Results 11 to 20 of about 22,262 (188)

Virulence gene distribution and molecular epidemiological characteristics of carbapenem-resistant Klebsiella pneumoniae in the ICU. [PDF]

Zhong Nan Da Xue Xue Bao Yi Xue Ban
目的 碳青霉烯耐药肺炎克雷伯菌(carbapenem-resistant Klebsiella pneumoniae，CRKP)携带的耐药基因会限制临床用药选择，其毒力基因也会严重影响患者预后。本研究旨在探讨重症监护室(intensive care unit，ICU) CRKP的毒力基因分布、荚膜血清型及分子流行病学特征，了解ICU中CRKP的感染特点，为ICU有效监测和防控CRKP感染提供科学依据。 方法 ...
Huang Y, Cai Y, He W, Zhang L, Zhao Y.
europepmc   +2 more sources

ABCA12 Frameshift Deletion in Domestic Cats With Ichthyosis Fetalis

Veterinary Dermatology, EarlyView.
ABSTRACT Background Ichthyosis fetalis (IF), also known as harlequin ichthyosis, is a rare and often fatal autosomal recessive congenital skin disorder. It is characterized by thickened, hard skin plaques and deep skin fissures that limit mobility and cause malformations of the eyes, lips and ears.
Jeanna M. Blake, Melissa P. Swan, Kari J. Ekenstedt   +2 more
wiley   +1 more source

Tolerability and Feasibility of Minimally Invasive Canine Skin Sampling: Excellent Tolerability Meets Transcriptomic Challenges

Veterinary Dermatology, EarlyView.
ABSTRACT Background Advances in transcriptomics have driven the demand for minimally invasive, reproducible and high‐yield skin sampling methods, particularly for studying inflammatory skin diseases in companion animals. Hypothesis/Objectives We tested tolerability, feasibility and RNA quantity and quality of three minimally invasive skin sampling ...
Ina Herrmann, Lisa B. Mamo, Allison N. Dickey   +2 more
wiley   +1 more source

World Association for Veterinary Dermatology Consensus Statement for Diagnosis, and Evidence‐Based Clinical Practice Guidelines for Treatment and Prevention of Canine Leishmaniosis

Veterinary Dermatology, Volume 36, Issue 6, Page 723-787, December 2025.
Hyperkeratosis of (a) the footpads and (b) the nasal planum. ABSTRACT Background Canine leishmaniosis (CanL) due to Leishmania infantum remains common, and veterinarians do not always follow scientifically sound approaches for diagnosis, treatment and prevention. Objectives To provide consensus guidelines for diagnosis and evidence‐based guidelines for
Manolis N. Saridomichelakis, Gad Baneth, Silvia Colombo, Filipe Dantas‐Torres, Lluís Ferrer, Alessandra Fondati, Guadalupe Miró, Laura Ordeix, Domenico Otranto, Chiara Noli   +9 more
wiley   +1 more source

Prenatal evaluation, diagnosis and management of fetal corpus callosal abnormalities: international Delphi consensus

Ultrasound in Obstetrics &Gynecology, Volume 66, Issue 5, Page 582-588, November 2025.
ABSTRACT Objective The corpus callosum (CC) is an interhemispheric structure that facilitates communication between the two cerebral hemispheres. Anomalies of the CC are frequent and associated with a wide spectrum of altered neurodevelopmental outcomes.
R. Corroenne, D. Paladini, I. Papastefanou, R. Chaoui, L. Pomar, L. Guibaud, K. Krajden Haratz, R. K. Pooh, M. Herrera, R. Ximenes, G. Azumendi, G. Pilu, L. J. Salomon, Collaborators, G. Turkyilmaz, D. L. Rolnik, W. Sepulveda, G. Rizzo, R. Llorens, S. Meagher, B. Tutschek, M. Aertsen, S. Agarwal, T. Tarui, E. Scola, D. Pretorius, A. Henry, J. Binder, E. R. Guzman, C. Rodo, A. Schiattarella, K. Grossman, S. Bakalis, J. Pascual‐Mancho, E. Eixarch, P. Galati, D. Bittencourt Sodré Barmpas, M. Savvidou, B. M. E. Adriaanse, M. T. Izquierdo, V. Cecotti, N. Sananès, D. Muresan, D.‐G. Iliescu, V. Faure‐Bardon, R. Has, C. Batukan, S. Ahmet Erol, A. Seval Ozgu‐Erdinc, B. Kapudere, E. Toprak, M. Akalin, S. Özeren, H. Golbasi, B. Kaya, B. Strizek   +55 more
wiley   +1 more source

