Results 61 to 70 of about 8,473 (140)
This review details a three‐stage paradigm shift for tumor‐reactive CD8+ T‐cell identification: decoding transcriptomic states, deciphering clonal functional efficacy, and molecular‐level therapeutic TCR design. Addressing translational hurdles and generative AI “scientific blind spots”—such as missing catch bonds—we present a visionary roadmap.
Chao Yang +4 more
wiley +1 more source
为探究山莨菪碱在浸泡免疫大黄鱼中的应用效果,以添加山莨菪碱佐剂的杀香鱼假单胞菌灭活疫苗浸泡免疫大黄鱼,结果显示,免疫后1~4周,无佐剂疫苗组(FKC组)和山莨菪碱疫苗组(FKCA组)血清抗体水平均显著升高,第2~3周FKCA组血清抗体显著高于FKC组。rt-PCR结果显示,从免疫后第4天开始,头肾、脾脏中免疫因子IgM、IL-1β、MHC-Iα、MHC-IIβ、CD4、CD8的表达量均出现升高,FKCA组头肾中IgM、IL-1β、MHC-Iα、CD8的表达峰值显著高于FKC组。酶活结果显示 ...
李 姣姣 +6 more
doaj +1 more source
目的评价采用超临界二氧化碳脱细胞后动物源性骨修复材料的免疫原性和成骨能力。方法将猪股骨前处理后随机分成两组,分别使用常规方法(常规对照组)和超临界二氧化碳(实验组)进行脱细胞处理,并以同种脱钙骨基质作为阳性对照。通过酶联免疫吸附试验和荧光染色法检测半乳糖-α-1,3-半乳糖(α-Gal)抗原清除率和DNA残留量。9只6周龄SPF级雄性裸鼠随机分成实验组、常规对照组和阳性对照组,在裸鼠股二头肌肌间隙中植入不同骨组织,术后4周取材,分别用苏木精-伊红(HE ...
郝 峰 +6 more
doaj +1 more source
ABSTRACT Repetitive motion planning (RMP) for redundant manipulators with high convergent precision becomes an intense research topic due to its more degrees of freedom. In this paper, a specific zeroing neural dynamics (SZND) model for the RMP is first set up via zeroing neurodynamics.
Ying Kong +3 more
wiley +1 more source
Screening of multiple acyl-CoA dehydrogenase deficiency in newborns and follow-up of patients. [PDF]
Zhou D +6 more
europepmc +1 more source
海上风电经24 脉动二极管整流器送出系统的交流滤波器优化配置 [PDF]
整流站采用二极管整流器能够提升远距离大容量海上风电直流送出系统的经济性和可靠性。提出了基于24脉动二极管整流器的海上风电并网系统中交流滤波器的优化配置方法。首先,明确了基于24脉动二极管整流器的海上风电送出系统结构,阐述了24脉动二极管整流器的基本原理。然后,计算了24脉动二极管整流器的无功功率需求,对于24脉动二极管整流器,可以将设计复杂的交流滤波器简化为电容器,通过对有功功率变化范围内不同容量电容器滤波效果进行扫描,提出了综合考虑滤波效果和滤波器容量的交流滤波器无功容量优化方法。最后,在PSCAD ...
黄晓明 +7 more
doaj +1 more source
For long years, patients and clinicians in Eastern China used Western data as information foundation for management and treatment of malignant mesothelioma, due to its rarity and lack of deep investigation. This study updated the epidemiological data of malignant mesothelioma in Eastern China, and revealed better survival outcomes compared to Western ...
Ningning Li +7 more
wiley +1 more source
Quantitative analysis of maxillary palatal masticatory mucosa thickness and anatomical morphology of palatal vault in Zhejiang province. [PDF]
Shen C, Gao B, Lyu K, Ye W, Yao H.
europepmc +1 more source
ABSTRACT Enzymatic modification using glycosyltransferases offers a green route to produce highly branched starch to enhance starch functionality in the food industry, yet this approach faces challenges including the high cost of enzyme production and inefficiency.
Feifei Xu +7 more
wiley +1 more source
黄腹角雉(Tragopan caboti)为我国特产珍禽、国家一类保护动物,分布于福建、广东、广西、浙江、江西及湖南等省的局部地区,数量已极为稀少。它的典型栖息地为亚热带常绿阔叶林及针阔混交林,海拔1,000~1,400米的山中 ...
郑光美
doaj

