Results 101 to 110 of about 7,085 (155)

长链非编码核糖核酸及其介导的竞争内源性核糖核酸与卒中发病机制研究进展

Zhongguo cuzhong zazhi, 2019
陆小燕，范存秀，杜冰滢，刘振宇，毕晓莹
doaj   +1 more source

[Comprehensive analytical chemistry experiment： analysis of non-covalent interactions between double-stranded deoxyribonucleic acid and a natural drug by electrospray ionization mass spectrometry]. [PDF]

Se Pu
Ma L, Wang YH, Yuan YL, Wang SS.
europepmc   +1 more source

[Advances in mapping analysis of ribonucleic acid modifications through sequencing]. [PDF]

Se Pu
Xiong J, Feng T, Yuan BF.
europepmc   +1 more source

[Ferroptosis-related long non-coding RNA to predict the clinical outcome of non-small cell lung cancer after radiotherapy]. [PDF]

Beijing Da Xue Xue Bao Yi Xue Ban
Xu Q, Liu T, Wang J.
europepmc   +1 more source

HO-1在AMPK抑制心肌肥大中的作用

Zhongshan Daxue xuebao. Yixue kexue ban, 2010
目的】 研究AMP激活的蛋白激酶 (AMPK)及血红素氧合酶HO-1激活对心肌肥大的影响,以及HO-1在AMPK抑制心肌肥大中的作用?【方法】 以培养的新生大鼠心肌细胞为研究对象,采用蛋白免疫印迹杂交方法检测5-氨基-4甲酰胺咪唑核糖核苷酸(AICAR)对AMPK的磷酸化程度及对HO-1的影响,并测定心肌细胞 [3H]-亮氨酸掺入率及心肌细胞表面积,观察AMPK及HO-1心肌细胞肥大的影响?【结果】 AICAR对AMPK及HO-1均有激活作用,AICAR能阻断AngⅡ引起的心肌肥大效应;阻断HO ...
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[Effect and mechanism of astaxanthin on the aging of high glucose-treated human skin fibroblasts]. [PDF]

Zhonghua Shao Shang Yu Chuang Mian Xiu Fu Za Zhi
Tang LJ, Fan LH, Wang JR, Luo M, Yang XX, Zhong RQ, Gao HY.   +6 more
europepmc   +1 more source

PCR技术用于检测肝细胞癌石蜡包埋肝组织中的HBV DNA

Zhongshan Daxue xuebao. Yixue kexue ban, 1993
用多聚酶链反应(PCR)技术检测了16例肝细胞性肝癌(HCC)患者癌灶和癌旁双份组织石蜡包埋标本中的乙型肝炎病毒脱氧核糖核酸(HBV-DNA)。以C基因引物扩增HBV-DNA,32份标本中检出率71.87％。以新鲜冷冻肝标本作对照检出率81.25％,二者相比无显著性差别(X~=0.57,P>0.05)。以质粒提取HBV-DNA作灵敏度测定,PCR-EB可达10fg,PCR-SBH可达lag。应用非放射性的地高辛素标记探针作杂交灵敏度达~32P标记探针的水平。
doaj  

[Research progress of hydrogel-based growth factors for treatment of intervertebral disc degeneration]. [PDF]

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi
Huo X, Li Z.
europepmc   +1 more source

激活核因子Ｅ２相关因子２信号通路减轻高糖诱导足细胞的凋亡

Zhongshan Daxue xuebao. Yixue kexue ban, 2013
【目的】 探讨激活核因子Ｅ２相关因子２（Ｎｒｆ２）通路能否减轻高糖诱导足细胞的凋亡。【方法】体外培养小鼠足细胞，分为５组：对照组、高渗组、高糖组、高糖＋叔丁基对苯二酚（ ｔＢＨＱ），高糖＋Ｎ－乙酰半胱氨酸（ＮＡＣ）。流式细胞仪检测细胞内活性氧和凋亡；Ｗｅｓｔｅｒｎ ｂｌｏｔ 及ｒｅａｌ ｔｉｍｅ－ ＰＣＲ检测Ｎｒｆ２、醌氧化还原酶１（ＮＱＯ１），血红素加氧酶（ＨＯ－１）的表达；检测足细胞丙二醛（ＭＤＡ）、超氧化物歧化酶（ＳＯＤ）、谷胱甘肽（ＧＳＨ）及过氧化氢酶（ＣＡＴ）。【结果】 高糖组足细胞凋亡率 ...
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[Progress in metabolomics of multiple myeloma]. [PDF]

Zhonghua Xue Ye Xue Za Zhi
Ye X, Sun ZX, Qu XY, Fan L.
europepmc   +1 more source