[C/EBPβ mediates expressions of downstream inflammatory factors of the tumor necrosis factor-α signaling pathway in renal tubular epithelial cells with NPHP1 knockdown]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoHuang D +5 more
europepmc +1 more source
[Volatile oil from <i>Acorus tatarinowii</i> Schott ameliorates tic disorder in rats by inhibiting TLR4/MyD88/NF-κB-mediated microglial polarization]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoFeng P +7 more
europepmc +1 more source
环酯红霉素调控NF-kB/PI3K-Akt信号通路抑制小儿支气管肺炎炎症反应的作用机制研究
Zhongguo shiyan zhenduanxue目的探讨环酯红霉素调控NF-κB/PI3K-Akt信号通路抑制小儿支气管肺炎炎症反应的作用机制。方法采用LPS诱导人支气管上皮细胞（16HBE）建立体外炎症模型，设置对照组、LPS组及环酯红霉素低、中、高剂量组（12.5、25.0、50.0 μg/mL）。建立LPS气管滴注诱导的幼年SD大鼠支气管肺炎模型，分为假手术组、模型组、环酯红霉素低、中、高剂量组（25、50、100 mg/kg）及地塞米松阳性对照组。检测炎症因子、氧化应激、细胞凋亡及NF-κB、PI3K-Akt通路蛋白表达 ...
杨丽曼, 高艳清, 张冲, 闫学爽
doaj
Zhongshan Daxue xuebao. Yixue kexue ban, 2009 【目的】 观察周期性与持续性营养输注方式对内科呼吸衰竭机械通气病人血糖及血清炎症因子的影响。【方法】 采用交叉的自身对照方式测定60例内科呼吸衰竭机械通气患者周期性与持续性营养输注方式过程中血糖水平的变化及营养输注前后血清炎症因子水平变化,比较两种输注方式对机械通气患者血糖及血清炎症因子的影响。【结果】 24 h持续输注组总体血糖水平低于16 h周期性输注组,分别为[(8.37 ± 2.30)mmol/L,(8.89 ± 2.77)mmol/L,P = 0.000 ...
doaj
[Oral homeostasis imbalance under hypoxia]. [PDF]
Hua Xi Kou Qiang Yi Xue Za ZhiXu Y, Wang S, Zhou J.
europepmc +1 more source
Zhongshan Daxue xuebao. Yixue kexue ban免疫介导的炎症性疾病（IMIDs）是一大类由免疫系统异常激活导致的慢性炎症性疾病，其特征是促炎细胞因子过度释放和抗炎调节信号不足的失衡。白细胞介素6（IL-6）是一种多效性细胞因子，因其独特的“三位一体”信号传导机制（经典途径、反式信号传导和反式呈递）而成为连接固有免疫与适应性免疫的“分子桥梁”。IL-6信号通路驱动急性相炎症反应，并以多种机制参与固有免疫的激活及适应性免疫调控，是驱动IMIDs炎症反应、导致多器官损害的关键途径。靶向IL-6通路的药物通过精准阻断IL-6/IL-6受体/gp130信号轴，
吴滔, 戴冽
doaj
[Identification of efferocytosis-related genes in osteoarthritis and prediction of traditional Chinese medicines based on bioinformatics and machine learning]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoXiang K +5 more
europepmc +1 more source
[Research progress on the causes of pain in knee osteoarthritis]. [PDF]
Zhongguo Xiu Fu Chong Jian Wai Ke Za ZhiWei N, Zheng Z.
europepmc +1 more source
[Eurycomanone inhibits renal ischemia/reperfusion-induced mitochondrial dysfunction and inflammation in mice by binding to STAT3 to inhibit its phosphorylation]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoLiu Z +8 more
europepmc +1 more source
[Research advances on the targeted programmed cell death regulatory network for treatment of refractory diabetic wounds]. [PDF]
Zhonghua Shao Shang Yu Chuang Mian Xiu Fu Za ZhiZhang ZH, He WF.
europepmc +1 more source