Results 11 to 20 of about 47,871 (257)

Cloning and sequencing of protein C activator gene from Agkistrodon blomhoffii brevicaudus(江浙蝮蛇蛇毒蛋白C激活因子基因的克隆及测序)

open access: yesZhejiang Daxue xuebao. Lixue ban, 2003
从江浙蝮蛇毒腺中抽提总RNA,RT-PCR进行体外扩增,获得江浙蝮蛇蛇毒蛋白C激活因子基因,克隆至pGEx-5x-3载体中.对3个重组克隆分别作DNA全序列分析,通过遗传密码推导出相应的氨基酸序列.与其它已知的丝氨酸蛋白酶型蛇毒蛋白的氨基酸作比较,其中许多位置上氨基酸有很强的同源性.该基因的成功克隆,不仅推导出江浙蝮蛇蛇毒蛋白C激活因子的蛋白质序列,也为进一步开展江浙蝮蛇蛇毒蛋白C激活因子蛋白质工程的研究工作打下良好的基础.
WANGYun-gui(王云贵)   +4 more
doaj   +1 more source

Study on focal points of fundamental research of sciences in Zhejiang Province during the "11th Five Year Program" through entropy analysis(基于熵值法的浙江省“十一五”基础研究热点分析与思考)

open access: yesZhejiang Daxue xuebao. Lixue ban, 2011
熵值法是一种科学、简单、实用的综合评价方法.由于熵值法是一种客观赋权法,因此可以避免人为因素带来的偏差.以浙江省“十一五”期间6个基础研究学科领域获得浙江省自然科学基金资助项目的情况作为数据源,采用熵值法对这些数据进行分析总结,揭示了浙江省在基础学科领域的研究热点,并据此对浙江省“十二五”期间基础学科领域的研究发展趋势进行了预测和思考.
LIZhi-lan(李志兰)
doaj   +1 more source

Hyperandrogenemia Induces Trophoblast Ferroptosis and Early Pregnancy Loss in Patients With PCOS via CMA‐Dependent FTH1 Degradation

open access: yesAdvanced Science, EarlyView.
In PCOS patients with hyperandrogenemia, decreased ferritin heavy chain 1 (FTH1) causes Fe2⁺ overload and ferroptosis in trophoblasts. Androgens induce FTH1 protein degradation via AR‐LAMP2A‐mediated chaperone‐mediated autophagy pathway, leading to placental development disruption and early pregnancy loss. Metformin mitigates androgen‐induced placental
Hanjing Zhou   +10 more
wiley   +1 more source

浙江省鸟类新纪录——赭红尾鸲

open access: yes野生动物学报, 2020
2019年4月在浙江象山韭山列岛国家级自然保护区发现1只赭红尾鸲雄鸟,经查询文献资料,确定为浙江省鸟类新纪录。
丁鹏 1, 陈冠 1, 范忠勇 2, 3
doaj  

Platelet Rubicon Bidirectional Regulation of GPVI and Integrin αIIbβ3 Signaling Mitigates Stroke Infarction Without Compromising Hemostasis

open access: yesAdvanced Science, EarlyView.
This study identifies Rubicon as a key platelet protein that bidirectionally regulates GPVI and integrin αIIbβ3 signaling. Platelet Rubicon protects against cerebral ischemia‐reperfusion injury by limiting infarction without increasing hemorrhage.
Xiaoyan Chen   +11 more
wiley   +1 more source

A Research on Mobile Terminal Promotion Based on Big Data of Zhejiang Telecom [PDF]

open access: yes, 2016
2008年,中国电信业进行了重组,全面形成了中国电信、中国移动、中国联通三家综合性运营商全业务营销的模式,同时也意味着中国电信业打破垄断经营机制,形成了全面竞争的格局。八年来,中国电信在面临三大运营商之间竞争不断加剧的势态的同时,持续加快3G和4G网络的建设,加大手机移动用户的发展,以终端引领移动业务的发展,在移动业务市场上占有了一席之地。 然而,受国家政策指引,通信行业的资费在不断进行下调,近年来陆续实施了接听免费、漫游资费下调、宽带资费下调、流量不清零等政策,使得话音、宽带 ...
王紫庄
core  

PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

open access: yesAdvanced Science, EarlyView.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao   +16 more
wiley   +1 more source

Solar‐driven co‐evolution of H2 and H2O2 from pure water splitting over emerging photocatalysts: Detailed mechanism and future outlook

open access: yesPhotoMat, EarlyView., 2023
Photocatalytic water splitting for co‐evolution of H2 and H2O2 is deemed as a sustainable and promising strategy to address energy and environment issues, thus receiving increasing attention and realizing continuous achievements. This review aims to offer a deep understanding of the mechanism for H2 and H2O2 co‐evolution and the design principle of ...
Qiaohong Zhu   +4 more
wiley   +1 more source

Trends of drought and flood in Zhejiang Province respond to climatic warming(浙江省汛期旱涝趋势对气候变暖的响应)

open access: yesZhejiang Daxue xuebao. Lixue ban, 2007
近50多年来浙江省气候变化总趋势在逐渐变暖,80年代中期开始变暖明显,增幅加大.浙江省汛期各月降水量对气候变暖的响应不同:在季节转换月份5月和9月,降水量明显减小,而在夏季的降水量增加,8月尤甚.在气候变暖期,浙江省汛期旱涝事件的发生频数增加.大气环流对气候变暖的响应是:5月份,高层南亚高压偏弱偏南,中国东南部上空为平直的西风气流,引导冷空气多偏北东移,中层印缅槽的减弱导致向江南水汽输送减少,低层偏南气流远离华东,浙江省主要受单一西北干燥气流影响,降水显著偏少;8月份,青藏高压位置偏西 ...
ZHONGYuan(钟元)   +3 more
doaj   +1 more source

ホウコク3 ミンコクキ コウセツ ニ オケル チセキ セイリ ジギョウ ノ サギョウ カテイ [PDF]

open access: yes, 2007
平成18 年度科学研究費補助金 基盤研究(A)1930年代広東省土地調査冊の整理・分析と活用(課題番号 17251006)中間報告書国際ワークショップ ...
稲田, 清一
core  

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