...
Jing Hua   +6 more
wiley   +1 more source

基于清单编制法的中国碳市场免费碳配额分布平衡分析 [PDF]

open access: yes全球能源互联网, 2022
生态环境部于2020年印发了发电行业免费碳配额设定与分配实施方案,为控排企业免费碳配额核算提供了标准。目前全国碳市场已启动运行,此前对中国免费碳配额分配的分析均引用了大量假设,且计算精度有限。为此,编制了全国火电厂级精细度的碳清单,自下而上地辨识全国火电厂级煤耗、产能参数,并根据发电行业免费碳配额标准,计算以2020年为基准的碳清单,以此研究目前碳市场规则下免费碳配额在火电行业中的分配平衡性,对于分析现阶段碳市场运行状况、评价碳市场对电力系统的经济影响具有参考价值。分析结果表明 ...
赵宏兴   +5 more
doaj   +1 more source

Developmental plasticity drives converge nt shifts in phosphorus acquisition strategies towards root phosphatase activity in Moso bamboo under nitrogen addition

open access: yesFunctional Ecology, Volume 40, Issue 7, Page 2221-2236, July 2026.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Anthropogenic nitrogen (N) deposition is a major driver of global change. However, its effects on the developmental plasticity of plant nutrient strategies remain poorly understood.
Quan Li   +11 more
wiley   +1 more source

Changing fish invasion patterns associated with community fish species turnover in 15 Chinese plateau lakes

open access: yesFunctional Ecology, Volume 39, Issue 10, Page 2743-2757, October 2025.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Biological invasions threaten both biodiversity and ecosystem functioning, yet the role of functional and phylogenetic relationships between invaders and the recipient community in invasion success remains controversial.
Songhao Ji   +7 more
wiley   +1 more source

Next‐Generation Sequencing of Fecal DNA: A Novel Insight Into the Mitogenome Phylogeography of the Snow Leopard (Panthera Uncia) 粪便dna的二代测序:对雪豹线粒体组谱系地理结构的新洞察

open access: yesIntegrative Conservation, Volume 4, Issue 3, Page 277-286, September 2025.
This study provides an innovation to address the challenge in accessibility to samples and genetic markers in Snow leopard conservation genetic studies. We performed next‐generation sequencing (NGS) on 19 fecal samples obtained from the eastern Qinghai‐Tibet Plateau, and successfully assembled 17 complete mitogenome sequences (~16,720 bp) and ...
Chen Cheng   +7 more
wiley   +1 more source

Fetal lower urinary tract obstruction: international Delphi consensus on management and core outcome set

open access: yesUltrasound in Obstetrics &Gynecology, Volume 64, Issue 5, Page 635-650, November 2024.
ABSTRACT Objectives To reach an international expert consensus on the diagnosis, prognosis and management of fetal lower urinary tract obstruction (LUTO) by means of a Delphi procedure, and to use this to define a core outcome set (COS). Methods A three‐round Delphi procedure was conducted among an international panel of experts in fetal LUTO.
H. J. Mustafa   +90 more
wiley   +1 more source

EB病毒血清学及DNA联合检测在婴幼儿传染性单核细胞增多症临床应用研究

open access: yesZhongguo shiyan zhenduanxue, 2015
目的探讨实时定量PCR技术对传染性单核细胞增多症婴儿的诊断价值。方法选取临床表现为发热的婴儿442例,其中48例传染性单核细胞增多症患儿为观察组,另选择50例健康儿童为对照组,应用实时定量PCR技术(RT-qPCR)检测外周血EB病毒DNA载体,对患儿进行外周血异型淋巴细胞及血清嗜异凝集反应,并对单个细胞EBV-DNA载量进行检测,全面对比分析EBV-DNA诊断的诊断效果。结果 1EBV-DNA阳性患儿中异型淋巴细胞>10%患儿39例,占69.6%,血清嗜异凝集反应阳性患儿37例,占66.1%;EBV ...
孙志惠, 刘鹏
doaj  

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