Evaluation of medication treatment for Alzheimer's disease on clinical evidence [PDF]
, 2014 Objective To formulate the best treatment plan for Alzheimer's disease patients by evaluating the therapeutic efficacy and side effect of various evidence-based programs.
Ling LIU +3 more
core +2 more sources
Correlations between IGF-IR Expression and Clinicopathological Factors and Prognosis in Patients with Lung Adenocarcinoma [PDF]
, 2010 Background and objective The incidence of lung adenocarcinoma increases rapidly, and IGF-IR is the key mediator of several growth factors signal transduction, therefore it plays an important role in the proliferation and differentiation of cancer cell ...
Baohui HAN +4 more
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Advances in Elemene Nanodelivery Systems: From Material Design to Disease Treatment
Rare Metals, EarlyView.ABSTRACT Elemene (ELE) is a bioactive sesquiterpenoid extracted from traditional Chinese herbs, demonstrating broad‐spectrum antitumor, anti‐inflammatory, and analgesic properties with significant therapeutic potential. However, its clinical utility is constrained by inherent physicochemical limitations, including volatility and hydrophobicity, which ...
Xiao Wang +9 more
wiley +1 more source
Association between Polymorphisms of ERCC1 and Response in Patients with Advanced Non-small Cell Lung Cancer Receiving Cisplatin-based Chemotherapy [PDF]
, 2010 Background and objective Results of studies on genetic polymorphisms of ERCC1 gene in DNA repair pathway which may affect response to platinum-based chemotherapy and survival in patients with non-small cell lung cancer are conflicting.
Hui ZHANG +6 more
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New Advances of Degradable Magnesium‐Based Metal Biomaterials in the Field of Orthopedics
Rare Metals, EarlyView.ABSTRACT Based on their outstanding biomechanical properties and superior osteogenic activity, magnesium (Mg) and its alloys have been extensively investigated for their biocompatibility and therapeutic efficacy in treating fractures and bone defects.
Jia‐Nan Yu +8 more
wiley +1 more source
Clinical Study on the Treatment of Depression Qi stagnation and Phlegm stagnation Syndrome with Chai Yu Wen Dan Decoction [PDF]
, 2016 背景: 抑郁症是由各种原因引起的，以显著而持久的情绪低落、兴趣和活动性减低为主要临床表现的精神障碍性心理疾病。现代社会由于生活工作压力增大、节奏变快、竞争激烈等，抑郁症的发病率呈上升趋势。抗抑郁西药应用于临床已半个多世纪，证实多数药物有确切的疗效，但仍然存在着抗抑郁谱窄、起效缓慢、存在不同程度不良反应、患者依从性较差等问题。近年来中药复方以其多途径、多靶点及多环节的综合药理效应治疗抑郁症已凸显一定优势。 目的: 1.通过文献研究探索中医药治疗抑郁症的优势所在 ...
郭冠呈
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Rare Metals, EarlyView.ABSTRACT Multi‐element Prussian blue analog (PBA) nanocomposites have attracted wide attention for their superior characteristics to single‐functional nanomaterials in extensive applications of diagnosis and therapy. In this study, a novel hollow nanocomposite was designed and fabricated by embedding S2− and Ag nanoparticles into a NiCuMnFe (PBA).
Tao Ji +7 more
wiley +1 more source
The Impact of Smoking Status on the Efficacy of Erlotinib in Patients with Advanced Non-small Cell Lung Cancer [PDF]
, 2009 Background and objective Erlotinib is a targeted treatment for advanced non-small cell lung cancer. Smoking status may be one of influencing factors of the efficacy of erlotinib.
Jinji YANG +5 more
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Rare Metals, EarlyView.ABSTRACT Periodontitis is a chronic infectious oral disease triggered by periodontopathogenic bacteria, resulting in the progressive inflammation and destruction of the tissues surrounding teeth. To achieve reprogramming of the infectious microenvironment for periodontitis therapy, a nanoformulation was proposed by loading polydopamine (PDA) with ...
Hao Liang +14 more
wiley +1 more source
BSD2000 Deep Hyperthermia Combined with Chemotherapy of PT regimen in Patients with Non-small Cell Lung Cancer [PDF]
, 2010 Background and objective The aim of this study is to determine the short-term efficacy, toxicity and the rate of life-quality improvement of BSD2000 deep hyperthermia combined with chemotherapy of PT regimen in patients with non-small cell lung cancer ...
Jun ZHAO, Mengxiang YANG, Yanwen WANG
core