Results 31 to 40 of about 7,870 (139)
Zhongguo shiyan zhenduanxue, 2020 目的研究FGG蛋白在结直肠癌及其周围的癌旁组织的表达情况,探讨FGG在结直肠癌中的临床意义,以及评价作为该病肿瘤标志物的潜力。方法应用液质联用技术,分析结直肠癌中表达的差异蛋白情况,利用Western blot方法对其准确性进行验证。结果经质谱鉴定后得出FGG在结直肠癌中较正常组织中表达增高,Western blot结果与之吻合。结论可将FGG视为结直肠癌病情监测以及疗效预测中的潜在标志物之一。
马舒婷, 谢风, 刘金华, 李威
doaj
Zhejiang Daxue xuebao. Lixue ban, 2013 采用离子色谱(IC)和光化学衍生荧光检测(PCF)联用技术，建立了保健品中核黄素的分析方法.色谱柱选用Dionex Ion Pac AG11-HC保护柱(4 mm×50 mm)和Ion Pac AS11-HC分析柱(4 mm × 250 mm)，淋洗液为40 mmol• L-1 NaOH.待测物通过自制光化学反应器(254 nm)在线衍生，核黄素转化为强荧光物质，从而以荧光检测器检测.在优化的实验条件下，对50 mg • L-1的核黄素溶液平行测定6次的保留时间和峰面积相对标准偏差分别为0.6%和2.1%
CAOSheng-lin(曹盛林) +4 more
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The Study on Pharmacodynamics and Pharmacokinetics of (Z)-(S)-9-octadecenamide, N-(2-hydroxyethyl,1-methy) [PDF]
, 2011 过氧化物酶体增殖物激活受体α（PPARα）是PPARs中的一个亚型，它在单核巨噬细胞、内皮细胞以及平滑肌细胞均有表达。PPARα可以通过直接作用于动脉管壁，抑制单核细胞向血管内皮聚集并转化为巨噬细胞，抑制血管平滑肌细胞增殖和迁移以及泡沫细胞的形成等，与防治动脉粥样硬化密切相关。一种内源性大麻素油酰乙醇胺（Oleoylethanolamide，OEA）是PPARα的天然配体，在激活PPARα时存在结构选择性。本论文研究的化合物S-油酰丙醇胺是OEA的结构类似物，具光学活性，体外分子实验结果表明S ...
郑城微
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Determination of Aflatoxins in Grains by QuEChERS-UPLC-MS/MS [PDF]
A method based on a QuEChERS sample preparation approach coupled with ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) was established to determine six aflatoxins (B1, B2, G1, G2, M1, M2) residues in grains.
CHEN Lu +4 more
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Fushe yanjiu yu fushe gongyi xuebao随着核电在中国能源结构中地位的不断提升，核电厂液态流出物中的氚减排问题已成为核电发展过程中必须解决的关键问题。分析现有的氚水处理技术，针对核电厂液态流出物中氚浓度低且流出量大的特点，以及高减容因子和高安全、经济性要求，本研究提出了一种水精馏（WD）-联合电解催化交换（CECE）级联的氚减排工艺。结合国内主力堆型的液态流出物氚减排需求，进行了初步方案设计和能耗评估。结果表明，采用该设计方案后，核电厂液态流出物中的氚去污因子可达到20.4，氚物质的量减容倍数可达4 857，显著提高了氚减排效率 ...
王 君妍, 高 娇, 陈 超
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基质辅助激光解吸电离飞行时间质谱技术分析三七和海兔神经连索内的皂甙组分 [PDF]
, 2009 基质辅助激光解吸电离飞行时间(MALDI-TOF)质谱技术能高效解吸三七提取液(Panaxnotoginseng Extraction,PNE)中的混合皂甙分子为皂甙离子,并供质量分析器检测与分析。选用MALDI-TOF质谱技术直接分析色谱纯皂甙样品的纯度,其检测灵敏度优于反相高效液相色谱法(RP-HPLC)。优化提取中药三七(Panax notoginseng,PN)的混合皂甙,选用MALDI-TOF质谱技术直接分析PNE中的皂甙种类和相对含量,发现PNE至少含有20种不同分子结构的皂甙组分 ...
冯丽剑, 卓慧钦, 黄河清, 黄琳
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Research Progress on Separation and Purification Technology of Quinoa Saponins [PDF]
Quinoa saponins are a kind of pentacyclic triterpenoids with important physiological and pharmacological activities. Due to the wide variety and wide polarity span, the conventional purification and separation methods not only require a lot of work, but ...
NIU Yan +5 more
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Effect of Aging Time on Volatile Aroma Compounds of Apple Brandy(不同陈酿时间苹果白兰地主要香气成分变化分析) [PDF]
Shipin kexue jishu xuebao, 2019 The volatile aroma compounds of apple brandy with different aging time in oak barrel were determined by liquid-liquid extraction and gas chromatography-mass spectrometry and analyzed by cluster analysis methods.
ZENG Chaozhen(曾朝珍) +5 more
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Probing the mechanism of anti-gout action of Erythropalum scandens Bl. based on UPLC-QE-Orbitrap-MS combined with network pharmacology [PDF]
Objective To investigate the potential gout treatment mechanisms and targets of Erythropalum scandens Bl. through network pharmacology and molecular docking techniques and experimental validatio based on ultra-performance liquid chromatography-quadrupole-
Bizuan HE +10 more
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载体硅烷化改性对W/MCM-22催化剂上甲烷脱氢芳构化反应性能的影响 [PDF]
, 2006 用正硅酸乙脂(TEOS)和三甲基氯硅烷(TMCS)为硅烷化试剂,分别对MCM-22分子筛进行表面改性处理,考察其对所担载W/MCM-22基催化剂上甲烷脱氢芳构化(DHAM)反应性能的影响,结果表明,TEOS或TMCS对MCM-22分子筛载体的硅烷化处理主要导致分子筛外表面最强和最弱的表面酸性位被消去,分子筛孔道内的B酸位(芳构化中心)几不受影响;在DHAM反应化学上表现为:CH4转化率大体持平,但芳烃选择性明显上升,催化剂的结焦/积碳速率有所减缓,单程操作寿命明显延长.在经硅烷化处理的8%W-0.6 ...
张鸿斌 +4 more
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