Effect of aspirin on maternal hemodynamics in Chinese women at high risk for preterm pre‐eclampsia: longitudinal study

Ultrasound in Obstetrics &Gynecology, Volume 66, Issue 5, Page 621-630, November 2025.
ABSTRACT Objectives To compare the maternal hemodynamics of Chinese women at low and at high risk for preterm pre‐eclampsia (PE) and assess the differences in hemodynamic parameters between high‐risk women with or without prophylactic aspirin. Methods This was a prospective longitudinal case–control study of 857 Chinese women with a singleton pregnancy
X. Wang, J. Lin, Y. Chen, I. S. Wong, J. Liu, F. Liu, S. L. Lau, Q. Zhang, X. Xu, D. S. Sahota, A. P. W. Lee, L. C. Poon   +11 more
wiley   +1 more source

Synopsis of the antimicrobial use guidelines for canine pyoderma by the International Society for Companion Animal Infectious Diseases (ISCAID)

Veterinary Dermatology, Volume 36, Issue 5, Page 552-565, October 2025.
Abstract Background Canine pyoderma is one of the most common presentations in small animal practice, frequently leading to antimicrobial prescribing. Objectives To provide clinicians with antimicrobial treatment guidelines for staphylococcal pyoderma, including those involving meticillin‐resistant staphylococci.
Anette Loeffler, Christine L. Cain, Lluís Ferrer, Koji Nishifuji, Katarina Varjonen, Mark G. Papich, Luca Guardabassi, Siân M. Frosini, Emi N. Barker, Scott J. Weese   +9 more
wiley   +1 more source

Validation of the Parental Reflective Functioning Questionnaire in Finnish mothers and fathers of toddlers

Infant Mental Health Journal: Infancy and Early Childhood, Volume 46, Issue 5, Page 564-576, September 2025.
Abstract Parental reflective functioning (PRF) is important in guiding parenting behavior. It is traditionally measured with interviews that are relatively time‐consuming. A self‐report measure of PRF, the Parental Reflective Functioning Questionnaire (PRFQ), has been developed but has not yet been extensively validated across different sociocultural ...
Marjo Flykt, Hannu Haarala, Kirsi Pyhältö, Jaana Minkkinen, Mirjam Kalland   +4 more
wiley   +1 more source

Investigation of the Role and Mechanism of Rapamycin on Senile Osteoporosis via Osteocyte Autophagy [PDF]

, 2016
背景：老年性骨质疏松症患病人数逐年攀升，已成为严重的公共卫生问题。最新研究表明：骨细胞通过调节成骨细胞和破骨细胞的功能，从而主导骨重建。随着年龄增长，骨细胞凋亡增加，数目减少，导致骨代谢紊乱。细胞自噬是一种重要的生理机制，可以协助维持骨细胞活性。研究表明，因年龄增加而导致的骨细胞自噬功能障碍与老年性骨质疏松症的发病密切相关。因此，本课题以骨细胞自噬为切入点，选取经典的自噬诱导剂雷帕霉素，探究其对于老年性骨质疏松症的作用及可能机制。 方法：将52只24月龄SD大鼠随机分为雷帕霉素组和对照组 ...
罗德庆
core  

Implications of Tobacco Use on Pathogen‐Driven Diseases: A Public Health and Policy Perspective

World Medical &Health Policy, Volume 17, Issue 3, Page 468-474, September 2025.
ABSTRACT The tobacco epidemic remains one of the most significant global public health challenges, responsible for over 8 million deaths annually, with a substantial portion occurring among non‐smokers exposed to second‐hand smoke. While cigarette smoking remains the most prevalent form of tobacco use worldwide, the rise of electronic nicotine delivery
Nadine Kabbani, James L. Olds
wiley   +1 more source