Results 51 to 60 of about 17,372 (167)
Linchuang shenzangbing zazhi, 2014 急性肾损伤(acute kidney injury,AKI)是住院患者尤其是危重症患者中的常见病。尽管对其研究和认识已不断深入,但其病死率仍居高不下。影响其预后的一个主要原因是缺乏早期诊断的生物标志物。迄今为止,在一些研究中已先后发现了多种具有潜力的AKI生物标志物,并有不少研究结果显示这些生物标志物可能在AKI的早期诊断、病情及疗效监测、预后评估中具有重要意义,有望改善AKI患者预后。
张敏
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Source apportionment of source-specific biomarkers from sedimentary organic matters and coastal organic aerosols in Taiwan Stra [PDF]
, 2017 在海-陆相互作用（如河流输入和大气沉降等）和人类活动（如化石燃料燃烧等）的影响下，大量的陆源有机质由河流和风尘携带下被输送到边缘海，导致边缘海沉积碳汇同时也是一个重要的陆源有机碳汇。由于不同的来源的有机碳汇在不同时间尺度上影响着大气CO2的浓度，正确认识海洋的沉积碳汇对于全面了解全球碳循环具有重要意义。河流和大气的颗粒物输送是海洋沉积陆源物质的两个重要来源，由于传输途径的差异导致了河流和大气输送的有机质在物理生物化学性质和在传输埋藏的行为上有很大的差别。从海-气相互作用的角度来看 ...
陶舒琴
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Ultrasound in Obstetrics &Gynecology, Volume 65, Issue 6, Page 749-760, June 2025.ABSTRACT Objective Placental dysfunction can result in small‐for‐gestational age (SGA) or fetal growth restriction (FGR). The aim of this prospective cohort study was to assess the association of the cerebroplacental ratio (CPR) and other more conventional fetoplacental Doppler indices, circulating placental growth factor (PlGF) levels and soluble fms ...
J. Hong +6 more
wiley +1 more source
The development for emerging biomarkers of lymphangioleiomyomatosis
Orphanet Journal of Rare Diseases抽象 Lymphangioleiomyomatosis (LAM) is a rare, slowly progressing, low-grade metastatic tumor primarily affecting women. Currently, vascular endothelial growth factor–D (VEGF-D) is the only validated diagnostic biomarker, enabling diagnosis of LAM without ...
Liting Huang +3 more
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Ultrasound in Obstetrics &Gynecology, Volume 65, Issue 4, Page 470-477, April 2025.ABSTRACT Objective To evaluate the presence and levels of cytomegalovirus (CMV) cell‐free DNA (cfDNA) fragments in women pregnant with a fetus with symptomatic congenital CMV (cCMV). Methods The study comprised nine women whose fetuses were diagnosed with cCMV between June 2019 and July 2024 at 20 + 4 to 34 + 1 weeks' gestation (n = 8) or neonatally (n
B. H. W. Faas +9 more
wiley +1 more source
Shuitu Baochi Xuebao, 2005 水是环境中污染物迁移的重要介质,水系污染物也可以直接作用于生物体。本文概述了对水系物质迁移过程示踪的各种方法,包括人工示踪剂方法、生物标志法、微量元素及同位素示踪方法等,指出了它们的环境应用价值。在人工示踪法中叙述了中子活化示踪沙技术和稀土元素-DTPA螯合物示踪法。生物标志物主要叙述了木质素、正构烷烃、脂肪酸的指示意义。微量元素示踪主要涉及到Sr、Ca、Mg和REE的示踪。同位素示踪法着重阐述了较先进的碳、氮、氧和铅同位素的示踪。最后展示了水系物质示踪的应用前景。
李阿梅 袁旭音 乔磊
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Ultrasound in Obstetrics &Gynecology, Volume 65, Issue 4, Page 447-455, April 2025.ABSTRACT Objective A soluble fms‐like tyrosine kinase‐1 (sFlt‐1)‐to‐placental growth factor (PlGF) ratio cut‐off of 38 is currently considered optimal for ruling out pre‐eclampsia (PE); however, implementation of this ratio in clinical practice is limited.
M. N. Nan +15 more
wiley +1 more source
Study on the mechanisms of Pygopus-2 promoting invasion and metastasis in hepatocellular carcinoma [PDF]
, 2016 第一部分Pygopus-2在HCC中高表达与病人恶性预后密切相关 Pygopus-2是经典Wnt/β-Catenin信号通路转录复合体的重要成分。本研究目的是观察在原发性肝癌中Pygopus-2的表达情况及相关的临床病理意义。RT-PCR的方法检测50对肝癌病人组织标本中癌组织与癌旁组织中Pygopus-2的mRNA表达情况，结果发现癌组织中Pygopus-2的mRNA水平明显高于癌旁组织(P=0.009)。免疫组化分析显示异常表达的Pygopus-2蛋白与肝癌病人的年龄(P=0.025)、肿瘤大小(P=
李杰
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The homogenization of China's city flowers and city trees
People and Nature, Volume 7, Issue 2, Page 530-540, February 2025.Abstract Cultural homogeneity, similar to the loss biodiversity, is a significant global issue that is increasingly gaining attention. City flowers and city trees (CFTs) serve as emblematic cultural symbols of modern cities, often referred to as the ‘green business card’. While many cities have established CFTs in recent decades, there are instances of
Zhuo Cheng +6 more
wiley +1 more source
液相色谱-质谱联用技术筛查synemin蛋白及其在肾癌诊断中的作用
Zhongguo shiyan zhenduanxue, 2020 目的本研究的目的是利用化学和生物信息学的方法寻找肾癌和癌旁组织的差异蛋白,探讨目标蛋白作为肾癌生物标志物的可能性。方法采用液相色谱-质谱法鉴定肾癌和癌旁组织差异表达的蛋白,借助免疫组织化学的方法观察肾癌和癌旁组织标本中synemin蛋白的表达。结果肾癌与癌旁组织差异表达的蛋白有26个,肾癌组织中过表达18个,低表达8个。synemin蛋白在肾癌组织中的高表达,统计学差异明显 ...
谭文佳 +3 more
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