Results 11 to 20 of about 864,121 (164)

糖尿病患者ICU病原菌分布临床分析

Zhongguo shiyan zhenduanxue
目的探讨ICU中糖尿病患者病原学分布的临床特征。方法回顾性分析吉林大学白求恩第三医院ICU收治的223例病原菌阳性感染患者临床及细菌学培养资料。比较糖尿病与非糖尿病重症患者病原菌分布的差异。结果其中非糖尿病组51例（22.87%），糖尿病组172例（77.13%），与非糖尿病组相比糖尿病组白细胞总数及中性粒细胞总数明显升高（P<0.05）。两组均以革兰阴性菌感染为主，非糖尿病组革兰阴性菌占70.89%(56/79),革兰阳性菌占22.78%(18/79),真菌占6.33%(5/79 ...
马佳琳, 王智宣, 冯野
doaj   +2 more sources

孢子丝菌病及其病原真菌的再认识 [PDF]

, 2021
孢子丝菌病是由双相型真菌孢子丝菌复合体引起的皮肤黏膜、皮下组织及局部淋巴系统的慢性感染性疾病，可播散至全身引起多系统损害，是一种全球性的人畜共患真菌病，临床表现以固定型和淋巴管型为主。病原真菌孢子丝菌复合体包含多种孢子丝菌，它们在微观形态学、遗传学、流行病学、耐药性和致病性等方面存在差异。孢子丝菌复合体的致病性与其本身的黑素、粘附因子及几丁质等毒力因素有关。课题组参与了孢子丝菌复合体的全基因组和转录组的测序分析工作和对孢子丝菌毒力因素研究 ...
黄怀球
core   +1 more source

Host–Guest Interactions Govern Drug Stability and Controlled Therapeutic Release: Based on Metal–Organic Frameworks as Smart Platforms

Rare Metals, Volume 45, Issue 8, August 2026.
ABSTRACT Due to their exceptional porosity, structural versatility, and modular coordination chemistry, metal–organic frameworks (MOFs) have emerged as versatile platforms for targeted drug delivery. These structures enable fine‐tuning of pore size, surface activity, and framework stability for the encapsulation of a broad range of therapeutics ...
Rui Hua, Kai You, Qifang Liu, Mengjie Chen, Li Sun, Aochi Liu, Jie Lin, Yang Song, Shasha Yu, Haishan Zhang   +9 more
wiley   +1 more source

Acoustically Assisted Heterojunction Hydrogel Promotes Angiogenesis and Tissue Regeneration by Modulating the Inflammatory Microenvironment

Rare Metals, Volume 45, Issue 8, August 2026.
ABSTRACT The healing of diabetic chronic wounds is hindered by multiple pathological barriers, including oxidative stress imbalance induced by hyperglycemia, persistent bacterial infection, and impaired neovascular function. This study developed an F127–HA–BiOCl@CeO2 (FHBC) hydrogel dressing with acoustic responsiveness, achieving tissue repair through
Ran Zhao, Yixuan Song, Wencan Zhang, Chen Liu, Xichao Wang, Xinyang Guo, Jiaming Zhang, Zihao Liu, Le Li   +8 more
wiley   +1 more source

High‐Throughput Development of Advanced Metallic Glasses via Compositionally Graded Thin‐Film Combinatorial Strategy

Rare Metals, Volume 45, Issue 8, August 2026.
ABSTRACT Advanced metallic glasses, leveraging their ultrahigh strength, excellent corrosion resistance, superior soft magnetic properties and good biocompatibility, have gradually become indispensable strategic cornerstones in critical fields such as aerospace, electronic information and energy power. This unique combination of properties enables them
Yizhou Liu, Yebei Wang, Jinning Xie, Meichen Jian, Yunhe Gao, Yue Huang, Yan Li, Wenlin Liu, Fu Xu, Juntao Huo, Junqiang Wang, Meng Gao   +11 more
wiley   +1 more source

