[Research progress of hydrogel-based growth factors for treatment of intervertebral disc degeneration]. [PDF]
Huo X, Li Z.
europepmc +1 more source
[Research progress on the quercetin target role and signaling pathway in anti-liver fibrosis]. [PDF]
Zhao RQ +9 more
europepmc +1 more source
目的】 研究AMP激活的蛋白激酶 (AMPK)及血红素氧合酶HO-1激活对心肌肥大的影响,以及HO-1在AMPK抑制心肌肥大中的作用?【方法】 以培养的新生大鼠心肌细胞为研究对象,采用蛋白免疫印迹杂交方法检测5-氨基-4甲酰胺咪唑核糖核苷酸(AICAR)对AMPK的磷酸化程度及对HO-1的影响,并测定心肌细胞 [3H]-亮氨酸掺入率及心肌细胞表面积,观察AMPK及HO-1心肌细胞肥大的影响?【结果】 AICAR对AMPK及HO-1均有激活作用,AICAR能阻断AngⅡ引起的心肌肥大效应;阻断HO ...
doaj
【目的】 探讨激活核因子E2相关因子2(Nrf2)通路能否减轻高糖诱导足细胞的凋亡。【方法】体外培养小鼠足细胞,分为5组:对照组、高渗组、高糖组、高糖+叔丁基对苯二酚( tBHQ),高糖+N-乙酰半胱氨酸(NAC)。流式细胞仪检测细胞内活性氧和凋亡;Western blot 及real time- PCR检测Nrf2、醌氧化还原酶1(NQO1),血红素加氧酶(HO-1)的表达;检测足细胞丙二醛(MDA)、超氧化物歧化酶(SOD)、谷胱甘肽(GSH)及过氧化氢酶(CAT)。【结果】 高糖组足细胞凋亡率 ...
doaj
[Progress in metabolomics of multiple myeloma]. [PDF]
Ye X, Sun ZX, Qu XY, Fan L.
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[Advances in the Regulation of Protein Phosphorylation in Streptococcal Cell Wall Synthesis]. [PDF]
Yi S, Peng X, Wang S.
europepmc +1 more source
[Exercise-induced hyperinsulinism: genetic basis and clinical management]. [PDF]
Zhang QT, Hou L.
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[Research progress on lactylation modification in pathogenesis of osteoarthritis]. [PDF]
Wu Y +7 more
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[Clinical research advances for small-molecule nucleic acid drugs in the treatment of chronic hepatitis B]. [PDF]
Wang WX +4 more
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[Research Progress on Quorum Sensing-Regulated Oral Microbial Interaction Networks in Periodontitis]. [PDF]
Li L, Yu Z, Xu Y.
europepmc +1 more source

