Results 31 to 40 of about 17,372 (167)
Rare Metals, Volume 45, Issue 2, February 2026.ABSTRACT Intervertebral disc degeneration (IDD) is a predominant cause of low back pain, significantly impacting quality of life. Mitochondrial fitness is essential in the progression of IDD, as it regulates cellular senescence and pyroptosis. This study investigates the role of mitochondrial caseinolytic protease P (ClpP) in alleviating senescence and
Kun Wang +7 more
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Zhongguo shiyan zhenduanxue, 1997 肿瘤标志物与肿瘤免疫治疗袁玫作者单位：１００８５３北京，解放军总医院肿瘤生物学研究室肿瘤标志物肿瘤标志物是指应用免疫学和分子生物学等方法发现的生物、生化分子，它们表达于肿瘤细胞，而不表达于正常细胞或表达量大大小于肿瘤细胞。换言之，肿瘤生物标志物可以是...
袁玫
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数字生物标志物：打开数智医疗应用的钥匙 Digital Biomarkers: Unlocking the Potential of Digital Intelligent Healthcare
Zhongguo cuzhong zazhi数字生物标志物是借助数智技术，通过可穿戴设备等工具主动或被动采集个体的行为、生理或生化数据，再经人工智能算法分析构建的新型指标。近年来，数字生物标志物研究在糖尿病、心血管疾病、癫痫、帕金森病及抑郁症等领域发展迅猛，但其在脑血管病领域的应用尚处于初期阶段。本文对比传统与数字生物标志物的区别，介绍常用的数字设备类型，探讨数字生物标志物的筛选、应用及挑战，并结合脑血管病特点分析其潜力，以期为推进脑血管病个体化医疗、药物与脑机接口技术研发提供新思路。 Abstract: Digital ...
周宏宇1，2，李子孝1，2 （ZHOU Hongyu1,2, LI Zixiao1,2 ）
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Smart Biomaterials and Dressings for the Treatment of Chronic Inflammatory Skin Diseases
Rare Metals, Volume 45, Issue 2, February 2026.ABSTRACT Chronic inflammatory skin diseases, encompassing immune‐inflammatory conditions and infection‐associated dermatoses, pose significant clinical challenges due to high prevalence, recurrence, and therapeutic resistance, affect over 30% of the global population.
Zehao Lan +5 more
wiley +1 more source
Clinical value of alpha-fetoprotein: alpha-fetoprotein-L3 isoform ratio and des-γ-carboxyprothrombin in early diagnosis of HBV-related hepatocellular carcinoma [PDF]
, 2023 Objective To evaluate the value of different combinations of alpha-fetoprotein （AFP）， alpha-fetoprotein-L3 isoform ratio （AFP-L3%） and des-γ-carboxyprothrombin （DCP） for early diagnosis of hepatitis B virus （HBV）-related hepatocellular carcinoma （HCC ...
Duan Jianping, Du Lei, Song Ting, Liu Zhensheng
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International Journal of Applied Linguistics, Volume 36, Issue 1, Page 714-724, February 2026.ABSTRACT Interlingual translation, as defined by Roman Jakobson, refers to the transfer of meaning between languages. However, this concept has often been conflated with linguistic shifts between distinct cultures and nation‐states. To challenge this misconception, I propose the concept of self‐consumption translation (SCT), a subfield of interlingual ...
Bilin (Belen) Liu
wiley +1 more source
流式荧光发光法及其改进技术的临床多肿瘤标志物样本结果对比分析及评价
Zhongguo shiyan zhenduanxue, 2018 肿瘤标志物(Tumor Marker,TM)是一种由肿瘤细胞产生和释放,以抗原、酶或激素等代谢产物的形式存在于肿瘤细胞内或体液中的物质[1]。由于肿瘤细胞的生化性质及代谢情况与健康细胞相比表现异常,因此在人的体液、排除物及组织中,肿瘤标志物会出现质或量上改变的,故根据其生化或免疫特性可以识别或诊断肿瘤的状况 ...
赵虹, 姚华, 张海山
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Effects of marine pollution on the expression of hepatic HSP60 and HSP70 protein in Sebastiscus marmoratus [PDF]
, 2015 摘要 热应激蛋白(HeatShockProteins，HSPs)是一种生物体内普遍适用并高度存在的应激蛋白，在外界污染影响下，HSPs的表达量发生变化，能快速保护细胞对抗外源性或内源性应激的攻击，提高细胞的修复能力并增强细胞对付应激的耐受程度。HSPs的诱导被认为是反映环境污染状况最灵敏的生物学反应之一，本文着重研究海洋鱼类HSP60和HSP70蛋白对常见海洋污染物的响应规律，探讨作为生物标志物的可行性。 本研究利用蛋白印迹法测定不同浓度石油水溶性成分(watersolublefraction,WSF)(
王毅捷
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Lithology modulates soil priming effect via resource limitations and bacterial community structure
Functional Ecology, Volume 40, Issue 1, Page 176-190, January 2026.Read the free Plain Language Summary for this article on the Journal blog. Abstract The soil priming effect (PE), triggered by root exudate inputs that stimulates microbial activity and drives significant soil carbon (C) losses in terrestrial ecosystems.
Xinyu Hou +4 more
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2023 目的 本研究利用机器学习探索IgA肾病(IgAN)铁死亡的潜在诊断标志物及其生物学过程，并研究其与IgAN免疫细胞浸润的关系。方法 从GEO数据库中下载来自IgAN患者和对照组的肾小球组织的微阵列数据集(GSE93798,GSE104948),通过FerrDb数据库获取全部铁死亡相关基因数据，获得IgAN组和对照组中有差异表达的铁死亡相关基因 ...
杨柏新 +4 more
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