An Organo‐Pt(II) Photosensitizer With Robust Photo‐Assisted Antibacterial and Wound Recovery Performances in Diabetic Mice Wound Model

Rare Metals, Volume 45, Issue 7, July 2026.
ABSTRACT The pathogenesis of diabetic foot ulcers is complex, often involving polymicrobial infection and persistent inflammatory responses, which lead to delayed or nonhealing wounds, posing a formidable clinical challenge. Existing photodynamic therapy reagents and traditional treatments generally address only a single pathological aspect, and the ...
Yu Zhang, Mengyao Han, Qianqian Cheng, Yin Jie, Qianqian Zheng, Ziwei Xu, Beixi Shi, Yueqi Zhao, Xiaofei Yang, Guangjie Zhong, Chenchen Chang, Xiaoxiao Yin, Xinai Zhong, Zhengru Fu, Shuying Bai, Hui Chong, Chengyin Wang   +16 more
wiley   +1 more source

我国淡水鱼类柱形病病原菌柱状黄杆菌的遗传多样性 [PDF]

, 2010
为认识我国淡水鱼类烂鳃病的病原以及柱形病在我国的发生情况,实验从发生烂鳃病的病鱼中分离细菌性病原,经过生理生化特性分析以及是否在含托普霉素的Shieh培养基中生长并形成黄色假根状菌落,是否产生降解明胶和硫酸软骨素的酶类等特性的鉴定,并结合16SrDNA序列分析,证实柱状黄杆菌(Flavobacterium columnare)是所分离的烂鳃病的病原。同时,研究也证实20世纪曾经命名为烂鳃(Gill-rot)病病原的鱼害黏球菌(Myxococcus piscicola Lu,Nie & Ko,1975 ...
谢海侠, 聂品, 姚卫建, 熊传喜, 张立强, 王良发, 张金, 李楠   +7 more
core  

Titanium Implant Abutments With Polydopamine‐Mesoporous Cerium Dioxide Coatings for Enhanced Antibacterial, Anti‐Inflammatory, and Soft Tissue Integration Properties

Rare Metals, Volume 45, Issue 6, June 2026.
ABSTRACT The poor soft tissue integration around titanium implants creates a microgap that serves as a pathway for pathogen invasion, resulting in infection, inflammation, and the progression of peri‐implantitis. As the implant’s transmucosal component, the abutment determines the degree of peri‐implant soft tissue attachment.
Xuan Li, Min Xing, Haoyue Liu, Kuicai Ye, Xuanyong Liu, Li Ma, Wenhao Qian, Jiajun Qiu   +7 more
wiley   +1 more source

An Ultrasound‐Triggered Antibacterial Hydrogel With Integrated Antioxidant and Angiogenic Functions for Infected Wound Care

Rare Metals, Volume 45, Issue 5, May 2026.
ABSTRACT Managing diabetic wounds requires simultaneously addressing their infectious, oxidative, and regenerative impairments. To address this, this study integrates a piezoelectric BiOCl@CuSe heterojunction (PFM‐verified) into an injectable F127/HA hydrogel, creating an ultrasound‐responsive smart dressing.
Jiayan Guo, Ximeng Zhang, Bingran Qi, Xingru Zhao, Shi‐Hang Zheng, Kezhu Li   +5 more
wiley   +1 more source

Biomimetic Metallopeptidases for Biomedical Applications: From Modular Design to Disease Treatment

Rare Metals, Volume 45, Issue 5, May 2026.
ABSTRACT Biomimetic metallopeptidases, as an emerging class of artificial enzyme systems, have demonstrated tremendous application potential in the biomedical field in recent years. Their core design principle is to rationally control amino acid composition and three‐dimensional conformation so that programmable peptide sequences can efficiently ...
Ke Ma, Ke‐Zheng Chen, Sheng‐Lin Qiao
wiley   +1 more source