Analysis of group 12a lymph node metastasis at different sites of gastric adenocarcinoma and its risk factors [PDF]
Background and purpose: It is not clear that the pattern of lymph node (group 12a) metastasis within the hepatoduodenal ligament (along the hepatic artery) in gastric cancer, its indications for dissection are still controversial, and there is a lack of ...
DU Shuxiang, ZHAO Yingzhi, ZHANG Xuetao, WANG Tao, LUO Jingyu, ZHANG Wei, WU Gang
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Clinical study on high-risk factors for contralateral lymph node metastasis in unilateral papillary thyroid carcinoma [PDF]
Background and purpose: The occurrence of lymph node metastasis in papillary thyroid cancer (PTC) can have adverse effects on the prognosis of patients. This study aimed to investigate risk factors related to the occurrence of contralateral central lymph
YUAN Xinyue, YAO Yao, CHENG Shuai, ZHENG Xin, ZHANG Yuan
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Detection of EGFR and COX-2 Expression by Immunohistochemical Method on a Tissue Microarray Section in Lung Cancer and Biological Significance [PDF]
Background and objective Epidermal growth factor receptor (EGFR) and cyclooxygenase-2 (COX-2), which can regulate growth, invasion and metastasis of tumor through relevant signaling pathway, have been detected in a variety of solid tumors.
Congzhong ZHU, Juan LIU, Xinyun WANG
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Predictive Value of Combined Use of Ultrasonographic Indicators for Central Lymph Node Metastasis in Papillary Thyroid Carcinoma [PDF]
BackgroundThe treatment scheme for papillary thyroid carcinoma (PTC) patients is related to whether lymph node metastasis is prevalent or not. The routine ultrasound indicator used alone has proven to have a low sensitivity to predict the presence of ...
ZHANG Xiaomei, KANG Yanfei, SANG Tian, CHENG Jing, LI Qiaoli, CAO Yuwen, MA Jinmei, SHI Linan, LI Wenxiao, LI Jun
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Expression and Significance of gp96 and Immune-related Gene CTLA-4, CD8 in Lung Cancer Tissues [PDF]
Background and objective It has been proven that gp96 plays an important role in specific cytotoxic immune response which is involved in anti-tumor effect in the body.
Haiyan ZHENG +4 more
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The Role of Postoperative Radiotherapy on Stage N2 Non-small Cell Lung Cancer [PDF]
Background and objective The clinical value of postoperative radiotherapy (PORT) in stage N2 nonsmall-cell lung cancer (NSCLC) is controversy. The aim of this study is to analyze the efficacy of PORT in subgroup of stage N2 NSCLC, which can help ...
Changli WANG +7 more
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Clinicopathological Research and Expression of PTEN/PI3K/Akt Signaling Pathway in Non-small Cell Lung Cancer [PDF]
Background and objective It has been known that abnormality of PTEN/PI3K/Akt signal pathway played an important role in initiation of some malignant tumors.
Can XU +3 more
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Expression and clinical significance of RRM1,CDX2 in gastric cancer tissues [PDF]
目的探讨RRM1、CDX2在胃癌组织中的表达,并分析其与胃癌侵袭与转移的关系。方法选取90例术前未行放化疗的胃癌石蜡标本及与其对应正常胃黏膜蜡标本30例,采用SP免疫组化方法检测RRM1和CDX2在两种组织中表达情况,分析二者表达与分化程度、浸润深度、淋巴结转移、TNM分期之间的关系。结果 (1)RRM1、CDX2在胃癌中的阳性表达率均显著高于正常胃黏膜组(86.7%vs 40.0%,P〈0.01;61.1%vs 16.7%,P〈0.01)。(2)90例胃癌中,RRM1与CDX2二者之间呈正相关关系 ...
刘美莲 +6 more
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Expressions of Cyr61 and WISP-3 in Non-small Cell Lung Cancer and Its Clinical Significance [PDF]
Background and objective Cysteine-rich protein 61 (Cyr61) plays a role as a tumor suppressor in non-small cell lung cancer (NSCLC). Cyr61 and WISP-3 have a very significant sequence homology, belonging to the same CCN gene family.
Chunwei ZHANG +3 more
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Expression and Clinical Relevance of uPA and ET-1 in Non-small Cell Lung Cancer [PDF]
Background and objective uPA and ET-1 proteins have been reported to be up-regulated in some of human cancers. The aim of this study is to investigate the alteration and clinical relevance of uPA and ET-1 protein levels in non-small cell lung cancer ...
Boshi WANG +7 more
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