Results 11 to 20 of about 18,808 (191)
[Clinicopathological Characteristics of Cervical Neuroendocrine Carcinoma and Their Relationship With Prognosis]. [PDF]
目的 探讨宫颈神经内分泌癌(neuroendocrine carcinoma, NEC)临床病理特征和预后因素,明确组织学亚型,即混合性神经内分泌癌(mixed neuroendocrine carcinoma, MiNEC)与单纯神经内分泌癌(pure-NEC)的独立预后价值。 方法 收集2015–2024年本院45例根治性手术+同步放化疗的宫颈NEC,利用免疫组化、HPV RNAScope原位杂交检测及生存分析评估临床病理特征及预后。采用1∶1倾向评分匹配校准FIGO分期后,获得17对均衡队列 ...
Lan T +7 more
europepmc +2 more sources
[Atypical clinicopathological features of monomorphic epitheliotropic intestinal T-cell lymphoma]. [PDF]
目的 探讨单形性嗜上皮性肠T细胞淋巴瘤(MEITL)的临床病理特征并讨论其诊断与鉴别诊断。 方法 纳入2015年6月至2024年1月期间苏州大学附属第四医院和浙江大学医学院附属第一医院的MEITL病例共36例,进行免疫组化、EB病毒编码的小RNA(EBER)原位杂交和T细胞受体重排检测,收集临床、实验室检查及随访资料并进行相关性研究。 结果 36例患者中男20例、女16例,中位年龄57(17~76)岁。22例(61%)出现肠道以外的病灶。32例(89%)接受手术和(或)化疗,1例接受auto-HSCT ...
Xiong DT +9 more
europepmc +2 more sources
[Clinicopathological Characteristics and Prognosis Analysis of 39 Patients with Pulmonary Sarcomatoid Carcinoma]. [PDF]
背景与目的 肺肉瘤样癌(pulmonary sarcomatoid carcinoma, PSC)是非小细胞肺癌(non-small cell lung cancer, NSCLC)的罕见类型,具有低发病率、高度恶性、强侵袭性、预后差的特点,当前无标准治疗方案。本研究拟通过收集PSC患者临床病理特征、当前诊治情况并分析预后因素,总结诊治经验,旨在提高临床对PSC的认识。 方法 回顾性收集2013年12月至2023年12月于北京胸科医院确诊、接受治疗且临床资料完整的39例PSC患者的人口学信息 ...
Chen C +6 more
europepmc +2 more sources
[Association Between the Protein Expressions of MutS Homologs and Villin and the Clinicopathological Characteristics in 310 Colon Cancer Patients]. [PDF]
目的 探究结肠癌患者错配修复蛋白MutS同系物(MutS homolog, MSH)2、MSH6、绒毛蛋白(villin)表达及与病理特征的关系。 方法 选取我院2017年1月–2021年9月经病理确诊的310例结肠癌患者,采用免疫组化法检测MSH2、MSH6和villin表达,分析MSH2、MSH6、villin表达与结肠癌患者临床病理特征的相关性。应用多因素logistic回归分析MSH2、MSH6、villin表达与结肠癌临床病理参数的相关性,用Kaplan ...
Chang F +7 more
europepmc +2 more sources
Background: Canine atopic dermatitis (cAD) is a common, chronic skin condition characterised by epidermal barrier dysfunction, immune dysregulation and cutaneous dysbiosis. While “emollient plus” formulations are widely used in human atopic dermatitis, their role in cAD remains underexplored. Hypothesis/Objectives: To evaluate the clinical efficacy and
Beatriz Fernandes +8 more
wiley +1 more source
ABCA12 Frameshift Deletion in Domestic Cats With Ichthyosis Fetalis
ABSTRACT Background Ichthyosis fetalis (IF), also known as harlequin ichthyosis, is a rare and often fatal autosomal recessive congenital skin disorder. It is characterized by thickened, hard skin plaques and deep skin fissures that limit mobility and cause malformations of the eyes, lips and ears.
Jeanna M. Blake +2 more
wiley +1 more source
The role of child language ability and parental mentalization in early child dysregulation
Abstract Dysregulation in early childhood is associated with increased vulnerability to psychopathology and poor psychosocial outcomes. While there is evidence that both child language ability and parental mentalization are associated with dysregulation in early childhood, there is little understanding of the relationships between these variables, and ...
Sara Cibralic +6 more
wiley +1 more source
ABSTRACT Objective To evaluate the proportion of optimal assessments of endometrial thickness (ET) achieved by transvaginal ultrasound (TVS) compared with a multimodal (MM) sonographic approach in women with abnormal uterine bleeding (AUB). Methods This prospective observational study was a subset of the EPI‐SURE study conducted between June and ...
S. Nijjar +5 more
wiley +1 more source
Spectacled flying‐fox Pteropus conspicillatus populations have declined so seriously over two decades that they are now endangered. Inaction has allowed threats to increase. Extreme heat events are now a lethal reality, habitat loss continues almost unabated, and pressure to disperse roosts is ever‐present. Obtaining resources and taking action to help
Noel Preece
wiley +1 more source
ABSTRACT This paper aimed to describe and analyze the factors that shaped the political priority of global neurosurgery from 2015 to 2022. The neurosurgery community formed a movement (that can be described as a global health network) to advocate for the neurosurgical patient to ensure safe, timely, and affordable neurosurgical care for all, and ...
Martina Gonzalez Gomez +3 more
wiley +1 more source

