Results 21 to 30 of about 29,479 (145)
Anticancer Application and in Vivo Behavior Study of Two-Dimensional Pd Based Near-infrared Photothermal Nanomaterials [PDF]
, 2016 近年来随着纳米技术的快速发展，纳米医学作为纳米科学的重要分支，即用纳米技术来解决医学问题的学科，为恶性肿瘤的诊断和治疗提供了新的思路和手段。本论文主要研究二维贵金属钯基纳米材料在光热治疗、光动力学治疗以及光热-光动力、光热-化疗联合治疗方面的应用，并且进一步探讨纳米材料的表面修饰及二维纳米材料特殊的形貌对其活体行为的影响。主要的研究结果概括如下： 第一章：简单介绍了光热治疗、光动力治疗技术，以及无机光热纳米材料在光热治疗方面的应用进展。此外也简单总结了纳米颗粒的形貌、尺寸 ...
师赛鸽
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Veterinary Dermatology, EarlyView.Background: Canine atopic dermatitis (cAD) is a common, chronic skin condition characterised by epidermal barrier dysfunction, immune dysregulation and cutaneous dysbiosis. While “emollient plus” formulations are widely used in human atopic dermatitis, their role in cAD remains underexplored. Hypothesis/Objectives: To evaluate the clinical efficacy and
Beatriz Fernandes +8 more
wiley +1 more source
The Analysis of Erlotinib on Brain Metastases in Patients with Non-small-cell Lung Cancer [PDF]
, 2009 Background and objective Brain metastases are common in non-small-cell lung cancer (NSCLC) and the prognosis is poor. Erlotinib is a specific inhibitor of the epidermal growth factor receptor-associated tyrosine kinase (EGFRTKI), which has been gradually
Baohui HAN, Hao BAI
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Veterinary Dermatology, EarlyView.Background: DNA‐based vaccination rapidly induces strong cellular and humoral immune responses, which may be enhanced by inclusion of lysosomal‐associated membrane protein‐1 (LAMP). Objectives: This proof‐of‐concept study evaluated the efficacy and safety of a Der f 2/Zen 1‐LAMP‐based DNA vaccine immunotherapy in client‐owned dogs with nonseasonal AD ...
Petra Bizikova +6 more
wiley +1 more source
The role of arsenic nano-drug in the treatment of liver cancer [PDF]
, 2015 目的：三氧化二砷（ATO）是临床上能够有效治疗急性早幼粒细胞性白血病的药物。然而，由于治疗剂量限制和药代动力学欠佳，影响了它在抗肿瘤治疗中的运用。亲合体（Affibody）是一类新型独特的蛋白结合配体，分子量小、亲和力强、稳定且可修饰，比普通抗体具有更多优势。目前国内外尚无将亲合体用于肝癌靶向治疗的研究。为了更加有效地将ATO药物运输到肝癌细胞并产生更高的毒性，我们前期已经合成了两种新型砷纳米药物：EGFR靶向修饰的镍砷纳米药物（Ni,As@SiO2-Affibody）、锰砷纳米药物（Mn,As ...
李辉
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A Tale of Two Programs? Stigma and Administrative Burdens in CHIP and Medicaid
World Medical &Health Policy, Volume 18, Issue 1, March 2026.ABSTRACT One contributing factor to undersubscriptions is administrative burdens. To explore whether program stigma affects attitudes about administrative burdens, a survey (N = 2204) was fielded to assess differences in attitudes about seven policies decreasing administrative burdens and two policies increasing administrative burdens.
Simon F. Haeder
wiley +1 more source
A meta-analysis of Pemetrexed plus Platinum Chemotherapy versus Gemcitabine plus Platinum Chemotherapy for Advanced Non-small Cell Lung Cancer [PDF]
, 2011 Background and objective Whether pemetrexed plus platinum (PP) regimen is superior to gemcitabine plus platinum (GP) regimen for patients with advanced non-small cell lung cancer (NSCLC) is unclear.
Jin JIANG +5 more
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Politics &Policy, Volume 54, Issue 1, February 2026.ABSTRACT Psychedelic interventions are not publicly available through Canada's healthcare system. Despite growing scientific evidence, public interest, and efforts to expand access to psychedelic therapies for end‐of‐life psychological suffering, Canadian policies remain restrictive.
Sarah Kratina +4 more
wiley +1 more source
Clinical Observation of Erlotinib in the Treatment of Advanced Non-small Cell Lung Cancer: A Report of 92 Eases [PDF]
, 2009 Background and objective Erlotinib, a selective inhibitor of epidermal growth factor receptor tyrosine kinase, has been approved effective in local advanced or metastatic non-small cell lung cancer (NSCLC).
Aiqin GU +5 more
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Veterinary Dermatology, Volume 37, Issue 1, Page 89-102, February 2026.ABSTRACT Background Recurrent otitis externa (OE) episodes commonly affect dogs with canine atopic dermatitis (cAD) despite ongoing cAD treatment. Objective To determine if a therapeutic diet with active ingredients targeting the skin barrier and allergy pathways reduces the incidence rate of OE.
Adrian Watson +5 more
wiley +1 more source